Pediatric Pulmonary Vascular Disease

Scoping review of initiation criteria for inhaled nitric oxide in preterm infants (born <34 weeks) after 7 days of age

Shin Kato, Yohei Minamitani, Miku Hosokawa, Toshinori Nakashima, Sota Iwatani, Katsuya Hirata, Arata Oda, Takushi Hanita, Masafumi Miyata, Fumihiko Namba, Masayuki Ochiai, Atsushi Nakao, Seiji Yoshimoto, Daichi Suzuki, Erika Ota, Hidehiko Nakanishi, on behalf of the Japan Society for Neonatal Health and DevelopmentJapanese Red Cross Aichi Medical Center Nagoya Daini Hospital. Saitama Medical Center and […]

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A Delicate Balance: Anesthetic Management for Neonatal Congenital Diaphragmatic Hernia Repair

Mohamad A. Omar, Tamer Ghoneim, Hind KhaleelEmirates Health Services.United Arab Emirates CureusCureus 2024; 16:DOI: 10.7759/cureus.75506 AbstractCongenital diaphragmatic hernia (CDH) presents significant challenges in neonatal management, particularly in the context of anesthesia. This case report details the successful anesthetic management of a five-day-old neonate with left-sided CDH requiring thoracoscopic repair. A five-day-old neonate, delivered via emergency cesarean

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Endothelial Cpt1a Inhibits Neonatal Hyperoxia-Induced Pulmonary Vascular Remodeling by Repressing Endothelial-Mesenchymal Transition

Xiaoyun Li, Katy Hegarty, Fanjie Lin, Jason L. Chang, Amro Abdalla, Karthik Dhanabalan, Sergey O. Solomevich, Wenliang Song, Karim Roder, Chenrui Yao, Wenju Lu, Peter Carmeliet, Gaurav Choudhary, Phyllis A. Dennery, and Hongwei YaoBrown University. Providence VA Medical Center. Warren Alpert Medical School of Brown University. Jinan University. First Affiliated Hospital of Guangzhou Medical University.

Endothelial Cpt1a Inhibits Neonatal Hyperoxia-Induced Pulmonary Vascular Remodeling by Repressing Endothelial-Mesenchymal Transition Read More »

Conservative Pulmonary Arteriovenous Malformation Screening in Children: Re-Evaluation of Safety

Fleur ten Berg, Josefien Hessels, Anna Hosman, Sanne Boerman, Marco C. Post, Walter A. F. Balemans, Hans-Jurgen MagerSt. Antonius Hospital. University Medical Centre Utrecht. Netherlands Pediatric PulmonologyPediatr Pulmonol 2025; 60: DOI: 10.1002/ppul.27476 AbstractIntroduction: Hereditary hemorrhagic telangiectasia (HHT) is an autosomal dominant vascular disease and screening to detect pulmonary arteriovenous malformations (PAVMs) is important to prevent complications. In

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Siblings With Berardinelli-Seip Congenital Lipodystrophy: Clinical Insights and Challenges

Sri Meghana Kankipati, Surbhi Dumra, Swati Thareja, Lyluma Ishfaq, Mah N. Zargar, Arghadip Das, Sreya Kongala, Salma YounasAndhra Medical College. Employees’ State Insurance Corporation (ESIC) Medical College and Hospital. The Hans Foundation. Central Michigan University College of Medicine. Fatima Jinnah Medical University. Nilratan Sircar Medical College and Hospital. Osmania Medical College. Punjab University College of

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Pediatric Pulmonary Arterial Hypertension; is it Possible to Predict its Outcome?

Hala M. Aghaa, Ranya Hegazy, Ahmed Gamal, Ranya Essam, Antoine A. Elmessih, Ahmed Behairy,Nagib Dahdah, Ahmed Abdelwahed, Nesrine Sobhy, Noha AliSpecialized Pediatric Hospital and Cairo University. CHU Sainte Justine and University of Montreal.Egypt and Canada Journal of the Saudi Heart AssociationJ Saudi Heart Assoc 2024; 36: 408-419DOI: 10.37616/2212-5043.1398 AbstractObjectives: To assess the outcome of pediatric pulmonary arterial

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Pulmonary hypertension in infancy: a reversible cause

Cassandra Campbell, Kawaljeet Singh, Mark Weems, Panjit PhilipUniversity of Tennessee Health Science Center.United States British Medical Journals Case ReportsBMJ Case Rep 2025; 18:DOI: 10.1136/bcr-2024-263731 AbstractA term, healthy infant presented with respiratory distress and severe pulmonary hypertension (PH). With an unclear aetiology and the intent to decrease right ventricular afterload, pulmonary vasodilators were initiated. Follow-up imaging revealed

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Congenital pulmonary vein stenosis: a radiographic study

Christopher K. Adey, Benigno Soto, Myung S. ShinUniversity of Alabama School of MedicineUnited States RadiologyRadiology 1986; 161: 113-117DOI: 10.1148/radiology.161.1.3763853 AbstractSeven patients with congenital pulmonary venous stenosis were retrospectively evaluated. Chest radiographs and pulmonary angiograms were interpreted without knowledge of anatomic findings, and results were correlated with autopsy data. Bilateral foci of stenosis of varying severity were

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Spondylo-Thoracic Dysplasia: Survival, a Rare Occurrence

Upendra P. Sahu, Rufeena J, Suman Kumar, Nimisha VatsanaRajendra Institute of Medical Sciences.India CureusCureus 2024; 16: DOI: 10.7759/cureus.74894 AbstractSpondylo-thoracic dysplasia (STD) is a set of rare congenital abnormalities involving the vertebrae and thorax, leading to significant morbidity and mortality due to respiratory insufficiency and associated anomalies. Clinically, neonates present with scoliosis, vertebral segmentation defects, and severe

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Safety, tolerability, and efficacy of an in-class combination therapy switch from bosentan plus sildenafil to ambrisentan plus tadalafil in children with pulmonary arterial hypertension

Cara Morgan, Nikmah Idris, Kathy Elterefi, Luca Di Ienno, Andrew Constantine, Sadia Quyam Roberta Bini, Shahin MoledinaGreat Ormond Street Hospital for Children. Queen Elizabeth Hospital. Institute of Cardiovascular Sciences University College London. United Kingdom Pulmonary CirculationPulm Circ 2024;DOI: 10.1002/pul2.70011 AbstractThe aim of this single-centre retrospective observational study was to evaluate the safety, tolerability, and efficacy of

Safety, tolerability, and efficacy of an in-class combination therapy switch from bosentan plus sildenafil to ambrisentan plus tadalafil in children with pulmonary arterial hypertension Read More »

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