Pediatric Pulmonary Vascular Disease

Etiologies of Pulmonary Arterial Hypertension in Early Infants: A 4-year Experience from a Tertiary Care Center in Southern India

Ysphaneendra Mallimoggala, Monalisa Biswas, Nitin Thyagaraja, H. Koushik, Krishnananda Nayak, Shrikiran Aroor, Varashree Bolar Suryakanth, Leslie LewisKasturba Medical College of Manipal Academy of Higher Education, Manipal College of Health Professionals and National Institute of Mental Health and Neuro Sciences. India Annals of African MedicineAnn Afr Med 2026; DOI: 10.4103/aam.aam_555_26 AbstractIntroduction: Pulmonary arterial hypertension (PAH) is relatively uncommon […]

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Mapping the evolving landscape: a bibliometric analysis of macrophages research in bronchopulmonary dysplasia (1990-2025)-a Web of Science Core Collection-based study

Hanzhou Guan, Huaiqing YinChildren’s Hospital Affiliated to Shanxi Medical University and First Hospital of Shanxi Medical University.China Translational PediatricsTransl Pediatr 2026; DOI: 10.21037/tp-2026-0236 AbstractBackground: Bronchopulmonary dysplasia (BPD) remains a major complication of prematurity, and macrophages are increasingly recognized as important drivers of lung injury and repair. We therefore performed a bibliometric analysis to map research trends, key

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Impact of Thermodilution on Indexed Pulmonary Vascular Resistance Calculations in Pediatric Pulmonary Arterial Hypertension

Daiji Takajo, Paul J. Critser, Russel HirschCincinnati Children’s Hospital Medical Center and University of Cincinnati.United States Pediatric PulmonologyPediatr Pulmonol 2026; 61:DOI: 10.1002/ppul.71787 AbstractBackground: Accurate assessment of pulmonary vascular resistance index (PVRi) is essential for the diagnosis and management of pulmonary arterial hypertension (PAH). PVRi depends on pulmonary blood flow (Qp), which can be determined by thermodilution or

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Congenital diaphragmatic hernia: a comprehensive review of pathogenesis, genetics, clinical features, and risk stratification

Esma Karadeniz-Gungormez, İbrahim Baytar, Betul B. Ozbal, Namik E. Akcan, Mustafa AzizogluBasaksehir Çam and Sakura City Hospital. Bursa City Hospital. Istinye University. Turkey Cirugia y CirujanosCir Cir 2026; DOI: 10.24875/CIRU.26000144 AbstractCongenital diaphragmatic hernia (CDH) is a rare and complex developmental disorder characterized by diaphragmatic defects, pulmonary hypoplasia, and persistent pulmonary hypertension, leading to significant neonatal morbidity

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Efficacy, Safety, and Pharmacokinetics of Macitentan in Japanese Pediatric Patients With Pulmonary Arterial Hypertension: Prospective, Multicenter, Open-Label Study

Ryo Inuzuka, Taku Ishii, Toru Iwasa, Kenichi Kurosaki, Ayako Kuraoka, Jun Narita, Shinichi Takatsuki, Masayoshi Nakano, Rieko Inagaki, Maki Mihoya, Kim Hyunsoo, Minaka Shibuya, Tohru Kobayashi, Hidekazu Ishida, Taichi Kato, Masaru Miura, Hiroyuki Yamagishi, Shozaburo DoiUniversity of Tokyo. Institute of Science Tokyo Hospital. National Cerebral and Cardiovascular Center. Fukuoka Children’s Hospital. University of Osaka Graduate

Efficacy, Safety, and Pharmacokinetics of Macitentan in Japanese Pediatric Patients With Pulmonary Arterial Hypertension: Prospective, Multicenter, Open-Label Study Read More »

Pediatric cardiomyopathy in a resource-limited setting: clinical characteristics and determinants of medium-term outcomes

Ghina Fakhri, Rana Zareef, Nour Younis, Nour Abdul Halim, Jad Abdul Khalek, Adham Makarem, Rand Ibrahim, Mohammed Ahmed, Fadi Fuad Bitar, Mariam Toufic ArabiAmerican University of Beirut Medical Center. American University of Beirut. Lebanon Frontiers in MedicineFront Med 2026; 13: DOI: 10.3389/fmed.2026.1800984 AbstractBackground and aims: Pediatric cardiomyopathy is the leading indication for cardiac transplantation in children. However,

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The Pediatric Pulmonary Hypertension International Risk Score: A Prediction Model for Outcomes Using Machine Learning

Megan Griffiths, Bhargava K. Chinni, Chantel Lokhorst, Johannes M. Douwes, Lynn A. Sleeper, Jennifer Tingo, Steven H. Abman, Erika B. Rosenzweig, Jennifer E. Schramm, Eric D. Austin, Mary P. Mullen, Alba Torrent-Vernetta, Carlos Labrandero, Raymond Benza, Maria Jesus del Cerro, Rolf M. F. Berger, Cedric Manlhiot, Allen D. EverettUT Southwestern Medical Center. Johns Hopkins University.

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Transcatheter atrial flow regulator implantation in children with pulmonary arterial hypertension in resource-limited settings: a single-centre experience

Bibhuti Das, Shreesha Maiya, Basha Khan, Vimal Raj, Shashi RajMethodist Children’s Hospital. Narayana Institute of Cardiac Sciences. United States and India Cardiology in the YoungCardiol Young 2026; DOI: 10.1017/S1047951126123555 AbstractPulmonary arterial hypertension in children remains a progressive disease marked by right ventricular failure and early mortality despite advances in targeted therapy. In resource-limited settings, access to

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Pulmonary Hypertension with a High-Output Hemodynamic Profile in a Child with MELAS: A Case Report

Miki Kanai, Hirofumi Tsuru, Takanori Onuki, Shunsuke Nukaga, Shigehito Baba, Masanori Tsukada, Tadaaki Abe, Fujito Numano, Kei Murayama, Akihiko SaitohSaiseikai Niigata Kenoh Kikan Hospital. Niigata University School of Medicine. Juntendo University. Japan Internal MedicineIntern Med 2026; DOI: 10.2169/internalmedicine.7614-26 AbstractPulmonary hypertension (PH) is uncommon in myopathy, encephalopathy, lactic acidosis, and stroke-like (MELAS) and its hemodynamics are poorly

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Pulmonary hypertension and acute hypoxic respiratory failure in preterm neonates

Marwa M. Elgendy, Sfurti NathUniversity of Maryland School of Medicine. Warren Alpert Medical School of Brown University.United States Journal of PerinatologyJ Perinatol 2026; DOI: 10.1038/s41372-026-02858-9 AbstractPulmonary hypertension (PH) in preterm infants is a complex and heterogeneous condition that significantly contributes to hypoxic respiratory failure (HRF), bronchopulmonary dysplasia (BPD), and mortality. Unlike term infants, PH in preterm

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