Class 3. Pulmonary Hypertension Associated with Lung Hypoplasia

Reduced KLF4 expression in endothelial cells triggers pulmonary vascular abnormalities associated with experimental congenital diaphragmatic hernia

Heleen M. Kool, Petra E. Bürgisser, Gabriela G. Edel, Anne Boerema-de Munck, Marjon Buscop-van Kempen, Panagiotis Liakopoulos, Petros Kolovos, Wilfred F. J. Ijcken, Robbert J. RottierSophia Children’s Hospital. Erasmus Medical Center. Democritus University of Thrace. Netherlands and Greece Cellular and Molecular Life SciencesCell Mol Life Sci 2026; DOI: 10.1007/s00018-026-06319-6 AbstractCongenital diaphragmatic hernia (CDH) is a rare […]

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Thoracoscopic Versus Open Repair of Congenital Diaphragmatic Hernia: A Retrospective Case Series From a Tertiary Care Center

Shishir Kumar, Ratan Kumar, Mrunalkant Panchal, Preeti Srivastava, Sanjay K. TantiTata Main Hospital, Manipal Tata Medical College and Manipal Academy of Higher Education.India CureusCureus 2026; 18: DOI: 10.7759/cureus.111125 AbstractBackground: Congenital diaphragmatic hernia (CDH) remains a challenging neonatal surgical condition associated with significant morbidity and mortality. Thoracoscopic repair has emerged as a minimally invasive alternative to conventional open

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Preliminary Report of a Nationwide Prospective Cohort of Congenital Diaphragmatic Hernia in Korea

Jiyoon Jeong, Byong Sop Lee, Hoseon Eun, Seung Han Shin, So Yoon Ahn, Shin Yun Byun, Eun Song Song, on behalf of the Korean Congenital Diaphragmatic Hernia CohortAsan Medical Center and University of Ulsan College of Medicine. Severance Hospital and Yonsei University College of Medicine. Seoul National University Hospital and Seoul National University College of

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Neonatal Survival After Serial Amnioinfusions for Anhydramnios Due to Fetal Kidney Failure: The RAFT Clinical Trial

Jena L. Miller, Ahmet A. Baschat, Anthony Johnson, Yair J. Blumenfeld, Mauro H. Schenone, Juliana S. Gebb, Julie S. Moldenhauer, Michael V. Zaretsky, Ramen H. Chmait, Juan M. Gonzalez, Russel S. Miller, Eyal Krispin, Alireza Shamshirsaz, Katherine H. Bligard, Amanda M. Kalan, Magdalena Sanz Cortes, Anita J. Moon-Grady, Ellen Bendel-Stenzel, Shina Menon, Cynthia Wong, Paul

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Prenatal and Postnatal Ultrasound Findings of Congenital Diaphragmatic Hernia Associated With Myelomeningocele, Chiari II Malformation, and Renal Dysplasia

Faith Isleyen, Muzeyyen KalkanSanliurfa Training and Research Hospital.Turkey Journal of Clinical UltrasoundJ Clin Ultrasound 2026; DOI: 10.1002/jcu.70326 AbstractCongenital diaphragmatic hernia (CDH) associated with neural tube defects is exceedingly rare. We report a female neonate (2550 g) born at 35 weeks (Apgar 2/4/5) with severe left-sided Bochdalek CDH, lumbosacral myelomeningocele, Chiari II malformation, and unilateral renal dysplasia.

Prenatal and Postnatal Ultrasound Findings of Congenital Diaphragmatic Hernia Associated With Myelomeningocele, Chiari II Malformation, and Renal Dysplasia Read More »

Cardiac performance and left ventricular dimensions in neonates with left-sided congenital diaphragmatic hernia before and after surgical repair

Mohamed Mahmoud Shalaby, Fatma Aboalsoud TahaTanta University.Egypt Journal of Cardiothoracic SurgeryJ Cardiothorac Surg 2026; DOI: 10.1186/s13019-026-04289-1 AbstractBackground: Congenital Diaphragmatic Hernia (CDH) is associated with significant cardiopulmonary morbidity. Pulmonary Hypertension (PH) and left ventricular (LV) dysfunction are major determinants of outcome. While the impact of CDH repair on pulmonary hemodynamics is recognized, comprehensive serial assessment of cardiac performance,

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Respiratory Management for the Infant with Congenital Diaphragmatic Hernia

Michelle J. Yang, Matthew Douglass, Ryan J. Carpenter, Bradley A. YoderUniversity of Utah School of Medicine and Primary Children’s Hospital.United States Clinics in PerinatologyClin Perinatol 2026; 53: 277-295DOI: 10.1016/j.clp.2026.02.002 AbstractCongenital diaphragmatic hernia (CDH) is a complex neonatal condition characterized by pulmonary hypoplasia and pulmonary hypertension, requiring specialized ventilatory management from birth through postoperative care. This article

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Risk Stratification and Fetal Therapies for Congenital Diaphragmatic Hernia

Connor V. Haynes, David H. StitelmanYale New Haven Children’s Hospital,United States NeoreviewsNeoreviews 2026; DOI: 10.1542/neo.27-6-021 AbstractCongenital diaphragmatic hernia (CDH) remains one of the most challenging congenital anomalies encountered by neonatologists and pediatric surgeons, with outcomes largely determined before birth. Although surgical repair of the diaphragmatic defect is essential, postnatal morbidity and mortality are primarily driven by

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Breathing challenges in achondroplasia: a comprehensive review of pediatric respiratory complications

Veronica Fasoli, Alessia Mariani, Federica Chironi, Mara Lelii, Barbara Madini, Beatrice Andrenacci, Alessia Rocchi, M. Francesca Bedeschi, M. Gaffuri, M. Pluderi, M. Francesca PatriaUniversità Degli Studi di Milano. Fondazione IRCCS Ca’ Granda Ospedale Maggiore Policlinico. Italy Paediatric Respiratory ReviewsPaediatr Respir Rev 2026; DOI: 10.1016/j.prrv.2026.05.003 AbstractAchondroplasia is the most common skeletal dysplasia, characterized by disproportionate short stature

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Prenatal Assessment of Diaphragmatic Defect Size in Left-Sided Congenital Diaphragmatic Hernia Using a Novel MRI-based Parameter for Outcome Prediction: The Defect-to-HEmithorax Ratio (DHER)

Chiara Panunzi, Sara Savelli, Laura Valfré, Irma Capolupo, Milena Viggiano, Chiara Vassallo, Andrea Conforti, Leonardo Caforio, Isabella FabiettiBambino Gesù Children’s Hospital, IRCCS and Università degli Studi di Pavia. Italy American Journal of Obstetrics and Gynecology Maternal Fetal MedicineAm J Obstet Gynecol MFM 2026; DOI: 10.1016/j.ajogmf.2026.102002 AbstractBackground: In congenital diaphragmatic hernia (CDH), the size of the diaphragmatic defect

Prenatal Assessment of Diaphragmatic Defect Size in Left-Sided Congenital Diaphragmatic Hernia Using a Novel MRI-based Parameter for Outcome Prediction: The Defect-to-HEmithorax Ratio (DHER) Read More »

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