Pediatric Pulmonary Vascular Disease

Isolated prenatal foramen ovale closure or restriction presenting after birth: a distinct, under-recognized clinical condition

Tomaž Podnar, Ralf Geiger, Ira Winkler, Elke Griesmaier, Susanne Sprung, Ursula Kiechl-KohlendorferMedical University of Innsbruck. Tirol Kliniken.Austria Frontiers in PediatricsFront Pediatr 2026; 14: DOI: 10.3389/fped.2026.1753196 AbstractBackground: The foramen ovale (FO) plays a central role in fetal circulation. Prenatal FO closure or restriction is well-characterized in fetuses and in neonates with congenital heart defects, but is rarely described […]

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Alveolar Capillary Dysplasia With Misaligned Pulmonary Veins (ACDMPV): Description of Two Cases and Literature Review

Eleanora Guasti, Giacomo Tardini, Silvia Buratti, Chiara Campone, Erika Alboreto, Martino Cheli, Francesca Faravelli, Daniela Pirlo, Andrea MoscatelliUniversity of Genoa. IRCCS Istituto Giannina Gaslini. Italy Pediatric PulmonologyPediatr Pulmonol 2026; 61: DOI: 10.1002/ppul.71704 AbstractIntroduction: Alveolar capillary dysplasia with misaligned pulmonary veins (ACDMPV) is one of the major causes of neonatal interstitial lung disease, causing persistent pulmonary hypertension (PH)

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Vein of Galen Malformation Masquerading as Neonatal Respiratory Distress

Hadi Fakih, Hussein A. Hussein, Fatima FakihSheikh Ragheb Harb University Hospital. Lebanese University. Lebanon Cureus Cureus 2026; 18: DOI: 10.7759/cureus.109082 AbstractVein of Galen malformation (VoGM) is a rare congenital vascular anomaly. It represents a well-recognized extracardiac cause of high-output cardiac failure in the neonatal period. We report a case of a 3.5-month-old boy who presented for

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Efficacy and safety of bosentan-related therapy in neonates with persistent pulmonary hypertension of the newborn: a systematic review and meta-analysis

Guanghong Li, Xiaoqun Du, Weibin Luo, Junhua Wei, Huiyi HuangHuadu District People’s Hospital of Guangzhou.China Frontiers in PediatricsFront Pediatr 2026; 14: DOI: 10.3389/fped.2026.1836276 AbstractObjective: To evaluate the efficacy and safety of bosentan-related therapy in neonates with persistent pulmonary hypertension of the newborn (PPHN).Methods: PubMed, Web of Science, the Cochrane Library, and ClinicalTrials.gov were searched from inception to March

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Clinical and echocardiographic characteristics of patients presenting with pulmonary hypertension due to congenital heart disease

M. M. F. Henema, F. E. Smit, S. C. Brown, L. BotesDr. George Mukhari Academic Hospital. Central University of Technology. University of the Free State. South Africa Cardiovascular Journal of AfricaCardiovasc J Afr 2026; 37: 53-61DOI: 10.5830/CVJA-2025-094 AbstractBackground: This study aimed to assess patients’ clinical and echocardiographic features in pulmonary hypertension (PH) due to congenital heart disease

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Recurrent Seizure-Like Events in a Toddler With BMPR2-Related Pulmonary Arterial Hypertension

Nur Sena Cagatay, Neha Ahluwalia, Aimee LuatChildren’s Hospital of Michigan.United States Ochsner JournalOchsner J 2026; 26: 179-182DOI: 10.31486/toj.25.0109 AbstractBackground: Seizure-like episodes are common in children, but many spells are not true epileptic seizures. Cardiac or pulmonary conditions such as pulmonary arterial hypertension can be the cause of the seizure-like episodes, particularly when the events persist despite administration

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Autologous stem cell transplantation (ASCT) for Refractory juvenile-onset systemic sclerosis (JSSc)

Kathryn S. Torok, Paulina Horvei, Jonathan Li, Franziska Rosser, Jessie L. Alexander, Kirsten Rose-felker, Vibha Sood, Adam Olson, Nicole Hogue, Vickie Vandergrift, Heather Stanczak, Maura Miglioretti, Lauren Farver, Wendy Koster, Devin Mcguire, Haley Havrilla, Shawna McIntyre, Robyn T. Domsic, Robert A. Lafyatis, Paul SzabolcsUniversity of Pittsburgh Medical Center (UPMC) and Children’s Hospital of Pittsburgh. Stanford

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Pulmonary Endarterectomy in Pediatric Patients: Institutional Experience

Çağatay Çetinkaya, Nezih Onur Ermerak, Ela Erdem, Figen Akalın, Koray Ak, Eylem Tuncer, Altuğ Sağır, Bedrettin Yildizeli BedrettinUskudar University. Marmara University. University of Health Sciences.Turkey Thoracic and Cardiovascular SurgeonThorac Cardiovasc Surg 2026; DOI: 10.1055/a-2875-1852 AbstractBackground: Chronic thromboembolic pulmonary hypertension (CTEPH) is rare in children and published experience with pulmonary endarterectomy (PEA) is limited.Methods: We retrospectively reviewed six patients

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Pediatric Pulmonary Infarction and Infarction-Like Pulmonary Injury: An Etiology-Oriented Narrative Review

Shuxuan Li, Yanran Zhang, Xiangxiang Tian, Wanqing Zhao, Yongsheng XuTianjin Medical University and Tianjin Children’s Hospital (Children’s Hospital of Tianjin University).China Seminars in Thrombosis and HemostasisSemin Thromb Hemost 2026; DOI: 10.1055/a-2889-7005 Abstract Pulmonary infarction (PI) has traditionally been regarded as a complication of pulmonary embolism (PE). However, increasing evidence suggests that pediatric PI represents a heterogeneous

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Extracorporeal Membrane Oxygenation in Pediatric Pulmonary Hypertension: A Single-Center Cohort to Inform Decision-Making

Taylor M. Smith, Kathryn Restaino, Stuart Lipsitz, Jai Krishan Khurana, Mary P. Mullin, John N. Kheir, Katie M. MoynihanBoston Children’s Hospital, Brigham and Women’s Hospital and Harvard Medical School. United States American Society of Artificial Internal Organs JournalASAIO J 2026; DOI: 10.1097/MAT.0000000000002766 AbstractLimited data describe children with pulmonary hypertension (PH) supported on extracorporeal membrane oxygenation (ECMO).

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