Pediatric Pulmonary Vascular Disease

Pulmonary edema in infants and children

Hugh O’BrodovichHospital for Sick Children and University of Toronto.Canada Current Opinion in PediatricsCurr Opin Pediatr 2005; 7: 381-384DOI: 10.1097/01.mop.0000159780.42572.6c AbstractPurpose of review: To provide an overview of the pathogenesis of pulmonary edema and describe recent discoveries related to the clearance of airspace fluid and potential new therapies for this life-threatening disorder.Recent findings: It is clinically important to determine […]

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The Use of Treprostinil for Bronchopulmonary Dysplasia Associated Pulmonary Hypertension

Stephanie M. Tsoi, Claire Parker, Elizabeth Colglazier, Shannon Cheung, Mariam Taleb, Hythem Nawaytou, Elena Amin, Jeffrey R. Fineman, Roberta L. KellerUniversity of California San Francisco.United States Pediatric PulmonologyPediatr Pulmonol 2026; DOI: 10.1002/ppul.71448 AbstractBackground: Treprostinil for the treatment of bronchopulmonary dysplasia-associated pulmonary hypertension (BPD-PH) has previously been described in small cohort studies, often used later in the course

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Pulmonary artery pressure and cardiac function in children and adolescents after rapid ascent to 3,450 m

Yves Allemann, Thomas Stuber, Stefano F. de Marchi, Emrush Rexhaj, Claudio Sartori, Urs Scherrer, Stefano F. RimoldiInselspital, University Hospital.Switzerland American Journal of Physiology Heart and Circulation PhysiologyAm J Physiol Heart Circ Physiol 2012; 302: H2646-H2653DOI: 10.1152/ajpheart.00053.2012 AbstractHigh-altitude destinations are visited by increasing numbers of children and adolescents. High-altitude hypoxia triggers pulmonary hypertension that in turn may

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High-Altitude Pulmonary Edema in Mountain Community Residents

Christine Ebert-SantosEbert Family Santos.Columbia High Altitude Medicine and BiologyHigh Alt Med Biol 2017; 18: 278-284DOI: 10.1089/ham.2016.0100 AbstractHigh-altitude pulmonary edema (HAPE) affects lowlanders ascending quickly to elevations above 2440 m. Mountain resident children with no travel can sometimes develop HAPE as was observed over 30 years ago (Fasules et al., 1985). This is not well known and

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Reentry High Altitude Pulmonary Edema in the Himalayas

Satosh Baniya, Christopher Holden, Buddha BasnyatMountain Medicine Society of Nepal. Nepal International Clinic and Himalayan Rescue Association. Oxford University Clinical Research Unit. University of Oxford. Nepal and United Kingdom High Altitude Medicine and BiologyHigh Alt Med Biol 2017; 18: 425-427DOI: 10.1089/ham.2017.0088 AbstractReentry high altitude pulmonary edema (HAPE), a subset of HAPE, is a well recognized, life-threatening

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Safety of a novel portable inhaled nitric oxide generator for therapy of persistent pulmonary hypertension in neonates: a case series study

Yao Zhu, Jiongzhi He, Miner Cai, Lijun Wen, Minxu LiDongguan Maternal and Child Health Care Hospital. First Affiliated Hospital of Jinan University.China Translational PediatricsTransl Pediatr 2025; 14: 3305-3317DOI: 10.21037/tp-2025-535 AbstractBackground: Persistent pulmonary hypertension of the newborn (PPHN) is a life-threatening emergency in neonatal intensive care. Traditional treatments such as cylinder-based nitric oxide (NO) delivery systems rely on

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Fibrotic liver injury in biliary atresia: long-term implications

Maria Hukkinen, Mikko P PakarinenNew Children’s Hospital, University of Helsinki and Helsinki University Hospital.Finland World Journal of Pediatric SurgeryWorld J Pediatr Surg 2025; 8: DOI: 10.1136/wjps-2025-001098 AbstractNormalization of serum bilirubin after Kasai portoenterostomy (KPE) is a prerequisite for long-term native liver (NL) survival. Following a successful KPE, fibrotic liver injury progresses variably, although a significant proportion

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Clinical impact of treprostinil in neonates with persistent pulmonary hypertension refractory to inhaled nitric oxide: A retrospective cohort study

Tae Hyeong Kim, Song Ee Youn, Sung-Hoon ChungKyung Hee University College of Medicine and Kyung Hee University Hospital at Gangdong.Republic of Korea MedicineMedicine 2026; 105: DOI: 10.1097/MD.0000000000046984 AbstractPersistent pulmonary hypertension of the newborn (PPHN) has limited options when unresponsive to inhaled nitric oxide (iNO). We evaluated the role of intravenous treprostinil and whether early response classification

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High-altitude pulmonary edema in children

Ralph C. Frates Jr, Gunyon M. Harrison, George A. EdwardsBaylor Collegeof Medicine and the Texas Institute for Rehabilitation and Research.United States American Journal of Diseases of ChildrenAm J Dis Child 1977; 131: 687-689DOI: 10.1001/archpedi.1977.02120190081018 AbstractA 15-year-old boy with recurrent high-altitude pulmonary edema had previously been mistakenly treated for asthma and pneumonia. Clinical manifestations of this disorder,

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High-altitude pulmonary edema in the children and young adults of Leadville, Colorado

Charles H. Scoggin, Thomas M. Hyers, John T. Reeves, Robert F. GroverUniversity of Colorado Medical Center. United States New England Journal of MedicineN Engl J Med 1977; 297: 1269-1272DOI: 10.1056/NEJM197712082972309 AbstractAbstract Not Available CategoryHigh Altitude Pulmonary Edema Age Focus: Pediatric Pulmonary Vascular Disease Fresh or Filed Publication: Filed (PHiled). Greater than 1-2 years since publication Article

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