Pediatric Pulmonary Vascular Disease

Incidence of Newborns with Down Syndrome and Factors Associated with Their Length of Hospital Stay in Hospital Pakar Universiti Sains Malaysia

Muhammad Zul Hilmi Muhammad Zain, Ariffin Nasir, Najib Majdi Yaacob, Nor Rosidah IbrahimUniversiti Sains Malaysia. Malaysia Malaysian Journal of Medical SciencesMalays J Med Sci 2025; 32: 203-211DOI: 10.21315/mjms-10-2024-838 AbstractBackground: Down syndrome (DS) is the most common chromosomal disorder worldwide. This study aimed to analyse the incidence of newborns with DS in a tertiary centre in the East […]

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Sotatercept in Children with Pulmonary Hypertension-A Narrative Review

Johanna Schulz, Veronika C. Stark, Lars Harbaum, Rainer Kozlik-Feldmann, Thomas S. Mir, Fridrike Stute, Jakob OlfeUniversity Heart & Vascular Center Hamburg. University Medical Centre Hamburg-Eppendorf Hamburg.Germany ChildrenChildren 2026; 13: DOI: 10.3390/children13040465 AbstractBackground/objectives: Pulmonary arterial hypertension (PAH) is a rare but life-threatening disease that presents particular therapeutic challenges in children. It is characterized by pulmonary vasoconstriction and vascular

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Extracorporeal membrane oxygenation as a bridge to cardiac catheterization in a pediatric patient with pulmonary arteriovenous malformation: A case report and literature review

Mohammed Alzaid, Nada Aljassim, Turki Alshahrani, Abubaker Alkalifa, Anfal Alsalhi, Mohammed AlGhoshimi, Omar AltamimiChildren’s Specialized Hospital, King Fahad Medical City. Saudi Arabia Respiratory Medicine Case ReportsRespir Med Case Rep 2026; DOI: 10.1016/j.rmcr.2026.102417 AbstractIntroduction: Pulmonary arteriovenous malformations (PAVMs) are rare vascular anomalies that can present with profound hypoxemia in children. While transcatheter embolization is the treatment of choice,

Extracorporeal membrane oxygenation as a bridge to cardiac catheterization in a pediatric patient with pulmonary arteriovenous malformation: A case report and literature review Read More »

Efficacy and safety of fenfluramine in Dravet syndrome; A monocentric, observational study focused on initial dose, blood concentration, and reduction of concomitant medications

Akihiro Iguchi, Tokito Yamaguchi, Yu Tsuyusaki, Hideyuki Otani, Satoshi Mizutani, Mitsuhiro Miyashita, Manami Yabe, Katsumi ImaiNHO Shizuoka Institute of Epilepsy and Neurological Disorders and Asahi General Hospital. Japan Epilepsy and BehaviorEpilepsy Behav 2026; DOI: 10.1016/j.yebeh.2026.111070 AbstractObjective: To evaluate the optimal initial dose, efficacy, and adverse events of fenfluramine (FFA) in the treatment of intractable epilepsy in Dravet

Efficacy and safety of fenfluramine in Dravet syndrome; A monocentric, observational study focused on initial dose, blood concentration, and reduction of concomitant medications Read More »

A child with cobalamin C deficiency caused by complex heterozygous variation of c.567dupT and c.80A > G complicated with pulmonary arterial hypertension and hydrocephalus: A case report and literature review

Cui, Xuxia, Zhong, Yajing, Yin, ChongjuanFirst Hospital of Shanxi Medical University.China MedicineMedicine 2026; 105: DOI: 10.1097/MD.0000000000048340 AbstractRationale: Cobalamin C (cblC) deficiency is one of the most common congenital vitamin B12 metabolic abnormalities, and may cause severe neurologic symptoms, gastrointestinal and nephritic symptoms.Patient concerns: A 9-month-old boy presented with a 10-day history of progressive dyspnea and weak cough, accompanied by

A child with cobalamin C deficiency caused by complex heterozygous variation of c.567dupT and c.80A > G complicated with pulmonary arterial hypertension and hydrocephalus: A case report and literature review Read More »

