Potential Biomarkers Associated with Pulmonary Vascular Disease

Risk factors for severe pertussis in children and the application of exchange transfusion

Qihong Chen, Lihua Lin, Shuping Xiong, DandanGe, Yungang YangFirst Affiliated Hospital of Xiamen University, School of Medicine, Xiamen University. Pediatric Key Laboratory of Xiamen. Pediatric Quality Control Center of Xiamen. China Pediatric ResearchPediatr Res 2025; DOI: 10.1038/s41390-025-04118-6 AbstractObjective: To identify risk factors for severe pertussis and assess the efficacy of exchange transfusion in children.Methods: We analyzed pediatric pertussis […]

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BMPR-II, caspase-3, HIF-1α, and VE-cadherin profile in Down syndrome children with and without congenital heart disease and pulmonary hypertension

Sri L. Widjaja, Masayu L. Anniazi, Bagus Artiko, Annang G. Moelyo, Mylco T. AhmadwirawanUniversitas Sebelas Maret. Indonesia Narra JNarra J 2025; 5: DOI: 10.52225/narra.v5i1.1244 AbstractSeveral cellular markers have been identified as effective in detecting vascular remodeling recently. The reduced activity of bone morphogenetic protein receptor type-II (BMPR-II), commonly observed in Down syndrome, results in insufficient production

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Vasculopathy among children and adolescents with sickle cell disease: the crosstalk with annexin A1, vitamin D, and myocardial iron overload

Mohsen Saleh ElAlfy, Eman Abdel Rahman Ismail, Sara Mostafa Makkeyah, Ahmed Samir, Dina Husseiny Salama, Nanis Mohammed Salah Eldin, Dina Mohamed Fathy ElMaghraby, Nada Ayman Gad, Marwa Fath Ahmed Ali, Fatma Soliman El-Sayed EbeidAin Shams University. National Centre for Radiation Research and Technology, Egyptian Atomic Energy Authority. Minia UniversityEgypt Expert Review of HematologyExpert Rev Hematol

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Circulating Intercellular Adhesion Molecule as a Novel Marker of Pulmonary Hypertension in Newborn

Antoine Fakhry AbdelMassih, Sherif ElAnwary, Nourhan Taha, Noha Radwan, Mahmoud Othman AbouDeifCairo University Children Hospital and Cairo University. Sheikh Khalifa Medical City. Egypt and United Arab Emirates Indian PediatricsIndian Pediatr 2025;DOI: 10.1007/s13312-025-00037-1 AbstractBackground: IntercellularAQ1 adhesion molecules (ICAMs) are released from the endothelium in response to shear stress. Their role in persistent pulmonary hypertension (PPHN) remains un-investigated.Methodology: Sixty neonates

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Pediatric Pulmonary Hypertension is Associated With Increased Circulating Levels of BMP 7 and CHIP

Edward C. Kirkpatrick, Stephanie Handler, Melodee Liegl, Amy Y. Pan, G. Ganesh Konduri, Todd M. Gudausky, Adeleye J. AfolayanChildren’s Wisconsin and Medical College of Wisconsin.United States Pulmonary CirculationPulm Circ 2024; 15: DOI: 10.1002/pul2.70068 AbstractPulmonary arterial endothelial and smooth muscle cell homeostasis is regulated through the bone morphogenetic protein (BMP) and transforming growth factor beta (TGF-β) receptor

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Cellular Communication Network Protein 2 in the Right Ventricle of Pulmonary Arterial Hypertension

Carly E. Byrd, Jennifer E. Schramm, Jun Yang, Allan E. Barnes, Megan Griffiths, Anjira S. Ambade, Darin T. Rosen, Ilton M. Cubero Salazar, Catherine E. Simpson, Ryan J. Tedford, Steven Hsu, Dhananjay Vaidya, Todd M. Kolb, Michael W. Pauciulo, William C. Nichols, David D. Ivy, Eric D. Austin, Paul M. Hassoun, Rachel L. Damico, Allen

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Increased circulating Endothelin-1 is a risk factor for ECMO use and mortality in neonates with congenital diaphragmatic hernia: a prospective observational study

Lotte Lemloh, Aster de Vadder, Tamene Melaku, Bartolomeo Bo, Neil Patel, Stefan Holdenrieder, Andreas Mueller, Florian KipfmuellerChildren’s Hospital, University of Bonn. Royal Hospital for Children. Technical University of Munich. University Medical Center Mannheim, University of Heidelberg.Germany and United Kingdom Respiratory ResearchRespir Res 2025; 25: DOI: 10.1186/s12931-025-03188-8 AbstractBackground: Elevated levels of Endothelin-1 (ET-1), a vasoactive peptide, have been

Increased circulating Endothelin-1 is a risk factor for ECMO use and mortality in neonates with congenital diaphragmatic hernia: a prospective observational study Read More »

Increased Endothelin-1 Is Associated With Morbidity in Single Ventricle Heart Disease in Children Undergoing Fontan Palliation

Benjamin S. Frank, Sierra Niemiec, Ludmila Khailova, Christopher A. Mancuso, Max B. Mitchell, Gareth J. Morgan, Mark Twite, Michael V. DiMaria, Carmen C. Sucharov, Jesse A. DavidsonUniversity of Colorado. University of Michigan.United States Journal of the American College of Cardiology AdvancesJACC Adv 2025; 4: DOI: 10.1016/j.jacadv.2025.101672 AbstractBackground: Endothelin-1 (ET1) is a potent vasoconstrictor and stimulator of pulmonary

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Corrigendum to “Relationship Between Urine Serotonin and Persistent Pulmonary Hypertension of the Newborn”. J Pediatr 2025; 276:114290

Jamie L. Archambault, Teri L. Hernandez, Eva S. Nozik, Claire Palmer, Mairead Dillon, Ravinder J. Singh, Csaba Galambos, Cassidy A. DelaneyUniversity of Colorado. Mayo Clinic College of Medicine. United States Journal of PediatricsJ Pediatr 2025; DOI: 10.1016/j.jpeds.2025.114462 AbstractAbstract Not Available CategoryClass I. Persistent Pulmonary Hypertension of the NewbornAcquired Patient Factors Associated with Pulmonary Vascular DiseasePotential Biomarkers

Corrigendum to “Relationship Between Urine Serotonin and Persistent Pulmonary Hypertension of the Newborn”. J Pediatr 2025; 276:114290 Read More »

Anti-fibroblast and anti-endothelial cell autoantibodies in pulmonary arterial hypertension (PAH) in patients with connective tissue diseases (CTD)

Benjamin Thoreau, Arthur Ranaud, Philippe Chafey, Guilhem Clary, Morgane La Gall, Cédric Broussard, Odile Launay, David Launay, Eric Hachulla, Christophe Deligny, Alban-Elouen Baruteau, Anaïs Vallet-Pichard, Benjamin Chaigne, Azzeddine Yaici, Oliver Sitbon, David Montani, Marc Humbert, Luc MouthonUniversité Paris Cité. Hôpital Cochin and Assistance Publique-Hôpitaux de Pari. de l’Est et de l’Ouest. Hôpital Pierre Zobda-Quitman. Nantes

Anti-fibroblast and anti-endothelial cell autoantibodies in pulmonary arterial hypertension (PAH) in patients with connective tissue diseases (CTD) Read More »

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