Pediatric Pulmonary Vascular Disease

Causes and risk factors for death in infants with congenital chylothorax

Yuichi Kubo, Satoshi Ibara, Takuya Tokuhisa, Masaya Kibe, Kazuyoshi Sueyoshi, Masato Kamitomo, Motoi KatoShonan Fujisawa Tokushukai Hospital. Kagoshima City Hospital. Imakiire General Hospital. Kagoshima University Hospital.Japan Frontiers in PediatricsFront Pediatr 2025; 13: DOI: 10.3389/fped.2025.1699515 AbstractAim: To identify mortality risk factors in infants with congenital chylothorax (CC) and analyze the causes of death, including pathological examination.Methods: For this single-center […]

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Early screening for respiratory and cardiac complications in pediatric mucopolysaccharidosis IVA: Insights from a case

Haiyan Shu, Xiaohong Shang, Yan Sun, Guimei Li, Chen Chen, Jianmei YangLicheng District Traditional Chinese Medicine Hospital. Shandong Provincial Hospital Affiliated to Shandong First Medical University. University of Queensland. China and Australia Intractable and Rare Diseases ResearchIntractable Rare Dis Res 2025; 14: 303-305DOI: 10.5582/irdr.2025.01053 AbstractMucopolysaccharidosis type IVA (MPS IVA) is a rare genetic disorder characterized by

Early screening for respiratory and cardiac complications in pediatric mucopolysaccharidosis IVA: Insights from a case Read More »

Inactivation of AXL in Cardiac Fibroblasts Alleviates Right Ventricular Remodeling in Pulmonary Hypertension

Li-Wei Wu, Min Chen, Chen-Yu Jiang, Dai-Ji Jiang, Xu Zhang, Xiao-He Xu, Yi-Wei Liu, Bei Feng, Lin-Cai Ye, Yang-Yang He, Xu Huang, Yi-Chi Zhang, Xing-Liang Zhou, Yi Shen, Tian-Yu Liu, Li-Jun Fu, Yi Yan, Hao ZhangShanghai Children’s Medical Center, National Children’s Medical Center and Shanghai Jiao Tong University School of Medicine. Second Affiliated Hospital and

Inactivation of AXL in Cardiac Fibroblasts Alleviates Right Ventricular Remodeling in Pulmonary Hypertension Read More »

Cardiovascular Manifestations and Interventions in Children Living in a Histoplasmosis Endemic Region

Cassandra Campbell, Sandra Arnold, Mario Briceno-Medina, Michael Perez, Shyam SathanandamUniversity of Pittsburgh Medical Center. Le Bonheur Children’s Hospital and University of Tennessee Health Science Center. Dell Children’s Medical Center. Nicklaus Children’s Hospital. United States Pediatric CardiologyPediatr Cardiol 2025; DOI: 10.1007/s00246-025-04123-w AbstractHistoplasmosis in children remains understudied, drawing most clinical understanding from adult populations. Located in a histoplasmosis-hyperendemic

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Clinical characteristics of children treated with high-frequency oscillation ventilation

Lihua Wen, Xiaohuan Guo, Yiyu Yang, Run Dang, Chunmin Zhang, Feiyan ChenGuangzhou Women and Children’s Medical Center and Guangzhou Medical University.China MedicineMedicine 2025; 104: DOI: 10.1097/MD.0000000000046288 AbstractHigh-frequency oscillation ventilation (HFOV) is a commonly used therapeutic modality in the pediatric intensive care unit, and this study aims to investigate the clinical characteristics of children treated with HFOV.

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Clinical and microbiological profile of pneumonia among children with congenital heart diseases at alexandria university children’s hospital

Hani Mahmoud Adel, Marwa Ahmed Meheissen, Asmaa Mahmoud Mohamed Gnina, Nirvana Mahmoud Abdel Fattah, Eman Hamza HassanAlexandria University. Egypt BioMedical Central infectious DiseasesBMC Infect Dis 2025; 25: DOI: 10.1186/s12879-025-11856-9 AbstractBackground: Pneumonia is a significant cause of morbidity and mortality among children with congenital heart diseases (CHD). Consequently, the current study aimed to identify the prevalent pathogens causing

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Pulmonary comorbidities and response to surfactant in late preterm infants: a multicenter cohort study

Iwona Sadowska-Krawczenko, Roman Hożejowski, Jan Mazela, Katarzyna Wróblewska-Seniuk, Tomasz Szczapa, Mateusz Jagła, Piotr Kruczek, Katarzyna Bierła, Renata BokiniecNicolaus Copernicus University in Torun. University Hospital No. 2 in Bydgoszcz. Chiesi Poland. Poznan University of Medical Sciences. Jagiellonian University Medical College. Czerwiakowski Hospital at Siemiradzki. District Hospital, Ostrow. Medical University of Warsaw.Poland Pediatric ResearchPediatr Res 2025;DOI: 10.1038/s41390-025-04634-5 AbstractBackground: Surfactant

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Volume Loading May Compromise Left Ventricular Filling in Patients with a Borderline Hypoplastic Left Ventricle

Machi Yamashita, Hirofumi Saiki, Kanchi Saito, Akira Sato, Seiko Kuwata, Satoshi Nakano, Hideaki Senzaki, Junichi KoizumiIwate Medical University. Nihon Institute of Medical Science.Japan International Heart JournalInt Heart J 2025; 66: 1019-1024DOI: 10.1536/ihj.25-216 AbstractGiven the high prevalence of end-organ damage in the long term after the Fontan procedure, patients presenting with borderline hypoplastic left ventricle (LV) are

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Downregulation of KLF2 impairs pulmonary endothelial function and promotes persistent pulmonary hypertension of the newborn

Ningning Chen, Xiaohang Yin, Dong Wang, Dongmei Zhou, Lili Kang, Xiaoying LiChildren’s Hospital Affiliated to Shandong University (Jinan Children’s Hospital), Cheeloo College of Medicine and Shandong University. China Biochemical PharmacologyBiochem Pharmacol 2025; DOI: 10.1016/j.bcp.2025.117572 AbstractPersistent pulmonary hypertension of the newborn (PPHN) is a severe and progressive disorder with limited therapeutic options. Dysfunction of pulmonary artery endothelial

Downregulation of KLF2 impairs pulmonary endothelial function and promotes persistent pulmonary hypertension of the newborn Read More »

Very rare combination of Pierre Robin sequence with patent ductus arteriosus, severe persistent pulmonary hypertension, and sepsis in an Afghan neonate: a case report and literature review

Mansoor Aslamzai, Turyalai Hakimi, Abdul Hakim Mukhlis, Esrar Ahmad MansooriKabul University of Medical Sciences “Abu Ali Ibni Sina”.Afghanistan Oxford Medical Case ReportsOxf Med Case Reports 2025; DOI: 10.1093/omcr/omaf235 AbstractPierre Robin sequence (PRS) is a rare congenital abnormality that may complicate serious circumstances in infants. We report a very rare case of PRS in a five-day-old Afghan

Very rare combination of Pierre Robin sequence with patent ductus arteriosus, severe persistent pulmonary hypertension, and sepsis in an Afghan neonate: a case report and literature review Read More »

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