Parental knowledge and awareness of complications of recurrent adenotonsillitis and its surgical management in children in the Jazan region, Saudi Arabia: a cross-sectional study

Abdulelah A. Otaif, Ramzi M. Dighriri, Abdulrahman A. Otaif, Riyadh A. Jahlan, Osama A. Alotayf, Ali Y. Shaikh, Saud N. Alwadani, Raghad M. Alnami, Asma M. SoweediJazan University, Jazan. Armed Forces Hospital.Saudi Arabia Frontiers in PediatricsFront Pediatr 2026; DOI: 10.3389/fped.2026.1761634 AbstractBackground: Recurrent adenotonsillitis is a frequent pediatric condition with complications affecting sleep, growth, hearing, and behavior. Parental

Parental knowledge and awareness of complications of recurrent adenotonsillitis and its surgical management in children in the Jazan region, Saudi Arabia: a cross-sectional study Read More »

Bronchopulmonary Dysplasia: A Contemporary Review for Pediatric Practice

Marie Berg, Silvia Maria del Rocio Delgado-Villalta, Catalina BazacliuUniversity of Florida College of Medicine. United States Pediatrics in ReviewPediatr in Rev 2026; DOI: 10.1542/pir.2024-006701 AbstractBronchopulmonary dysplasia (BPD) remains a significant source of morbidity and mortality among preterm infants, especially those born before 28 weeks gestation. Although the survival of preterm infants has improved, the incidence of

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Plasma Asymmetric Dimethylarginine as a Biomarker of Disease Severity and Therapeutic Response in Neonatal Persistent Pulmonary Hypertension: An Observational Prospective Case-Control Study

Rania M Abdou, Maged A. El Wakeel, Ghada M. El-Kassas, Walaa H. Ali, Hend M. Ahmed, Mohamed Agha, Mohamed Abdel Atti Abdel Fatah, Ramy Saleh Abdelghany, Kareem Salah Eldin Fekry Madbouly, Haidy Badei Mohamad, Iman Shawky Hassan, Mohamed Abdelsalam Mohamed Ahmed, Heba T. Okda, Hatem Attia Mostafa Ismail Ain Shams University. Child Health Department, National

Plasma Asymmetric Dimethylarginine as a Biomarker of Disease Severity and Therapeutic Response in Neonatal Persistent Pulmonary Hypertension: An Observational Prospective Case-Control Study Read More »

Treprostinil Is Associated With Early and Sustained Improvement in Group 3 Pulmonary Hypertension and Right Ventricular Function in Children

Kaushik Parvathaneni, Justin J. Kochanski, Megha D. Tandel, Esther Liu, Alisa Arunamata, Jeffrey A. Feinstein, Rachel K. HopperStanford University School of Medicine and Stanford University.United States Pulmonary CirculationPulm Circ 2026; 16: DOI: 10.1002/pul2.70304 AbstractUse of subcutaneous treprostinil (TRE) in children with pulmonary hypertension (PH) secondary to lung disease (group 3 PH) is not well described. We

Treprostinil Is Associated With Early and Sustained Improvement in Group 3 Pulmonary Hypertension and Right Ventricular Function in Children Read More »

Adapting the REVEAL Lite 2 score to the pediatric population through machine learning: insights from the REHIPED registry for pediatric pulmonary hypertension

Julia Playán-Escribano, Carlos Labrandero de Lera, Leticia Albert de la Torre,  Alejandro Rodríguez-Ogando, Antonio Moreno-Galdó, Inmaculada Guillén Rodríguez, Anna Sabaté-Rotés, Amparo Moya-Bonora, Lina María Caicedo Cuenca, María Jesús del Cerro, on behalf of the REHIPED investigatorsHospital General Universitario Gregorio Marañón. Hospital Universitario del Sureste, Arganda del Rey. Universidad Complutense de Madrid. Hospital Universitario La Paz. Hospital Universitario 12 de Octubre. Hospital General Universitario Gregorio Marañón. Hospital Universitari Vall d’Hebron, Vall d’Hebron Barcelona Hospital Campus,

Adapting the REVEAL Lite 2 score to the pediatric population through machine learning: insights from the REHIPED registry for pediatric pulmonary hypertension Read More »

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