Pediatric Pulmonary Vascular Disease

Treprostinil Use in the NICU

Diana LeeUniversity of Pennsylvania School of Nursing.United States Advances in Neonatal CareAdv Neonat Care 2024; 24: 554-560DOI: 10.1097/ANC.0000000000001218 AbstractBackground: Treprostinil is a prostacyclin analogue that is frequently used in the pediatric and adult population to treat pulmonary hypertension; however, it is not often a drug of choice for patients in the neonatal intensive care unit (NICU).Purpose: To evaluate […]

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The Role of Early Child Nutrition in Pulmonary Hypertension – A Narrative Review

Alina-Costina Luca, Cristina Stoica, Cosmin Diaconescu, Elena T. Tarcă, Solange Tamara Ros, Lăcrămioara Ionela Butnariu, Bogdan Aurelian Stana, Bogdan Gafton, Antoanela Curici, Eduard Vasile Ros, Dana Elena Mîndru“Grigore T. Popa” University of Medicine and Pharmacy. Emergency Hospital for Children “Sfanta Maria”. ”Carol Davila” University of Medicine and Pharmacy.Romania ChildrenChildren 2024; 11: DOI: 10.3390/children11111307 AbstractPulmonary hypertension is

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Clinical Characteristics and Outcomes of SARS-CoV-2 Infection in Neonates with Persistent Pulmonary Hypertension of the Newborn (PPHN): A Systematic Review

Saad Alhumaid, Muneera Alabdulqader, Zainab Al Alawi, Mohammed A. Al Ghamdi, Mohammed A. Alabdulmuhsin, Hassan I. Al Hassar, Hussain Ahmed Alsouaib, Hussain Ali Alhassan, Hassan Al-Helal, Sameer Ahmed Almoraihel, Mohammed Jaber Alomran, Hassan Redha AL-Tarfi, Abbas Radi Al-Makinah, Tariq T. Alghareeb, Mohammad Abdullah Alkhwaitem, Murtadha Alsuliman, Ali N. Bukhamseen, Khulood Khaled Alajmi, Ahmed Salman Al

Clinical Characteristics and Outcomes of SARS-CoV-2 Infection in Neonates with Persistent Pulmonary Hypertension of the Newborn (PPHN): A Systematic Review Read More »

MicroRNA Profiling to Inform Disease Classification, Severity, and Treatment Response in Pediatric Pulmonary Hypertension

Michael A. Smith, Sam Chiacchia, Jason Boehme, Sanjeev A. Datar, Emily Morell, Roberta L. Keller, Amy Romer, Elizabeth Colglazier, Clair Parker, Jasmine Becerra, Jeffrey R. FinemanUniversity of California, San Francisco. Stanford University. Children’s Hospital of Philadelphia.United States American Journal of Physiology Heart and Circulatory PhysiologyAm J Physiol Heart Circ Physiol 2024; DOI: https://doi.org/10.1152/ajpheart.00622.2024 AbstractPediatric pulmonary

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Pulmonary arteriovenous malformation in children

Audrey Y. L. Lim, Felix RatjenHospital for Sick Children and University of Toronto.Canada Pediatric PulmonologyPediatr Pulmonol 2024; DOI: 10.1002/ppul.27354 AbstractPulmonary arteriovenous malformations (PAVMs) are rare abnormalities observed mainly in children with hereditary haemorrhagic telangiectasia (HHT). A majority of patients are asymptomatic at the time of detection. However, complications such as hypoxemia, stroke, cerebral abscess and massive

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Glenn circulation causes early and progressive shunting in a surgical model of pulmonary arteriovenous malformations

Tina C. Wan, Henry Rousseau, Carol Mattern, Madeline Tabor, Matthew R. Hodges, Ramani Ramchandran, Andrew D. SpearmanMedical College of Wisconsin and Children’s Wisconsin.United States Physiological ReportsPhysiol Rep 2024; 12: DOI: 10.14814/phy2.70123 AbstractPulmonary arteriovenous malformations (PAVMs) universally develop in patients with single ventricle congenital heart disease. Single ventricle PAVMs have been recognized for over 50 years but

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Experience of patent ductus arteriosus ligation during extracorporeal membrane oxygenation treatment in newborns with severe respiratory failure due to persistent pulmonary hypertension: a single-center retrospective study

Qi-Liang Zhang, Yi-Nan Liu, Ya-Ting Zeng, Yi-Rong Zheng, Qiang ChenFujian Children’s Hospital, Shanghai Children’s Medical Centerand Fujian Medical University.China Italian Journal of PediatricsItal J Pediatr 2024; 50: DOI: 10.1186/s13052-024-01821-8 AbstractBackground: The aim of this study is to summarize our center’s experience with patent ductus arteriosus (PDA) ligation during extracorporeal membrane oxygenation (ECMO) treatment in newborns with severe

Experience of patent ductus arteriosus ligation during extracorporeal membrane oxygenation treatment in newborns with severe respiratory failure due to persistent pulmonary hypertension: a single-center retrospective study Read More »

Left-Sided Atrioventricular Valve Regurgitation After the Repair of Complete Atrioventricular Septal Defect

Takaya Hoashi, Akinori Hirano, Ryusuke Hosoda, Haruhiro Nagase, Yuji Fuchigami, Yukino Iijima, Takaaki SuzukiSaitama Medical University International Medical Center.Japan Pediatric CardiologyPediatr Cardiol 2024; DOI: 10.1007/s00246-024-03707-2 AbstractThis study aimed to investigate left-sided atrioventricular valve outcome after the repair of complete atrioventricular septal defect from single-institutional retrospective chart review. From 1998 to 2022, 55 patients with complete atrioventricular

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Two-Year Outcomes in Preterm Infants Suffering from Moderate to Severe Bronchopulmonary Dysplasia with or without Associated Pulmonary Hypertension

Irina Branescu, Dragos Ovidiu Alexandru, Simona Vladareanu, Anay KulkarniCarol Davila University of Medicine and Pharmacy. St. George’s University Hospital and St George’s University. University of Medicine and Pharmacy. Royal Brompton Hospital NHS Foundation Trust.Romania and United Kingdom Current Health Sciences JournalCurr Health Sci J 2024; 50: 436-443DOI: 10.12865/CHSJ.50.03.11 AbstractObjectives: To assess the impact of pulmonary hypertension (PH)

Two-Year Outcomes in Preterm Infants Suffering from Moderate to Severe Bronchopulmonary Dysplasia with or without Associated Pulmonary Hypertension Read More »

Population pharmacokinetics of selexipag for dose selection and confirmation in pediatric patients with pulmonary arterial hypertension

Lene Nygaard Axelsen, Anne Kümmel, Juan Jose Perez Ruixo, Alberto RussuActelion Pharmaceuticals and Johnson & Johnson, Allschwil. Janssen-Cilag S.p.A.Switzerland, Spain and Italy Clinical Pharmacology and Therapeutics: Pharmacometrics and Systems PharmacologyCPT Pharmacometrics Syst Pharmacol 2024;DOI: 10.1002/psp4.13231 AbstractSelexipag is an oral selective prostacyclin receptor agonist approved for the treatment of pulmonary arterial hypertension (PAH) in adults. To date,

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