Pediatric Pulmonary Vascular Disease

Neurodevelopmental outcome in children between one and five years after persistent pulmonary hypertension of term and near-term newborns

Laetitia Atlan, Lionel Berthomieu, Caroline Karsenty, Géraldine Gascoin, Catherine Arnaud, Sophie BreinigUniversity Hospital and Toulouse III University.France Frontiers in PediatricsFront Pediatr 2024; 12: DOI: 10.3389/fped.2024.1450916 AbstractBackground: Persistent pulmonary hypertension of the newborn (PPHN) is a serious condition that affects 1-2 per 1,000 newborns. Scientific data report the existence of neurological developmental abnormalities between 10 and 30%, but […]

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microRNAs in Congenital Diaphragmatic Hernia: Insights into Prenatal and Perinatal Biomarkers and Altered Molecular Pathways: microRNAs in Congenital Diaphragmatic Hernia for Pathway Analysis and Prognostic Biomarkers

James R. Bardill, Anis Karimpour-Fard, Courtney C. Breckenfelder, Carmen C. Sucharov, Caitlin R. Eason, Lauren T. Gallagher, Ludmila Khailova, Clyde J. Wright, Jason Gien, Henry L. Galan, S. Christopher DerderianUniversity of Colorado School of Medicine and Children’s Hospital Colorado. United States American Journal of Obstetrics and Gynecology Maternal and Fetal MedicineAm J Obstet Gynecol MFM

microRNAs in Congenital Diaphragmatic Hernia: Insights into Prenatal and Perinatal Biomarkers and Altered Molecular Pathways: microRNAs in Congenital Diaphragmatic Hernia for Pathway Analysis and Prognostic Biomarkers Read More »

Utility of Serum Matrix Metalloproteinase-7 as a Biomarker in Cholestatic Infants with Congenital Heart Disease

Sindhu Pandurangi, Michael E. Kim, Nicolas Noriega, Bradley Conant, JangDong Seo, Reena Mourya, Pranavkumar Shivakumar, Anna L. Peters, Andrew Misfeldt, Meghan Chlebowski Children’s Medical Center of Dallas and University of Texas Southwestern Medical Center. Hospital for Sick Children. University of Cincinnati College of Medicine and Cincinnati Children’s Hospital Medical Center. United States Pediatric CardiologyPediatr Cardiol

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The molecular consequences of FOXF1 missense mutations associated with alveolar capillary dysplasia with misalignment of pulmonary veins

G. G. Edel, M. van Kempen, A. Boerema‑de Munck, C. N. Huisman, C. A. P. Naalden, R. W. W. Brouwer, S. Koornneef, W. F. J. van IJcken, R. M. H. Wijnen, R. J. RottierErasmus MC-Sophia. Netherlands Journal of Biomedical ScienceJ Biomed Sci 2024; 31: DOI: 10.1186/s12929-024-01088-5 AbstractBackground: Alveolar capillary dysplasia with misalignment of pulmonary veins (ACD/MPV) is

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A bovine model of hypoxia-induced pulmonary hypertension reveals a gradient of immune and matrisome response with a complement signature found in circulation

Jason Williams, Franklyn N. Iheagwam, Sean P. Maroney, Lauren R. Schmitt, R. Dale Brown, Greta M. Krafsur, Maria G. Frid, Maxwell C. McCabe, Aneta Gandjeva, Kurt J. Williams, James P. Luyendyk, . Anthony J. Saviola, Rubin M. Tuder, Kurt Stenmark, Kirk C. HansenUniversity of Colorado Denver and University of Colorado Anschutz Medical Campus. Michigan State

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Principles of resuscitation for infants with severe bronchopulmonary dysplasia

Summer Elshenawy, Monique R. Radman-Harrison, Philip T. Levy, Satyan Lakshminrushimha, Taylor L. Sawyer, Brenda H. LawChildren’s Healthcare of Atlanta and Emory University School of Medicine. Seattle Children’s Hospital and University of Washington School of Medicine. Boston Children’s Hospital and Harvard Medical School. UC Davis Children’s Hospital, UC Davis Health. University of Alberta Faculty of Medicine

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Actigraphy Study Endpoints to Reduce Sample Size and Facilitate Drug Development for Pediatric Pulmonary Arterial Hypertension

Haihao Sun, Norman Stockbridge, D. Dunbar Ivy, Jennifer Clark, Angela Bates, Stephanie S. Handler, Usha S. Krishnan, MAry P. Mullen, Delphine Yung, Rachel K. Hopper, Nidhy P. Varghese, Catherine M. Avitabile, Jeff Fineman, Eric D. Austin, Grace FreireU.S. Food and Drug Administration. University of Colorado School of Medicine. Stollery Children’s Hospital and University of Alberta.

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Accidental finding of ALCAPA in a child with severe mitral regurgitation: A case study

Budi Rahmat, Radityo Prakoso, Rafles Ph Simbolon, Albert T. Lopolisa, Muhammad Rayhan, Eva M. MarwaliNational Cardiovascular Center Harapan Kita and Universitas Indonesia. Indonesia Asian Cardiovascular Thoracic AnnalsAsian Cardiovasc Thorac Ann 2024; DOI: 10.1177/02184923241295550 AbstractCase report: A six-year-old child who had undergone cardiac surgery five years ago presented to us with severe mitral valve regurgitation. During her current

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Oral sildenafil versus bosentan for treatment of persistent pulmonary hypertension of the newborn: a randomized controlled trial

Aditya Kallimath, Sujata Deshpande, Pari Singh, Reema Garegrat, Satyan Lakshminrusimha, Rajesh Maheshwari, Pradeep SuryawanshiBharati Vidyapeeth (Deemed to be University) Medical College. Imperial College. University of California Davis Children’s Hospital. Westmead Hospital.India, United Kingdom, United States and Australia BioMedical Central PediatricsBMC Pediatr 2024; 24: DOI: 10.1186/s12887-024-05107-0 AbstractBackground: Access to inhaled nitric oxide (iNO) is limited in low resource

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Oxygen saturation targets in neonatal care: A narrative review

Tri C. Nguyen, Rajeshwari Madappa, Heather M. Siefkes, Michelle J. Lim, Kanya Mysore Siddegowda, Satyan LakshminrusimhaKaiser Permanente North California. SIGMA Hospital. University of California Davis Children’s Hospital.United States Early Human DevelopmentEarly Hum Dev 2024; 199:DOI: 10.1016/j.earlhumdev.2024.106134 AbstractOptimal oxygenation requires the delivery of oxygen to meet tissue metabolic demands while minimizing hypoxic pulmonary vasoconstriction and oxygen toxicity.

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