Pediatric Pulmonary Vascular Disease

Clinical impact of treprostinil in neonates with persistent pulmonary hypertension refractory to inhaled nitric oxide: A retrospective cohort study

Tae Hyeong Kim, Song Ee Youn, Sung-Hoon ChungKyung Hee University College of Medicine and Kyung Hee University Hospital at Gangdong.Republic of Korea MedicineMedicine 2026; 105: DOI: 10.1097/MD.0000000000046984 AbstractPersistent pulmonary hypertension of the newborn (PPHN) has limited options when unresponsive to inhaled nitric oxide (iNO). We evaluated the role of intravenous treprostinil and whether early response classification […]

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High-altitude pulmonary edema in children

Ralph C. Frates Jr, Gunyon M. Harrison, George A. EdwardsBaylor Collegeof Medicine and the Texas Institute for Rehabilitation and Research.United States American Journal of Diseases of ChildrenAm J Dis Child 1977; 131: 687-689DOI: 10.1001/archpedi.1977.02120190081018 AbstractA 15-year-old boy with recurrent high-altitude pulmonary edema had previously been mistakenly treated for asthma and pneumonia. Clinical manifestations of this disorder,

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High-altitude pulmonary edema in the children and young adults of Leadville, Colorado

Charles H. Scoggin, Thomas M. Hyers, John T. Reeves, Robert F. GroverUniversity of Colorado Medical Center. United States New England Journal of MedicineN Engl J Med 1977; 297: 1269-1272DOI: 10.1056/NEJM197712082972309 AbstractAbstract Not Available CategoryHigh Altitude Pulmonary Edema Age Focus: Pediatric Pulmonary Vascular Disease Fresh or Filed Publication: Filed (PHiled). Greater than 1-2 years since publication Article

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Pulmonary hypertension in pediatric patients with cystic fibrosis during acute pulmonary exacerbations: prevalence and associated factors

Zahra Roshanzamir, Fatemeh Mohammadi, Rohola ShirzadiNamazi Hospital and Shiraz University of Medical Sciences. Children’s Medical Center and Tehran University of Medical Sciences.Iran BioMedical Central Pulmonary MedicineBMC Pulm Med 2026; DOI: 10.1186/s12890-025-04095-w AbstractBackground: Cystic fibrosis (CF) is a multi-organ disorder in which respiratory complications account for the majority of its cause of mortality. This study aimed to investigate

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High-altitude pulmonary edema with absent right pulmonary artery

Billy Rios, David J. Driscoll, Dan G. McNamaraTexas Children’s Hospital and Baylor Cllege of Medicine.United States PediatricsPediatrics 1985; 75: 314-317DOI: https://doi.org/10.1542/peds.75.2.314 AbstractHigh-altitude pulmonary edema potentially is fatal. Adults with unilateral absence of a right pulmonary artery are particularly susceptible to high-altitude pulmonary edema. The occurrence of high-altitude pulmonary edema was documented in a child with

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Physical adaptation of children to life at high altitude

K. De Meer, H. S. A. Heymans, W. G. ZijlstraUniversity Children’s Hospital Het Wilhelmina Kinderziekenhuis. Beatrix Children’s Clinic and University Hospital Groningen.Netherlands European Journal of PediatricsEur J Pediatr 1995; 154: 263–272DOI: Not Availanble AbstractChildren permanently exposed to hypoxia at altitudes of > 3000 m above sea level show a phenotypical form of adaptation. Under these

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Inflammatory processes may predispose children to high-altitude pulmonary edema

Anthony G. Durmowicz, Edward Nordeweir, Richard Nicholas, John T. ReevesUniversity of Colorado Health Sciences Center.United States Journal of PediatricsJ Pediatr 1997; 130: 838-480DOI: 10.1016/s0022-3476(97)80033-9 AbstractWe investigated retrospectively whether the preexistence of inflammation-producing illnesses such as viral respiratory tract infections contributed to the development of high-attitude pulmonary edema in children. We found that the large majority of

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Viral respiratory infection increases susceptibility of young rats to hypoxia-induced pulmonary edema

Todd C. Carpenter, John T. Reeves, Anthony G. DurmowitzUniversity of Colorado Health Sciences Center.United States Journal of Applied PhysiologyJ Appl Physiol 1998; 84: 1048-1054 DOI: 10.1152/jappl.1998.84.3.1048 AbstractRecent clinical observations of a high incidence of preexisting respiratory infections in pediatric cases of high-altitude pulmonary edema prompted us to ask whether such infections would increase the susceptibility to hypoxia-induced

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Pulmonary edema in 6 children with Down syndrome during travel to moderate altitudes

Anthony G. DurmowiczUniversity of Utah Health Science Center and Primary Children’s Medical Center.United States PediatricsPediatrics 2001; 108: 443-447DOI: 10.1542/peds.108.2.443 AbstractObjective: Children with Down syndrome (DS) are living longer and are increasingly participating in recreational activities. When a child with DS was diagnosed with high-altitude pulmonary edema (HAPE), this study was undertaken to determine whether and under what

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High-altitude pulmonary edema in children with underlying cardiopulmonary disorders and pulmonary hypertension living at altitude

Bibhuti B. Das, Robert R. Wolfe, Kak-Chen Chan, Gary L. Larsen, John T. Reeves, Dunbar IvyChildren’s Hospital, Denver.United States Archives of Pediatric and Adolescent MedicineArch Pediatr Adolesc Med 2004; 158: 1170-1176DOI: 10.1001/archpedi.158.12.1170 AbstractBackground: Pulmonary hypertension has not been described as a predisposing risk factor for high-altitude pulmonary edema (HAPE) in children. Previous studies have shown an association

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