Potential Biomarkers Associated with Pulmonary Vascular Disease

[Association between adverse outcomes during hospitalization and early postnatal weight changes in term appropriate-for-gestational-age infants with early-onset sepsis]

Shi-Cheng Zeng, Xian-Lu Zhou, Ling-Ling Xiang, Zi-Yu HuaChildren’s Hospital of Chongqing Medical University, National Clinical Research Center for Child Health and Disorders, Ministry of Education Key Laboratory of Child Development and Disorders, and Chongqing Key Laboratory of Pediatric Metabolism and Inflammatory DiseasesChina Chinese Journal of Contemporary PediatricsZhongguo Dang Dai Er Ke Za Zhi 2026; 28: […]

[Association between adverse outcomes during hospitalization and early postnatal weight changes in term appropriate-for-gestational-age infants with early-onset sepsis] Read More »

Metabolomics of Right Ventricular Function in Pulmonary Hypertension

Jonathan Chacon-Barahona, Samuel J Chung, Jonah D Garry, Robert Frantz, Franz Rischard, Paul M Hassoun, Stephen C Mathai, Catherine E Simpson, Gerald Beck, Nicholas S Hill, Jane A Leopold, Aaron B Waxman, Erika B Rosenzweig, Barry A Borlaug, Monica Mukherjee, Rebecca Vanderpool, Miriam Jacob, Reena Mehra, Margaret M Park, J Emanuel Finet, Samar Farha, Gabriele Grunig, Deborah Kwon, Suzy Comhair, Serpil Erzurum, John Barnard, Bo Hu, Christine L Jellis, Alexandra Christin Racanelli, Jan Krumsiek, Evan L Brittain, Anna Hemnes, Evelyn Horn; PVDOMICS Study GroupWeill Cornell Medical College. Albert

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Identification of RUNX1 as a Biomarker for Right Ventricular Remodeling in Pulmonary Arterial Hypertension Using WGCNA

Wenjie Chen, Min Peng, Yusi Chen, Jun Luo, Jingyuan Chen, Haihua Qiu, Jiang LiSecond Xiangya Hospital of Central South University. Third Xiangya Hospital Central South University.China Pulmonary CirculationPulm Circ 2026; 16: DOI: 10.1002/pul2.70297 AbstractRight ventricle (RV) dysfunction is central to pulmonary arterial hypertension (PAH) yet its molecular mechanisms remain unclear. This study aimed to identify biomarkers

Identification of RUNX1 as a Biomarker for Right Ventricular Remodeling in Pulmonary Arterial Hypertension Using WGCNA Read More »

Alternative Polyadenylation Signatures Distinguish Maladaptive Right Ventricular Remodeling in Pulmonary Hypertension: Implications for RNA-Based Diagnostics and Therapeutics

Janani Subramaniam, Venkata Jonnakuti, Scott D. Collum, Sandra Martineau, Kai-Lieh Huang, Sandra Breuils-Bonnet, Andrea L. Frump, Bindu H. Akkanti, Jayeshkumar A. Patel, Manish K. Patel, Ismael Salas de Armas, Isabella N. Lefebvre, Rajko Radovancevic, Elvin Blanco, Eric J. Wagner, Igor Gregoric, Sriram Nathan, Biswajit Kar, Steeve Provencher, Sebastien Bonnet, François Potus, Hari Krishna Yalamanchili, Harry

Alternative Polyadenylation Signatures Distinguish Maladaptive Right Ventricular Remodeling in Pulmonary Hypertension: Implications for RNA-Based Diagnostics and Therapeutics Read More »

A circulating MicroRNA signature for the diagnosis of pulmonary arterial hypertension and functional characterization of candidate miR-3168

Mauro Lago-Docampo, Ainhoa Iglesias-López, Carlos Vilariño, Adolfo Baloira, Joan Albert Barberá, Isabel Blanco, Diana ValverdeUniversidade de Vigo. Galicia Sur Health Research Institute. Hospital Povisa. Complejo Hospitalario Universitario de Pontevedra. University of Barcelona. Stanford University School of Medicine.Spain and United States Scientific ReportsSci Rep 2026; DOI: 10.1038/s41598-026-42550-8 AbstractPulmonary Arterial Hypertension (PAH) is a rare, progressive disorder characterized

