Class 3. Pulmonary Hypertension Associated with Lung Hypoplasia

Congenital diaphragmatic hernia: a comprehensive review of pathogenesis, genetics, clinical features, and risk stratification

Esma Karadeniz-Gungormez, İbrahim Baytar, Betul B. Ozbal, Namik E. Akcan, Mustafa AzizogluBasaksehir Çam and Sakura City Hospital. Bursa City Hospital. Istinye University. Turkey Cirugia y CirujanosCir Cir 2026; DOI: 10.24875/CIRU.26000144 AbstractCongenital diaphragmatic hernia (CDH) is a rare and complex developmental disorder characterized by diaphragmatic defects, pulmonary hypoplasia, and persistent pulmonary hypertension, leading to significant neonatal morbidity

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Pulmonary Hypoplasia

Aneesha Geraghty, Patrick Smith, Kristen Arnold, Paul S. KingmaUniversity of Cincinnati College of Medicine and Cincinnati Children’s Hospital Medical Center.United States NeoReviewsNeoreviews 2026; 27: e511-e522DOI: 10.1542/neo.27-7-039 AbstractPulmonary hypoplasia is a rare but clinically significant congenital disorder characterized by impaired fetal lung development, leading to impaired growth and maturation of lung parenchyma and pulmonary vasculature. Stemming from

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Meta-analysis of prostacyclin therapy for persistent pulmonary hypertension with congenital diaphragmatic hernia

Shouliang Jiang, Xue Han, Yang He, Qian Gao, Juan Liang, Tingting Zhu, Li Zhang, Jun TangWest China Second University Hospital and Sichuan University. China Journal of Pediatric SurgeryJ Pediatr Surg 2026; DOI: 10.1016/j.jpedsurg.2026.163301 AbstractObjective: To evaluate the efficacy and safety of prostacyclin in the treatment of persistent pulmonary hypertension in congenital diaphragmatic hernia.Methods: A systematic literature search was

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Reduced KLF4 expression in endothelial cells triggers pulmonary vascular abnormalities associated with experimental congenital diaphragmatic hernia

Heleen M. Kool, Petra E. Bürgisser, Gabriela G. Edel, Anne Boerema-de Munck, Marjon Buscop-van Kempen, Panagiotis Liakopoulos, Petros Kolovos, Wilfred F. J. Ijcken, Robbert J. RottierSophia Children’s Hospital. Erasmus Medical Center. Democritus University of Thrace. Netherlands and Greece Cellular and Molecular Life SciencesCell Mol Life Sci 2026; DOI: 10.1007/s00018-026-06319-6 AbstractCongenital diaphragmatic hernia (CDH) is a rare

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Thoracoscopic Versus Open Repair of Congenital Diaphragmatic Hernia: A Retrospective Case Series From a Tertiary Care Center

Shishir Kumar, Ratan Kumar, Mrunalkant Panchal, Preeti Srivastava, Sanjay K. TantiTata Main Hospital, Manipal Tata Medical College and Manipal Academy of Higher Education.India CureusCureus 2026; 18: DOI: 10.7759/cureus.111125 AbstractBackground: Congenital diaphragmatic hernia (CDH) remains a challenging neonatal surgical condition associated with significant morbidity and mortality. Thoracoscopic repair has emerged as a minimally invasive alternative to conventional open

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Preliminary Report of a Nationwide Prospective Cohort of Congenital Diaphragmatic Hernia in Korea

Jiyoon Jeong, Byong Sop Lee, Hoseon Eun, Seung Han Shin, So Yoon Ahn, Shin Yun Byun, Eun Song Song, on behalf of the Korean Congenital Diaphragmatic Hernia CohortAsan Medical Center and University of Ulsan College of Medicine. Severance Hospital and Yonsei University College of Medicine. Seoul National University Hospital and Seoul National University College of

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Neonatal Survival After Serial Amnioinfusions for Anhydramnios Due to Fetal Kidney Failure: The RAFT Clinical Trial

Jena L. Miller, Ahmet A. Baschat, Anthony Johnson, Yair J. Blumenfeld, Mauro H. Schenone, Juliana S. Gebb, Julie S. Moldenhauer, Michael V. Zaretsky, Ramen H. Chmait, Juan M. Gonzalez, Russel S. Miller, Eyal Krispin, Alireza Shamshirsaz, Katherine H. Bligard, Amanda M. Kalan, Magdalena Sanz Cortes, Anita J. Moon-Grady, Ellen Bendel-Stenzel, Shina Menon, Cynthia Wong, Paul

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Prenatal and Postnatal Ultrasound Findings of Congenital Diaphragmatic Hernia Associated With Myelomeningocele, Chiari II Malformation, and Renal Dysplasia

Faith Isleyen, Muzeyyen KalkanSanliurfa Training and Research Hospital.Turkey Journal of Clinical UltrasoundJ Clin Ultrasound 2026; DOI: 10.1002/jcu.70326 AbstractCongenital diaphragmatic hernia (CDH) associated with neural tube defects is exceedingly rare. We report a female neonate (2550 g) born at 35 weeks (Apgar 2/4/5) with severe left-sided Bochdalek CDH, lumbosacral myelomeningocele, Chiari II malformation, and unilateral renal dysplasia.

Prenatal and Postnatal Ultrasound Findings of Congenital Diaphragmatic Hernia Associated With Myelomeningocele, Chiari II Malformation, and Renal Dysplasia Read More »

Cardiac performance and left ventricular dimensions in neonates with left-sided congenital diaphragmatic hernia before and after surgical repair

Mohamed Mahmoud Shalaby, Fatma Aboalsoud TahaTanta University.Egypt Journal of Cardiothoracic SurgeryJ Cardiothorac Surg 2026; DOI: 10.1186/s13019-026-04289-1 AbstractBackground: Congenital Diaphragmatic Hernia (CDH) is associated with significant cardiopulmonary morbidity. Pulmonary Hypertension (PH) and left ventricular (LV) dysfunction are major determinants of outcome. While the impact of CDH repair on pulmonary hemodynamics is recognized, comprehensive serial assessment of cardiac performance,

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Respiratory Management for the Infant with Congenital Diaphragmatic Hernia

Michelle J. Yang, Matthew Douglass, Ryan J. Carpenter, Bradley A. YoderUniversity of Utah School of Medicine and Primary Children’s Hospital.United States Clinics in PerinatologyClin Perinatol 2026; 53: 277-295DOI: 10.1016/j.clp.2026.02.002 AbstractCongenital diaphragmatic hernia (CDH) is a complex neonatal condition characterized by pulmonary hypoplasia and pulmonary hypertension, requiring specialized ventilatory management from birth through postoperative care. This article

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