Class 3. Pulmonary Hypertension Associated with Lung Hypoplasia

Early postnatal echocardiographic characteristics impact survival and extracorporeal life support in congenital diaphragmatic hernia

Caroline Y. Noh, Enrico Danzer, Shazia Bhombal, Valerie Y. Chock, Neil Patel, Alex Dahlen, Matthew T. Harting, Kevin P. Lally, Ashley H. Ebanks, Krisa P. Van Meurs, Congenital Diaphragmatic Hernia Study GroupChildren’s Hospital Los Angeles and University of Southern California Keck School of Medicine. Stanford University School of Medicine and Lucile Packard Children’s Hospital. Memorial […]

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Pharmacology in Congenital Diaphragmatic Hernia: A Focus on Cardiovascular Management

Anie Lapointe, Florian Kipfmueller, Neil Patel, Gabriel AltitCHU Sainte-Justine. University Medical Center Mannheim and University of Heidelberg. Royal Hospital for Children. Montreal Children’s Hospital and McGill University Health Centre Research Institute.Canada, Germany and United Kingdom NeoreviewsNeoreviews 2025; 26: e660-e678DOI: 10.1542/neo.26-10-060 AbstractCongenital diaphragmatic hernia (CDH) presents a complex challenge in neonatal care, requiring tailored pharmacological strategies to

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Antenatal Sildenafil for Congenital Diaphragmatic Hernia: A Systematic Review and Bayesian Meta-Analysis of Preclinical Studies

Tamara M. Hundscheid, Ilaria Amodeo, Giacomo Cavallaro, Carlijn R. Hooijmans, František Bartoš, Eduardo VillamorMosaKids Children’s Hospital and Maastricht University Medical Center. Clínica Universidad de Navarra. Fondazione IRCCS Ca’ Granda Ospedale Maggiore Policlinico. Radboud University Medical Center. University of Amsterdam.Netherlands, Spain and Italy BiomedicinesBiomed 2025; 13: DOI: 10.3390/biomedicines13092274 AbstractBackground: In congenital diaphragmatic hernia (CDH), pulmonary hypoplasia and

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Indication, technical considerations, and outcome of remote central cannulation for repeat extracorporeal membrane oxygenation in congenital diaphragmatic hernia: a case report

Enrico Danzer, Sabrina J. Flohr, Holly L. Hedrick, Geoffrey L. Bird, Jonathan M. Chen, Natalie E. RintoulChildren’s Hospital of Philadelphia. United States Journal of ExtraCorporeal TechnologyJ Extra Corpor Technol 2025; 57: 168-170DOI: 10.1051/ject/2025019 AbstractRepeat extracorporeal membrane oxygenation (ECMO) is rare in children with congenital diaphragmatic hernia (CDH). Improving our understanding of the potential survival benefits, complications,

Indication, technical considerations, and outcome of remote central cannulation for repeat extracorporeal membrane oxygenation in congenital diaphragmatic hernia: a case report Read More »

Pulmonary Hypertension Outcomes After Closure of Atrial Septal Defect in Infants With Developmental Lung Disease

John L. Wiegand, James A. Thompson, Bruce F. Landeck, Jamie L. Fierstein, Dina Ashour, Joana S. Machry, Amy L. Kiskaddon, Marisol Betensky, Grace A. FreireUniversity of South Florida Morsani College of Medicine. Johns Hopkins All Children’s Hospital. United States Pulmonary CirculationPulm Circ 2025; 15: DOI: 10.1002/pul2.70164 AbstractPulmonary hypertension (PHTN) in infants with developmental lung disease, such

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Optimizing ECLS strategies in the management of congenital diaphragmatic hernia: Recent advances and best practices

Kylie Holden, Devin Saljuud, Kevin Johnson, Matthew T. HartingMcGovern Medical School at the University of Texas Health Science Center. Vanderbilt University.United States Seminars in Fetal and Neonatal MedicineSemin Fetal Neonatal Med 2025; DOI: 10.1016/j.siny.2025.101659 AbstractInfants with congenital diaphragmatic hernia (CDH) face severe pulmonary hypoplasia, pulmonary hypertension, and cardiac dysfunction, making it one of the most challenging

Optimizing ECLS strategies in the management of congenital diaphragmatic hernia: Recent advances and best practices Read More »

Premature monozygotic twins with congenital diaphragmatic hernia: a case report

Muhammet Zahit Koyuncu, Ayşegül Aşkın, Hüseyin Altunhan, Nuriye Emiroğlu, Canan KocaoğluNecmettin Erbakan University. Turkey Sudanese Journal of PaediatricsSudan J Paediatr 2025; 25: 66-70DOI: 10.24911/SJP.106-1746615665 AbstractCongenital diaphragmatic hernia (CDH) is a severe developmental anomaly with variable clinical outcomes, influenced by factors such as liver herniation, pulmonary hypertension and associated anomalies. While familial clustering of CDH has been

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Outcomes for Congenital Diaphragmatic Hernia in Three Decades: A Report From a UK Surgical Centre

Wan Teng Lee, Paul D. LostyUniversity of Liverpool. Alder Hey Children’s Hospital Liverpool. Ramathibodi Hospital and Mahidol University.United Kingdom and Thailand Acta PaediatricaActa Paediatr 2025; DOI: 10.1111/apa.70295 AbstractAims: Congenital diaphragmatic hernia (CDH) is associated with lung hypoplasia, pulmonary hypertension and high mortality. Three decades experience from a UK centre is reported.Methods: Medical records of CDH newborns between February

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What is the role of echocardiography in newborns with CDH?

María V. Fraga, Gabriel Altit, Bradley A. Yoder, Shazia BhombalChildren’s Hospital of Philadelphia, Perelman School of Medicine and University of Pennsylvania. McGill University. University of Utah School of Medicine. Children’s Healthcare of Atlanta/Emory University.United States and Canada Seminars in Fetal and Neonatal MedicineSemin Fetal Neonatal Med 2025;DOI: 10.1016/j.siny.2025.101657 AbstractCongenital diaphragmatic hernia (CDH) is associated with high

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Fetal therapies in congenital diaphragmatic hernia: a review of possibilities and practical challenges

Adriana Dekirmendjian, Fabian Doktor, Lina Antounians, Augusto ZaniUniversity of Toronto and Hospital for Sick Children. St. Louis Children’s Hospital and Washington University. Canada and United States Seminars in Fetal and Neonatal MedicineSemin Fetal Neonatal Med 2025; DOI: 10.1016/j.siny.2025.101656 AbstractCongenital diaphragmatic hernia (CDH) is characterized by pulmonary hypoplasia. CDH lungs exhibit an inflammatory signature with impaired growth,

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