Potential Biomarkers Associated with Pulmonary Vascular Disease

QT dispersion and T wave peak-to-end in pediatric patients with sickle cell disease

Hanaa H. Eldash, Rana Mostafa, Heba A. BorayekFayoum University.Egypt Journal of ElectrocardiologyJ Electrocardiol 2025; DOI: 10.1016/j.jelectrocard.2025.154059 AbstractAim: The aim of the study was to detect cardiac repolarization changes and the risk of arrhythmias in children with sickle cell disease (SCD) and sickle thalassemia using echocardiography and electrocardiography (ECG).Methods: This is an observational case-control study that compared 20 patients […]

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Persistent Pulmonary Hypertension of the Newborn in Very Low Birth Weight Infants: Risk Factors and Clinical Outcomes from a Matched Case-Control Study

Anucha Thatrimontrichai, Pattima Pakhathirathien, Manapat Praditaukrit, Gunlawadee Maneenil, Supaporn Dissaneevate, Ploypailin Jantarawongpisal, Jenjira SaechanPrince of Songkla University.Thailand Journal of Clinical MedicineJ Clin Med 2025; 14: DOI: 10.3390/jcm14134759 AbstractBackground/Objectives: To identify the risk factors and clinical outcomes of persistent pulmonary hypertension of the newborn (PPHN) in very low birth weight (VLBW) infants in a resource-limited setting. Methods: We

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Mortality Risk Factors and Survival Outcomes in Infants with Persistent Pulmonary Hypertension of the Newborn

Kokaew Chuaikaew, Gunlawadee Maneenil, Anucha Thatrimontrichai, Supaporn Dissaneevate, Manapat PraditaukritPrince of Songkla University.Thailand Journal of Clinical MedicineJ Clin Med 2025; 14: DOI: 10.3390/jcm14134502 AbstractBackground/Objectives: Persistent pulmonary hypertension of the newborn (PPHN) is characterized by increased pulmonary vascular resistance, resulting in severe hypoxemia. This study determined the factors associated with increased risk of mortality and survival rate

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Proteomic characterization of type I collagen N-terminal crosslinked peptides

Zsuzsanna Darula, Maxwell C. McCabe, Alex Barrett, Lauren R. Schmitt, Mark D. Maslanka, Anthony J Saviola, Joseph Orgel, Alma Burlingame, Claudia A. Staab-Weijnitz, Kurt Stenmark, Valerie Weaver, Robert J. Chalkley, Kirk C. HansenHungarian Centre of Excellence for Molecular Medicine. HUN-REN Biological Research Centre. University of Colorado Denver, Anschutz Medical Campus. Illinois Institute of Technology. University

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Dysregulated Tricarboxylic Acid Cycle Metabolism Is Associated With Right Ventricular Maladaptation in Pulmonary Vascular Disease

Darin T. Rosen, Todd M. Kolb, Stephen C. Mathai, Karthik Suresh, Rachel Damico, Steven Hsu, Ryan J. Tedford, Anna R. Hemnes, Jane A. Leopold, Evelyn M. Horn, Erika S. Berman‐Rosenzweig, Franz Rischard, Robert P. Frantz, Serpil C. Erzurum, Gerald J. Beck, Nicholas S. Hill, John Barnard, Samar Farha, Gabriele Grunig, Christine Jellis, Deborah H. Kwon, Reena Mehra, Margaret M. Park, W. H. Wilson Tang, Paul M. Hassoun, Catherine E. Simpson, the PVDOMICS Study GroupJohns Hopkins University. University of Miami, Medical University of South Carolina. Vanderbilt University. Brigham and Women’s Hospital. Cornell University Medical Center. Westchester Medical Center and New

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Group D of pulmonary arterial hypertension and its relationship to congenital heart disease: Is there a non-invasive way to predict the unpredictable?

Antoine Fakhry AbdelMassih, Alyaa AlAli, Emad Nasr, Eman Hanafy, Musaab RamsiCairo University. heikh Khalifa Medical City and Pure Health Group. Aswan Heart Centre. Helwan University. Egypt and United Arab Emirates Global Cardiology Science and PracticeGlob Cardiol Sci Pract 2025; DOI: 10.21542/gcsp.2025.5 AbstractPulmonary arterial hypertension related to congenital heart disease (PAH-CHD), can pose a few challenging therapeutic

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Risk factors for severe pertussis in children and the application of exchange transfusion

Qihong Chen, Lihua Lin, Shuping Xiong, DandanGe, Yungang YangFirst Affiliated Hospital of Xiamen University, School of Medicine, Xiamen University. Pediatric Key Laboratory of Xiamen. Pediatric Quality Control Center of Xiamen. China Pediatric ResearchPediatr Res 2025; DOI: 10.1038/s41390-025-04118-6 AbstractObjective: To identify risk factors for severe pertussis and assess the efficacy of exchange transfusion in children.Methods: We analyzed pediatric pertussis

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BMPR-II, caspase-3, HIF-1α, and VE-cadherin profile in Down syndrome children with and without congenital heart disease and pulmonary hypertension

Sri L. Widjaja, Masayu L. Anniazi, Bagus Artiko, Annang G. Moelyo, Mylco T. AhmadwirawanUniversitas Sebelas Maret. Indonesia Narra JNarra J 2025; 5: DOI: 10.52225/narra.v5i1.1244 AbstractSeveral cellular markers have been identified as effective in detecting vascular remodeling recently. The reduced activity of bone morphogenetic protein receptor type-II (BMPR-II), commonly observed in Down syndrome, results in insufficient production

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Vasculopathy among children and adolescents with sickle cell disease: the crosstalk with annexin A1, vitamin D, and myocardial iron overload

Mohsen Saleh ElAlfy, Eman Abdel Rahman Ismail, Sara Mostafa Makkeyah, Ahmed Samir, Dina Husseiny Salama, Nanis Mohammed Salah Eldin, Dina Mohamed Fathy ElMaghraby, Nada Ayman Gad, Marwa Fath Ahmed Ali, Fatma Soliman El-Sayed EbeidAin Shams University. National Centre for Radiation Research and Technology, Egyptian Atomic Energy Authority. Minia UniversityEgypt Expert Review of HematologyExpert Rev Hematol

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Circulating Intercellular Adhesion Molecule as a Novel Marker of Pulmonary Hypertension in Newborn

Antoine Fakhry AbdelMassih, Sherif ElAnwary, Nourhan Taha, Noha Radwan, Mahmoud Othman AbouDeifCairo University Children Hospital and Cairo University. Sheikh Khalifa Medical City. Egypt and United Arab Emirates Indian PediatricsIndian Pediatr 2025;DOI: 10.1007/s13312-025-00037-1 AbstractBackground: IntercellularAQ1 adhesion molecules (ICAMs) are released from the endothelium in response to shear stress. Their role in persistent pulmonary hypertension (PPHN) remains un-investigated.Methodology: Sixty neonates

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