A circulating MicroRNA signature for the diagnosis of pulmonary arterial hypertension and functional characterization of candidate miR-3168 Read More »

Association Between Hemodynamic Parameters and Gut Microbiota in Fontan Circulation: A Cross-Sectional Study

Saviga Sethasathien, Chanon Kunasol, Suchaya Silvilairat, Rekwan Sittiwangkul, Pannipa Suwannasom, Nipon Chattipakorn, Krit Leemasawat, Siriporn C. ChattipakornChiang Mai University. Thailand Journal of the American Heart AssociationJ Am Heart Assoc 2026; DOI: 10.1161/JAHA.125.045962 AbstractBackground: The Fontan operation results in chronic hemodynamic alterations, including central venous hypertension, which may contribute to gut dysbiosis. This study aimed to compare gut

Association Between Hemodynamic Parameters and Gut Microbiota in Fontan Circulation: A Cross-Sectional Study Read More »

A Novel Rat Model for Group 2 Pulmonary Hypertension by Total Pulmonary Vein Banding: Multi-Omics Insights into Pathophysiological Mechanisms

Jin Shentu, Wenxuan Dai, Chang Chen, Jiawei Huang, Lijun Chen, Yi Yan, Han Zhang, Zhongqun Zhu, Guocheng Shi, Huiwen ChenShanghai Children’s Medical Center and Shanghai Jiao Tong University School of Medicine. China Journal of Thoracic and Cardiovascular SurgeryJ Thorac Cardiovasc Surg 2026; DOI: 10.1016/j.jtcvs.2026.01.017 AbstractObjectives: Group 2 pulmonary hypertension (PH) remains a highly morbid disease, yet no

A Novel Rat Model for Group 2 Pulmonary Hypertension by Total Pulmonary Vein Banding: Multi-Omics Insights into Pathophysiological Mechanisms Read More »

Microbiome-Metabolome Axis in BALF Reveals Novel Diagnostic Biomarkers for Congenital Heart Disease-Associated Pulmonary Arterial Hypertension

Xiaoyu Zhang, Liming Cheng, Yuan Zhou, Jiahui Xie, Wenting Gui, Jiaxiang Chen, Zidan Zhang, Kai Liu, Runwei MaFuwai Yunnan Hospital, Chinese Academy of Medical Sciences, Affiliated Cardiovascular Hospital of Kunming Medical University. Kunming Children’s Hospital.China Journal of Cardiovascular Development and DiseaseJ Cardiovasc Dev Dis 2026; 13: DOI: 10.3390/jcdd13010032 AbstractBackground: Early identification of irreversible pulmonary vascular remodeling in

Microbiome-Metabolome Axis in BALF Reveals Novel Diagnostic Biomarkers for Congenital Heart Disease-Associated Pulmonary Arterial Hypertension Read More »

Mean corpuscular haemoglobin concentration (MCHC): a new biomarker for high-altitude pulmonary edema in the Ecuadorian Andes

Karen Sánchez, Lenin Ramírez‑Cando, Wilfre Machado, AnitaVillafuerte, Santiago BallazYachay University for Experimental Technology and Research. Hospital Claudio Benati. Universidad Espíritu Santo.Ecuador Scientific ReportsSci Rep 2022; 12: DOI: 10.1038/s41598-022-25040-5 AbstractAscent to high altitude (> 3000 m height above sea level or m.a.s.l) exposes people to hypobaric atmospheric pressure and hypoxemia, which provokes mountain sickness and whose symptoms

Mean corpuscular haemoglobin concentration (MCHC): a new biomarker for high-altitude pulmonary edema in the Ecuadorian Andes Read More »

Pulmonary hypertension in pediatric patients with cystic fibrosis during acute pulmonary exacerbations: prevalence and associated factors

Zahra Roshanzamir, Fatemeh Mohammadi, Rohola ShirzadiNamazi Hospital and Shiraz University of Medical Sciences. Children’s Medical Center and Tehran University of Medical Sciences.Iran BioMedical Central Pulmonary MedicineBMC Pulm Med 2026; DOI: 10.1186/s12890-025-04095-w AbstractBackground: Cystic fibrosis (CF) is a multi-organ disorder in which respiratory complications account for the majority of its cause of mortality. This study aimed to investigate

Pulmonary hypertension in pediatric patients with cystic fibrosis during acute pulmonary exacerbations: prevalence and associated factors Read More »

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