Pediatric Pulmonary Vascular Disease

Screening for pulmonary hypertension in preterm infants with bronchopulmonary dysplasia: when, how often and does it matter?

Samuel J. Gentle, Waldemar A. Carlo, Namasivayam AmbalavananUniversity of Alabama at Birmingham. Yale School of Medicine.United States Archives of Disease in Childhood Fetal and Neonatal EditionArch Dis Child Fetal Neonatal Ed 2025; DOI: 10.1136/archdischild-2024-328405 AbstractObjective: Bronchopulmonary dysplasia (BPD) associated pulmonary hypertension (BPD-PH) is the most severe endotype of BPD; there is insufficient evidence to support the optimal […]

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How Is Pulmonary Hypertension Characterised and Treated in Children With Trisomy 21? Observations From the TOPP Registry (Tracking Outcomes and Practice in Pediatric Pulmonary Hypertension)

Tilman Humpl, Rolf M. F. Berger, Damien Bonnet, Maurice Beghetti, Dunbar Ivy, for the TOPP InvestigatorsDistrict Hospital of Loerrach Germany. Beatrix Children’s Hospital. Hôpital Necker Enfants Malades. Children’s University Hospital. Childrens Hospital Colorado and University of Colorado School of Medicine.Germany, Netherlands, France, Switzterland and United States Pulmonary CirculationPulm Circ 2025; 15: DOI: 10.1002/pul2.70146 AbstractPulmonary hypertension is

How Is Pulmonary Hypertension Characterised and Treated in Children With Trisomy 21? Observations From the TOPP Registry (Tracking Outcomes and Practice in Pediatric Pulmonary Hypertension) Read More »

Pulmonary Vascular Compromise Is Associated With Survival in Pediatric Pulmonary Hypertension: A New Computational Model

Maria Niccum, Catherine M. Avitabile, Dana Albizem, Heather Meluskey, Christopher Penney, Brian D. Hanna, Michael L. O’Byrne, Zoheir Bshouty, David B. FrankPerelman School of Medicine at the University of Pennsylvania and Children’s Hospital of Philadelphia. University of Manitoba.United States and Canada Pulmonary CirculationPulm Circ 2025; 15: DOI: 10.1002/pul2.70156 AbstractPediatric pulmonary arterial hypertension (PAH) has a long

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Surviving trisomy 18: A case report of a 5-year-old girl

Mohamad A. Banat, Ramzi Mujahed, Sama S. Yaseen, Nada A. Makhalfeh, Shahed O. Rajabi, Baraa Abu Aisheh, Rama N. BasheerPalestine Polytechnic University. Princess Alia Governmental Hospital.Palestine MedicineMedicine 2025; 104: DOI: 10.1097/MD.0000000000044225 AbstractRationale: Trisomy 18, often known as Edwards syndrome. It is a common chromosomal disorder characterized by the presence of an extra chromosome 18. Unfortunately, survival past

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Successful Treatment of Severe Hepatopulmonary Syndrome as a Rare Complication of Zellweger Spectrum Disorder

Riya Mary Tharakan, Sanjay Rajwal, Bernd C. SchwahnSt Mary’s Hospital Manchester University NHS Foundation Trust. Leeds Children’s Hospital. Medicine and Health University of Manchester. United Kingdom Journal of Inherited Metabolic Disorders ReportsJIMD Rep 2025; DOI: 10.1002/jmd2.70026 AbstractWe report the case of an 11-year-old girl who developed hepatopulmonary syndrome (HPS) as a rare complication of Zellweger spectrum

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Premature monozygotic twins with congenital diaphragmatic hernia: a case report

Muhammet Zahit Koyuncu, Ayşegül Aşkın, Hüseyin Altunhan, Nuriye Emiroğlu, Canan KocaoğluNecmettin Erbakan University. Turkey Sudanese Journal of PaediatricsSudan J Paediatr 2025; 25: 66-70DOI: 10.24911/SJP.106-1746615665 AbstractCongenital diaphragmatic hernia (CDH) is a severe developmental anomaly with variable clinical outcomes, influenced by factors such as liver herniation, pulmonary hypertension and associated anomalies. While familial clustering of CDH has been

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Outcomes for Congenital Diaphragmatic Hernia in Three Decades: A Report From a UK Surgical Centre

Wan Teng Lee, Paul D. LostyUniversity of Liverpool. Alder Hey Children’s Hospital Liverpool. Ramathibodi Hospital and Mahidol University.United Kingdom and Thailand Acta PaediatricaActa Paediatr 2025; DOI: 10.1111/apa.70295 AbstractAims: Congenital diaphragmatic hernia (CDH) is associated with lung hypoplasia, pulmonary hypertension and high mortality. Three decades experience from a UK centre is reported.Methods: Medical records of CDH newborns between February

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Nebulized nitroglycerin as an adjuvant drug in management of persistent pulmonary hypertension of newborns: a randomized controlled trial

Marwa Mohammed Farag, Hesham Abd El‑Rahim Ghazal, Aly Mohamed Abdel‑Mohsen, Moataz Ahmed RezkAlexandria University Hospital, Alexandria. Egypt European Journal of PediatricsEur J Pediatr 2025; 184: DOI: 10.1007/s00431-025-06381-5 AbstractThe objective was to evaluate the effect of nebulized nitroglycerin (NNG) in neonates with persistent pulmonary hypertension (PPHN). The study focused on assessing changes in echocardiographic and clinical parameters

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Arterial Tortuosity Syndrome: A Longitudinal Assessment of Cardiovascular Features and Interventions From the Collaborative for Longitudinal Aortic Research in the Young (CLARITY)

Bita Salamat, Sara B. Stephens, Jolie J. Britt, Taylor Beecroft-Dawson, Andrea Taylor, Laura Muiño Mosquera, Bert Callewaert, Aude Beyens, Alexandra Channing, Michael P. Dilorenzo, Justin Weigand, Benjamin Jacob, Eudice Fontenot, Shaine A. MorrisTexas Children’s Hospital and Baylor College of Medicine. University of Texas Health Science Center. A Twist of Fate. Ghent University Hospital and Ghent

Arterial Tortuosity Syndrome: A Longitudinal Assessment of Cardiovascular Features and Interventions From the Collaborative for Longitudinal Aortic Research in the Young (CLARITY) Read More »

Global Burden of Pediatric Pulmonary Arterial Hypertension, 1990-2021: A Systematic Analysis from the Global Burden of Disease Study 2021

Taixiang Liu, Xiaoliang Liu, Chenhong Wang, Jinxin Zheng, Liping Shi, Zheng ChenChildren’s Hospital, Zhejiang University School of Medicine. West China Second University Hospital, Sichuan University. Shanghai Jiao Tong University School of Medicine. China Pediatric CardiologyPediatr Cardiol 2025; DOI: 10.1007/s00246-025-04009-x AbstractPediatric pulmonary arterial hypertension (PAH) remains a critical global health threat characterized by disparities in burden driven

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