Pediatric Pulmonary Vascular Disease

Urinary leukotriene E4 in pediatric pulmonary arterial hypertension: a pilot case control study

Hamdy El-Sayed, Hala Elmarsafawy, Basma Shouman, Mostafa Mansour, Amal OsmanMansoura University.Egypt Archive de PédiatrieArch Pediatr 2025; DOI: 10.1016/j.arcped.2025.08.004 AbstractBackground: Pediatric pulmonary arterial hypertension (PAH) is a potentially fatal disease. New targeted therapies based on the underlying pathogenesis are still needed.Objective: This study aims to evaluate the role of leukotriene E4, an inflammatory mediator, in developing pediatric pulmonary arterial […]

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Persistent Low-Output Neonatal Chylothorax: How Long Are We Justified to Wait for Pleurodesis in Partial Responders?

G. Rollo, A. Zarfati, G. Burini, L. Valfre, C. Iacusso, I. Capolupo, B. D. Iacobelli, P. Bagolan, A. Conforti, F. FusaroBambino Gesù Children’s Hospital IRCCS. Italy Pediatric PulmonologyPediatr Pulmonol 2025; 60: DOI: 10.1002/ppul.71311 AbstractAims: The aim of our study was to review our experience regarding the management of neonatal chylothorax, with particular focus on outcomes of partial

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Antepartum Thoracocentesis: A Case Report on Congenital Chylothorax

Maria Almeida, Marta Campos, Celia Soares, Cristina Godinho, Maria BritoUnidade Local de Saúde de Trás-os-Montes e Alto.Portugal CureusCureus 2025; 17: DOI: 10.7759/cureus.90275 AbstractCongenital chylothorax remains a poorly understood condition, and the optimal approach to its management continues to evolve. Rapid progression of pleural effusion with mediastinal shift and/or development of hydrops fetalis are key indications for

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Molecular targeted treatment in infants with central conducting lymphatic anomalies

Vera C. van den Brink, Lotte E. R. Kleimeier, Erika K. S. M. Leenders, Willemijn M. Klein, Willem P. de Boode, Joris Fuijkschot, Sabine L. A. G. VranckenAmalia Children’s Hospital, Radboud University Medical Center. Netherlands European Journal of PediatricsEur J Pediatr 2025; 184: DOI: 10.1007/s00431-025-06376-2 AbstractCentral conducting lymphatic anomaly (CCLA) is a rare and potentially life-threatening

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Incidence and risk factors for the development of pulmonary arteriovenous malformations after stage 2 palliation

Lea Behrend, Thibault Schaeffer, Muneaki Matsubara, Jonas Palm, Teresa Lemmen, Nicole Piber, Paul Philipp Heinisch, Stanimir Georgiev, Alfred Hager, Peter Ewert, Jürgen Horer, Masamichi OnoUniversity Hospital of Technische Universität München, University Hospital of Munich and Ludwig-Maximilians-Universität.Germany International Journal of Cardiology Congenital Heart DiseaseInt J Cardiol Congenit Heart Dis 2025; DOI: 10.1016/j.ijcchd.2025.100611 AbstractObjective: This study evaluated the current

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Vardenafil vs. Sildenafil for the Treatment of Persistent Pulmonary Hypertension in Newborns

Sania El-HindiChildren’s Hospital.Syria Indian Journal of PediatricsIndian L Pediatr 2025; DOI: 10.1007/s12098-025-05787-1 AbstractAbstract Not Available CategoryClass I. Persistent Pulmonary Hypertension of the NewbornMedical Therapy. Efficacy or Lack of Efficacy Age Focus: Pediatric Pulmonary Vascular Disease Fresh or Filed Publication: Fresh (PHresh). Less than 1-2 years since publication Article Access Free PDF File or Full Text Article

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Clinical characteristics and prognosis of exchange transfusion in infants with severe pertussis

Pingping Liu, Zhenghui Xiao, Jiaotian Huang, Yanying Chen, Juan LiuAffiliated Children’s Hospital of Xiangya School of Medicine and Central South University. China BioMedical Central PediatricsBMC Pediatr 2025; 25: DOI: 10.1186/s12887-025-06132-3 AbstractBackground: To explore the efficacy and clinical significance of exchange transfusion (ET) therapy in infants with severe pertussis, and provide a basis for the diagnosis and treatment

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Scurvy, a not obsolete disorder: Clinical report in eight young children and literature review

Alessandra Di Nora, Maria Carla Finocchiaro, Francesco Pizzo, Trobia Gian Luca, Maria Elena Cucuzza, Antonella Di Stefano, Serena Spampinato, Silvia Marino, Martino Ruggieri, Piero PavoneUniversity of Catania. Cannizzaro Emergency Hospital. ARNAS Garibaldi Hospital.Italy Open MedicineOpen Med 2025; DOI: 10.1515/med-2024-1086 AbstractBackground: Vitamin C is a key to many important functions. It stimulates the immune system by protecting humans

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Neonatal early-onset sepsis caused by Streptococcus Gallolyticus subsp. Pasteurianus with severe pulmonary hypertension and leukemoid reaction: a case report

Xuelian Wang, Ling Wang, Yuan Yuan, Xiaopeng Zhao, Huayan ZhangGuangzhou Women and Children’s Medical Center and Guangzhou Medical University. Children’s Hospital of Philadelphia.China and United States BioMedical Central PediatricsBMC Pediatr 2025; 25: DOI: 10.1186/s12887-025-06026-4 AbstractBackground: Streptococcus gallolyticus subsp. pasteurianus (SGSP) is an uncommon cause of neonatal early-onset sepsis (EOS). We present a case of neonatal EOS attributed

Neonatal early-onset sepsis caused by Streptococcus Gallolyticus subsp. Pasteurianus with severe pulmonary hypertension and leukemoid reaction: a case report Read More »

Neonatal pulmonary hypertension in the NICU: a 10-year single-center experience

Oguzhan Ay, Sezgin Gunes, Erkan Erfidan, Ayse SimsekIzmir Democracy University and Buca Seyfi Demirsoy Teaching and Research Hospital. Izmir City Hospital. Istanbul Aydin University and VM Medical Park Florya Hospital Istanbul. Turkey BioMedical Central PediatricsBMC Pediatr 2025; 25: DOI: 10.1186/s12887-025-05928-7 AbstractBackround Neonatal pulmonary hypertension (PHT) is a significant cause of morbidity and mortality in newborns. Early

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