Pediatric Pulmonary Vascular Disease

Hemodynamic effects of high frequency oscillatory ventilation versus conventional mechanical ventilation in term neonates with persistent pulmonary hypertension: a single-center randomized trial

Doaa El Amrousy, Hassan Koura, Noura Abdou, Mostafa Awny, Abdelrahman ElmashadTanta University.Egypt Italian Journal of MedicineItal J Med 2026; 52: DOI: 10.1186/s13052-026-02272-z AbstractBackground: We aimed to evaluate the hemodynamics in full-term neonates with persistent pulmonary hypertension (PPH) on high frequency oscillatory ventilation (HFOV) versus conventional mechanical ventilation (CMV).Methods: This trial was conducted on 64 full-term neonates with PPH […]

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Pulmonary arterial hypertension in infancy: A case series

N. V. Shashikala, K. M. Arun, R. C. Ashwini, Muganagowda PatilBapuji Child Health Institute and Research Centre. India Tropical DoctorTrop Doct 2026;DOI: 10.1177/00494755261451113 AbstractThiamine deficiency is a reversible cause of severe pulmonary arterial hypertension (PAH) in early infancy, particularly among exclusively breastfed infants of mothers consuming polished rice-based diets. This retrospective case series (July 2023-July 2025)

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The preponderance of genetic variations in paediatric pulmonary hypertension

Julien Grynblat, Melanie Eyries, Marine Ambar-Akkaoui, Marilyne Levy, Mathilde Meot, Isabelle Szezepanski, Julien Ranchoup, Alessia Callegari, Julie Karila-Cohen, Caroline Bonnet, Pierre Marijon, Jerome Champ, Florence Coulet, Caroline Ovaert, Frederic Perros, Fabrice Antigny, Pascale Maragnes, Guy Vaksmann, Marc Humbert, Sophie Guiti Malekzadeh Milani, David Montani Damien BonnetHôpital Necker-Enfants malades, AP-HP, Université de Paris Cité, Université Paris-Saclay,

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Gap between guidelines and practice: echocardiography reporting in neonatal pulmonary hypertension

Sophia Gremont, Eveliina Ronkainen, Merja KallioUniversity of Oulu. Oulu University Hospital. Helsinki University Hospital, University of Helsinki.Finland Cardiology in the YoungCardiol Young 2026; DOI: 10.1017/S104795112611292X AbstractObjectives: Targeted neonatal echocardiography is increasingly integrated into neonatal care and plays a crucial role in the evaluation and management of persistent pulmonary hypertension of the newborn. The objective of this study

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Pediatric pulmonary hypertension registry: Single-center experience from India

Wadile Santosh, Mishra Arpita, Banpurkar Ashishkumar Moreshwar, Raeen Shahena Parveen, Kulkarni SnehalSri Sathya Sai Sanjeevani Centre for Child Heart Care and Training in Pediatric Cardiac Skills.India Annals of Pediatric CardiologyAnn Pediatr Cardiol 2026; 19: 14-22DOI: 10.4103/apc.apc_181_24 AbstractBackground: Pulmonary hypertension (PH) is a rare and usually irreversible disease, eventually leading to right heart failure (RHF). There are multiple

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Surgical management of complex congenital heart diseases in the context of South-South cooperation: case series

Laurence Carole Ngo Yon, Hermann Nestor Tsague Kengni, Godwin Sharau, Deogratias Nkya, Stella Mongella, Flora Fondjo, Alex Loth, Vivienne Mlawi, Salvatore AgatiUniversity of Yaounde I. Yaounde General Hospital. Jakaya Kikwete Cardiac Institute. Catholic University of Central Africa. San Vincenzo Hospital in Taormina.Cameroon, Tanzania and Italy PanAfrican Medical JournalPan Afr Med J 2026; 53: DOI: 10.11604/pamj.2026.53.21.49748 AbstractComplex

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Antenatally diagnosed severe congenital pulmonary airway malformation requiring life-saving lobectomy in the early neonatal period: A case report

Maroua El Ouaer, Hayet Ben Hamida, Tasnim Frigui, Seifeddine Ben Hammouda, Samia Bel Hssan, Amina Ben SalemUniversity of Monastir. Teaching Hospital of Monastir. Tunisia Radiology Case ReportsRadiol Case Rep 2026; 21: 3039-3045DOI: 10.1016/j.radcr.2026.04.025 AbstractCongenital pulmonary airway malformation (CPAM) ranges from asymptomatic lesions to life-threatening neonatal presentations. Large lesions can lead to severe respiratory failure requiring urgent

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Hepatopulmonary syndrome as presentation of pediatric metabolic dysfunction-associated steatohepatitis

Shruti Sakhuja, Stacey S. Beer, Kalyani R. Patel, Alexiss M. Williams, Nhu Thao Galvan, John A. Goss, Krupa R. MysoreBaylor College of Medicine and Texas Children’s Hospital. United States Journal of Pediatric Gastroenterolgy and Nutrition ReportsJPGN Rep 2026; 7: 362-365DOI: 10.1002/jpr3.70139 AbstractChildhood obesity is rising and leading to serious co-morbidities, among which is metabolic dysfunction-associated steatotic

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Safety of Sildenafil in Premature Infants with Severe Bronchopulmonary Dysplasia (SILDI-SAFE): A Randomized Controlled Trial

Wesley M. Jackson, Henry P. Foote, Nicole Stephenson, Steven M. Kemp, Ryan T. Moore, Christopher R. Nitkin, Dan Stewart, Gloria S. Pryhuber, John T. Berger, Ankita Shukla, Amand England, Stephanie M. Ford, Lance A. Parton, Jennifer F. Check, Mina H. Hanna, Megan Lagoski, Ramesh Krishnan, Kristen T. Leeman, Shilpa Vyas-Read, Mark L. Hudak, Anup C.

Safety of Sildenafil in Premature Infants with Severe Bronchopulmonary Dysplasia (SILDI-SAFE): A Randomized Controlled Trial Read More »

Experience with selexipag in triple therapy for pulmonary arterial hypertension in Chinese children

Meng Li, Yingchun Wang, Xiaoyu Hu, Haizhao Zhao, Weida Lu, Yuan Ji, Xiaopei CuiQilu Hospital and Cheeloo College of Medicine of Shandong University. China BioMedical Central PediatricsBMC Pediatr 2026; DOI: 10.1186/s12887-026-06954-9 AbstractBackground: Selexipag is an orally effective prostacyclin receptor agonist that has been approved for treating pulmonary arterial hypertension (PAH) in adults but is still used off-label

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