Pediatric Pulmonary Vascular Disease

A hemodynamic-driven approach to chronic pulmonary hypertension in congenital diaphragmatic hernia

Carly E. Byrd, John T. Wren, Suneetha Desiraju, Patrick J. McNamaraJohns Hopkins University School of Medicine. University of Iowa Hospitals and Clinics.United States Journal of PerinatologyJ Perinatol 2026; DOI: 10.1038/s41372-026-02582-4 AbstractDespite ample research in acute pulmonary hypertension in neonates with congenital diaphragmatic hernia (CDH) leading to improved survival, there is a paucity of literature on the […]

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Individualised interventional strategies and clinical outcomes in paediatric patients with pulmonary arterial hypertension

Emine Gulsah Torun, Oguzhan Dogan, Denizhan Bagrul, Ibrahim EceMinistry of Health Ankara Bilkent City Hospital.Turkey Cardiology in the YoungCardiol Young 2026; DOI: 10.1017/S104795112611141X AbstractObjective: This study evaluated the safety and efficacy of individualised interventional strategies in paediatric pulmonary arterial hypertension, focusing on the outcomes of atrial septostomy, reverse Potts shunt, and partial ASD closure in patients unresponsive

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Initial Hemodynamic Phenotypes and Clinical Trajectory in Congenital Diaphragmatic Hernia: A Pilot Study

John T. Wren Jr., Rachael M. Hyland, Patrick J. McNamaraUniversity of Iowa Healthcare.United States Journal of PediatricsJ Pediatr 2026; DOI: 10.1016/j.jpeds.2026.115044 AbstractObjectives: To define clinically the initial (<24 hour) hemodynamic phenotypes (no/mild pulmonary hypertension [PH], pre-capillary PH, and post-capillary PH) in neonates with congenital diaphragmatic hernia (CDH) by echocardiography, and to assess their relationship with clinical outcomes.Study

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A Rare Case of Reversible Pulmonary Hypertension Phenotype in a Child with Scurvy: Aetiologies Insights

Mattia Pasquinucci, Luisa Bonsembiante, Sofia Mezzalira, Martina Locallo, Davide MeneghessoAULSS 7 Pedemontana-San Bassiano Hospital. IRCCS Istituto Giannina Gaslini. University of Padua.Italy ReportsReports 2026; DOI: 10.3390/reports9010044 AbstractBackground and Clinical Significance: Scurvy, caused by chronic vitamin C deficiency, is re-emerging in Western countries, particularly among pediatric patients with highly selective diets. While its musculoskeletal and mucocutaneous manifestations are well-known,

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Current State of RV Multimodality Imaging in Pediatric Pulmonary Hypertension: Current Evidence, Knowledge Gaps, and Future Research Directions

Kimberley G. Miles, Dan M. Dorobantu, Johannes Menno Douwes, Benjamin S. Frank, Pei-Ni Jone, Vivek Muthurangu, D. Dunbar Ivy, Hythem Nawaytou, Mark K. FriedbergCincinnati Children’s Hospital and University of Cincinnati College of Medicine. Bristol Royal Hospital for Children and Heart Institute. Beatrix Children’s Hospital, University Medical Center Groningen and University of Groningen. University of Colorado Denver Anschutz

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Peri and Neonatal Risk Factors and Structural Lung Abnormalities Predict Hypoxic Challenge Test Failure in Infants With Severe Bronchopulmonary Dysplasia

Kishan D. Tsang, Daan Caudri, Citta Zaat, Gerdien A. Tramper‐Stranders, Isme M. de Kleer, Pierluigi Ciet, Irwin K. M. Reiss, Liesbeth Duijts, Mariëlle W. PijnenburgErasmus Medical Centre, Sophia Children’s Hospital and University Medical Center. Franciscus Gasthuis & Vlietland. University of Cagliari. University Children’s Hospital, University Medical Center Hamburg Eppendorf. Netherlands, Italy, Germany Pediatric PulmonologyPediatr Pulmonol

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Predicting pulmonary hypertension in infants with bronchopulmonary dysplasia

Henry P. Foote, Minghui Sun, Benjamin Alan Goldstein, Kevin D. Hill, Rachel G. Greenberg, Samuel J. Gentle, Kanecia O. Zimmerman, Rishikesan Kameleswaran, Veeral N. Tolia, Matthew M. Laughon, Wesley Jackson, Christoph P. HornikDuke University Medical Center and Duke University. Yale University School of Medicine. Baylor University Medical Center. University of North Carolina. United States Journal

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Results of a pulmonary hypertension screening program for premature infants with bronchopulmonary dysplasia

Ramya Ramachandra, Alisa Arunamata, Amanda Moy, Michael C. Tracy, Yinyao Ji, Derek Boothroyd, Rachel K. HopperStanford University School of Medicine and Lucile Packard Children’s Hospital.United States Journal of PerinatologyJ Perinatol 2026; DOI: 10.1038/s41372-026-02580-6 AbstractObjective: Premature infants with bronchopulmonary dysplasia (BPD) are at risk for pulmonary hypertension (PH). We sought to evaluate outcomes of a PH screening protocol.Study

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Jinlong Liu, Xiafeng Yu, Jiwen Xiong, Yi Yan, Yanjun Sun, Yumin Zhong, Hao ZhangShanghai Children’s Medical Center and Shanghai Jiao Tong University School of Medicine.China Frontiers in Bioengineering and BiotechnologyFront Bioeng Biotechnol 2026; 13: DOI: 10.3389/fbioe.2025.1697468 AbstractObjectives: Reverse Potts shunt is a promising yet high-risk therapy for pediatric pulmonary arterial hypertension. Postoperative hemodynamics is critically influenced by

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A Large Animal Model of Heritable Pulmonary Arterial Hypertension Using Gene-edited BMPR2 Sheep

Sanjeev A. Datar, Nicholas Werry, Austin R. Brown, Devon S. Fitzpatrick, Oluwafemi Falade, Josephine F. Trott, Rachel Hutchings, Elena K. Amin, Jessica M. Morgan, Hythem Nawaytou, Gail H. Deutsch, Eric G. Johnson, Omar A. Gonzales Viera, Thomas F. Bishop, Tara Urbano, Bret R. McNabb, Eric D. Austin, Jeffery R. Fineman, and Alison L. Van EenennaamUniversity

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