Pediatric Pulmonary Vascular Disease

The First 1000 Days: Maternal Nutrient Intake-A Window of Opportunity for Pulmonary Hypertension-A Narrative Review

Alina-Costina Luca, Solange Tamara Rosu, Cosmin Diaconescu, Dana Elena Mîndru, Cristina Gavrilovici, Adriana Vizireanu, Viorel Tarcă, Eduard Vasile Rosu, Elena TarcăGrigore T. Popa University of Medicine and Pharmacy. Apollonia University. Romania NutrientsNutrients 2026; 18: DOI: 10.3390/nu18030424 AbstractThe first 1000 days of life, starting from conception to a child’s second birthday, constitute a pivotal period for fetal […]

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Cardiac Magnetic Resonance Findings and Their Association with Clinical Outcomes in Pediatric Pulmonary Arterial Hypertension: An Exploratory Study

Meryem Beyazal, Merter Keceli, Oguzhan Dogan, Ibrahim EceChildren Hospital and Ankara Bilkent City Hospital.Turkey Journal of Clinical MedicineJ Clin Med 2026; 15: DOI: 10.3390/jcm15031107 AbstractBackground: Cardiac magnetic resonance [CMR] is a non-invasive tool to assess ventricular function in pediatric pulmonary arterial hypertension [PAH]. However, CMR parameters in children remain underexplored. Methods: Thirty-six children with PAH were prospectively

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Development of a Robust, Rapid and Reliable Tandem Mass Spectrometry Method for the Measurement of Sildenafil, Bosentan and their Major Metabolites

Mohammad Ahmad Bik, Duygu Eryavuz, Onmaz, Karem Mazin Kamil Gharab, Fadime Karaman, Sedat Abusoglu, Abdullah Sivrikaya, Ali UnluSelcuk University. Mustansiriyah University.Turkey and Iraq Indian Journal of Clinical BiochemistryIndian J Clin Biochem 2026; 41: 113-119DOI: 10.1007/s12291-024-01215-x AbstractPulmonary arterial hypertension (PAH) is a lethal, progressive disease with a complex pathogenesis. Bosentan, a dual endothelin receptor antagonist, and sildenafil,

Development of a Robust, Rapid and Reliable Tandem Mass Spectrometry Method for the Measurement of Sildenafil, Bosentan and their Major Metabolites Read More »

Beyond the Echocardiogram: Cardiac Catheterization in Infants With Bronchopulmonary Dysplasia Associated Pulmonary Hypertension

Samuel J. Gentle, Audrey HebertYale School of Medicine. Centre Hospitalier Universitaire de Quebec.United States and Canada Journal of PediatricsJ Pediatr 2026; DOI: 10.1016/j.jpeds.2026.115026 AbstractAbstract Not Available CategoryClass III. Pulmonary Hypertension Associated with Lung DiseaseDiagnostic Testing for Pulmonary Vascular Disease. Non-invasive TestingDiagnostic Testing for Pulmonary Vascular Disease. Invasive Testing Age Focus: Pediatric Pulmonary Vascular Disease Fresh or

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Impact of Hernia Sac in Congenital Diaphragmatic Hernia: Associations with Morbidity and Mortality

Krysta M Sutyak 1, Kylie I Holden 2, Charles Green 3, Matthew T Harting 2, KuoJen Tsao 4, Kouji Nagata 5, Richard Keijzer 6, Marietta Jank 6, Tim Jancelewicz 7, Joseph T Church 8, Pamela A Lally 2, Kevin P Lally 4; For, The Congenital Diaphragmatic Hernia Study Group McGovern Medical School and University of Texas Health Science Center at Houston and Children’s Memorial Hermann Hospital. Kyushu University. University of Manitoba. University of Tennessee Health Science Center. University of

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Endomyocardial calcification with pulmonary and systemic hypertension in a term neonate with multisystem inflammatory syndrome of newborn (MIS-N)

Swasthi Kabi Satpathy. Choudri Muzafar Paswal, Neeraj Gupta, Jai Prakash Soni, Sushil Kumar ChoudharyAll India Institute of Medical Sciences Jodhpur. Dr Sampurnanand Medical College.India British Medical Journal Case ReportsBMJ Case Rep 2026; 19:DOI: 10.1136/bcr-2025-270053 AbstractMultisystem inflammatory syndrome in neonates (MIS-N) is a rare condition linked to perinatal exposure to SARS-CoV-2. We report a case of a

Endomyocardial calcification with pulmonary and systemic hypertension in a term neonate with multisystem inflammatory syndrome of newborn (MIS-N) Read More »

Liver herniation in congenital diaphragmatic hernia is associated with delayed resolution of pulmonary hypertension

Uthaya Kumaran Kanagaraj, Mimi T.Y. Kuan, Michael Castaldo, Erik Skarsgard, Joseph Y. TingUniversity of British Columbia. University of Alberta.Canada Pediatrics and NeonatologyPediatr Neonatol 2026; DOI: 10.1016/j.pedneo.2025.11.011 AbstractBackground: Severe and persistent pulmonary hypertension (PH) predicts mortality and short-term pulmonary morbidity in infants with congenital diaphragmatic hernia (CDH). Intrathoracic liver herniation (liver-up) is a predictor of survival and increased

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Scimitar syndrome presenting in infancy

Charles B. Huddleston, Vernat Exil, Charles E. Canter, Eric N. MendeloffWashington University School of Medicine and St. Louis Children’s Hospital.United States Annals of Thoracic SurgeryAnn Thorac Surg 1999; 67: 154-159DOI: 10.1016/s0003-4975(98)01227-2 AbstractBackground: Scimitar syndrome has a variable presentation based on the age at which the diagnosis is made. In general, infants presenting in heart failure have a

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A Novel Rat Model for Group 2 Pulmonary Hypertension by Total Pulmonary Vein Banding: Multi-Omics Insights into Pathophysiological Mechanisms

Jin Shentu, Wenxuan Dai, Chang Chen, Jiawei Huang, Lijun Chen, Yi Yan, Han Zhang, Zhongqun Zhu, Guocheng Shi, Huiwen ChenShanghai Children’s Medical Center and Shanghai Jiao Tong University School of Medicine. China Journal of Thoracic and Cardiovascular SurgeryJ Thorac Cardiovasc Surg 2026; DOI: 10.1016/j.jtcvs.2026.01.017 AbstractObjectives: Group 2 pulmonary hypertension (PH) remains a highly morbid disease, yet no

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Expanding the phenotypic spectrum of MECOM-associated syndrome: rare variants are associated with syndromic pulmonary arterial hypertension

Carrie L. Welch , Meriel McEntagart, Shahin Moledina, Cara Morgan, Emilia Swietlik, Chao Hou, Lu Qiao, Emily Callejo, Savanna Craib, Damian Smedley, Emilia K. Bijlsma, Patrice Bouvagnet, Nahir Cortes-­Santiago, Tamir Dagan, Jacqueline Eason, Frances Flinter, Aakash Joshi, Jeremie Mortreux, Fadel E. Ruiz, Deborah Shears, Celia Azevedo Soares, Nidhy P. Varghese, Wendy K ChungBoston Children’s Hospital,

Expanding the phenotypic spectrum of MECOM-associated syndrome: rare variants are associated with syndromic pulmonary arterial hypertension Read More »

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