Pediatric Pulmonary Vascular Disease

Melatonin effects on the left ventricular function in neonates with persistent pulmonary hypertension

Sarah M. Nofal, Abdel‑Rahman M. El‑Mashad, Asmaa M. Elmesiry, Amany M. Abouelenain, Mostafa M. AwnyTanta University.Egypt European Journal of PediatricsEur J Pediatr 2026; 185: DOI: 10.1007/s00431-026-06864-z AbstractThe aim of this study is to investigate the effects of melatonin on the left ventricular (LV) function in persistent pulmonary hypertension of the newborn (PPHN) and to assess its […]

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Eccentricity Index Is Associated With Pulmonary Arterial Hypertension in Children After Repair of Complete Atrioventricular Septal Defects

Charles T. Simpkin, Marissa DeLima, Morgan MacBeth, Dale A. Burkett, D. Dunbar Ivy, Benjamin S. FrankUniversity of Colorado Medical Campus and Children’s Hospital Colorado.United States Echocardiography Echocardiography 2026; DOI: 10.1111/echo.70451 AbstractIntroduction: Eccentricity Index is an echocardiographic predictor of disease severity in children with pulmonary arterial hypertension (PAH). Its utility after atrioventricular septal defect (AVSD) repair remains unclear

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Lifesaving Compassionate-Use of Sotatercept in a 12-Year-old With Idiopathic Pulmonary Arterial Hypertension

Weronika Pelczar‐Płachta, Rafał Surmacz, Waldemar BobkowskiPoznan University of Medical Sciences.Poland Pulmonary CirculationPulm Circ 2026; 16DOI: 10.1002/pul2.70293 AbstractPediatric idiopathic pulmonary arterial hypertension (IPAH) refractory to maximal medical therapy is associated with high morbidity and mortality, and therapeutic options remain limited. We describe a 12-year-old girl with end-stage IPAH who developed acute decompensated right heart failure despite triple

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Persistent pulmonary hypertension, neonatal stroke, coagulopathy and multi-organ failure due to severe enterovirus sepsis: two case reports

Arangan Kirubakaran, Kirsty Gray, Thomas Slater, Zoe Cass-Tansey, Amna Alvi, Sundar, Sathiyamurthy, Ujwal Kariholumperial College Healthcare NHS Trust. Hillingdon Hospitals NHS Foundation Trust.United Kingdom BioMedical Central PediatricsBMC Pediatr 2026; DOI: 10.1186/s12887-026-06812-8 AbstractBackground: Disseminated neonatal enteroviral infection is a rare and life-threatening condition with significant multi-organ involvement. It often presents with nonspecific symptoms that may be mistakenly

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Sildenafil for bronchopulmonary dysplasia-associated pulmonary hypertension: A systematic search and narrative synthesis

Yoshinori Katayama, Katsuya Hirata, Yutaka Nishimura, Atsuko, Nakahari, Mami Takeoka, Masahiko Watanabe, Tetsuya Isayama, Japan Evidence Based NeonatologyTakatsuki General Hospital. Osaka Women’s and Children’s Hospital. Hiroshima City Hiroshima Citizens Hospital. Jichi Medical University Saitama Medical Center. Mie University Graduate School of Medicine. National Center for Child Health and Development.Japan Pediatrics InternationalPediatr Int 2026; 68: DOI: 10.1111/ped.70385

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Multimodality imaging in a child with complete atrioventricular canal defect, left superior vena cava, and airway compression: Echocardiography, bronchoscopy, and lung ultrasound insights

Rajesh Madavathazathil Gopalakrishnan, Shashikapoor Yadav, Ashish KatewaAmrita Institute of Medical Sciences and Research Centre.India Annals of Pediatric CardiologyAnn Pediatr Cardiol 2025; 18: 628-631 DOI: 10.4103/apc.apc_261_25 AbstractCongenital heart disease may coexist with airway abnormalities, increasing perioperative risk. We report a 2-year-old girl with a complete atrioventricular canal defect (CAVCD), left superior vena cava (LSVC), and severe pulmonary

Multimodality imaging in a child with complete atrioventricular canal defect, left superior vena cava, and airway compression: Echocardiography, bronchoscopy, and lung ultrasound insights Read More »

Pulmonary Hypertension in Down Syndrome Versus Non-syndromic Pediatric Populations With Congenital Heart Disease: A Comparative Study

Tariqul Islam, Tahmina Karim, Sadia Afrin Mony, Mostafizur Rahman Bhuyan, Faizah IslamBangladesh Medical University.Bangladesh CureusCureus 2026; 18: DOI: 10.7759/cureus.104634 AbstractBackground: Down syndrome (DS), or trisomy 21, is the most common chromosomal disorder associated with congenital heart disease (CHD), profoundly affecting disease progression and management. While 4-10% of all CHD cases occur in DS, 40-60% of individuals with

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Echocardiographic diagnosis of pulmonary thromboembolism in a preterm infant presenting with congenital chylothorax

Takao Kobayashi, Sota Iwatani, Seiji YoshimotoKobe Children’s Hospital. Hokkaido University.Japan Pediatrics and NeonatologyPediatr Neonatol 2026; DOI: 10.1016/j.pedneo.2026.01.005 AbstractAbstract Not Available CategoryPrimary Pulmonary Lymphatic DiseaseAcquired Patient Factors Associated with Pulmonary Vascular DiseaseDiagnostic Testing for Pulmonary Vascular Disease. Non-invasive Testing Age Focus: Pediatric Pulmonary Vascular Disease Fresh or Filed Publication: Fresh (PHresh). Less than 1-2 years since publication

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A Rare Phenotype of X-linked Myotubular Myopathy: Hydrops Fetalis and Refractory Congenital Chylothorax with Fatal Outcome

Chousein Amet, Umut Altunoglu, Süleyman Bayraktar, Bilge Bayraktar TanyeriBiruni University. Koç University. Haseki Training and Research Hospital.Turkey Zeitschrift für Geburtshilfe und NeonatologieZ Geburtshilfe Neonatol 2026; DOI: 10.1055/a-2825-7263 AbstractAbstract Not Available CategoryPrimary Pulmonary Lymphatic DiseaseGenetic Factors Associated with Pulmonary Vascular Disease Age Focus: Pediatric Pulmonary Vascular Disease Fresh or Filed Publication: Fresh (PHresh). Less than 1-2 years

A Rare Phenotype of X-linked Myotubular Myopathy: Hydrops Fetalis and Refractory Congenital Chylothorax with Fatal Outcome Read More »

Thoracic Duct Embolization in a Case of Congenital Chylothorax

Esin Gizem Olgun, Seyhan Celik Mertese, Arzu Meltem Demir, Secahattin Bayav, Serpil Ozdemir, Mukaddes Agirtici, Zarife Kuloglu, Semra Kucuk, Ozturk, Ceyda Tuna Kirsaclioglu, Aydan Kansu, Sadik Bilgic, Nazan CobanogluAnkara University Faculty of Medicine. Turkey Pediatric PulmonologyPediatr Pulmonol 2026; 61: DOI: 10.1002/ppul.71516 AbstractAbstract Not Available CategoryPrimary Pulmonary Lymphatic DiseaseSurgical and Catheter-mediated Interventions for Pulmonary Vascular Disease Age

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