Pediatric Pulmonary Vascular Disease or Adult Pulmonary Vascular Disease

NLRP3 Inflammasome Triggers Inflammation of Obstructive Sleep Apnea

Xiaoting Yangzhong, Shu Hua, Yiqiong Wen, Xiaoqing Bi, Min Li, Yuanyuan Zheng, Shibo SunFirst Affiliated Hospital, Kunming Medical University.China Current Molecular MedicineCurr Mol Med 2024; DOI: 10.2174/0115665240294605240426123650 AbstractObstructive sleep apnea [OSA] is widespread in the population and affects as many as one billion people worldwide. OSA is associated with dysfunction of the brain system that controls […]

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Splenectomy is significantly associated with thrombosis but not with pulmonary hypertension in patients with transfusion-dependent thalassemia: a meta-analysis of observational studies

Tsampika-Vasileia Kalamara, Konstantino Dodos, Efthymia VlachakiHippokration General Hospital and Aristotle University of Thessaloniki.Greece Frontiers in MedicineFront Med 2023; 10: DOI: 10.3389/fmed.2023.1259785 AbstractIntroduction: Thromboembolism (TE) and pulmonary hypertension (PH) constitute frequently occurring complications in patients with transfusion-dependent thalassemia and have been associated with splenectomy in different studies. Nevertheless, the size of the possible association varies greatly in literature. Herein,

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Dynamically stiffening biomaterials reveal age- and sex-specific differences in pulmonary arterial adventitial fibroblast activation

Mikala C. Mueller, Yanmei Du, Lori A. Walker, Chelsea M. MaginUniversity of Colorado, Anschutz Medical Campus.United States Matrix Biology PlusMatrix Biol Plus 2024; DOI: 10.1016/j.mbplus.2024.100145 AbstractRespiratory diseases like pulmonary arterial hypertension (PAH) frequently exhibit sexual dimorphism. Female PAH patients are more susceptible to the disease but have increased survival rates. This phenomenon is known as the

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Inhaled NO at a crossroads in cardiac surgery: current need to improve mechanistic understanding, clinical trial design and scientific evidence

Stefan Muenster, Iratxe Zarragoikoetxea, Andrea Moscatelli, Joan Balcells, Philippe Gaudard, Philippe Pouard, Nandor Marczin, Stefan P. JanssensUniversity Hospital Bonn. Hospital Universitari I Politècnic Fe. IRCCS Istituto Giannina Gaslini. Universitari Vall d’Hebron. University of Montpellier. Assistance Publique-Hopitaux de Paris and Hopital Necker-Enfants Malades. Imperial College. University Hospital Leuven.Germany, Spain, Italy, France, United Kingdom and Belgium Frontiers

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Environmental pollutants exposure-derived extracellular vesicles: crucial players in respiratory disorders

Haoran Shen, Rui Zheng, Mulong Du, David C. ChristianiNanjing Medical University. Harvard T.H. Chan School of Public Health. Massachusetts General Hospital.China and United States ThoraxThorax 2024; DOI: 10.1136/thorax-2023-221302 AbstractBackground: Individual exposure to environmental pollutants, as one of the most influential drivers of respiratory disorders, has received considerable attention due to its preventability and controllability. Considering that the

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Causal association of depression, anxiety, cognitive performance, the brain cortical structure with pulmonary arterial hypertension: A Mendelian randomization study

Zeying Zhang, Shelby Kutty, Wei Peng, Gaoming Zeng, Haiyan Luo, Zhenghui Xiao, Qiming Liu, Yunbin XiaoSecond Xiangya Hospital of Central South University. Johns Hopkins School of Medicine. Hunan Children’s Hospital. China Journal of Affective DisordersJ Affect Dis 2024;DOI: 10.1016/j.jad.2024.01.276 AbstractBackground: Patients with pulmonary arterial hypertension (PAH) often present with anxiety, depression and cognitive deterioration. Structural changes in

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Low global arginine bioavailability: a common phenomenon in pulmonary hypertension

Dunia Hatabah, Teresa De Marco, Dana P. McGlothlin, Mary Malloy, Loretta Z. Reyes, Rawan Korman, Gregory J. Kato, Claudia R. MorrisEmory University School of Medicine. University of California, San Francisco. Kaiser Permanente San Francisco. Children’s Healthcare of Atlanta. Blood Science Consulting.United States American Journal of Physiology Lung Cellular and Molecular PhysiologyAm J Physiol Lung Cell

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The Paradox of Pulmonary Vascular Resistance: Restoration of Pulmonary Capillary Recruitment as a Sine Qua Non for True Therapeutic Success in Pulmonary Arterial Hypertension

David Langleben, Stylianos E. Orfanos, Benjamin D. Fox, Nathan Messas, Michele Giovinazzo, John D. CatravasJewish General Hospital and McGill University. Evangelismos Hospital and National and Kapodistrian University of Athens Medical School. Yitzchak Shamir Hospital and Tel Aviv University. Old Dominion University.Canada, Greece, Israel and United States Journal of Clinical MedicineJ Clin Med 2022; 11:DOI: 10.3390/jcm11154568 AbstractExercise-induced

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Viewing Pulmonary Hypertension Through a Pediatric Lens

Stuti Agarwal, Jeffrey Fineman, David N. Cornfield, Cristina M. Alvira, Roham T. Zamanian, Kara Goss, Ke Yuan, Sebastien Bonnet, Olivier Boucherat, Soni Pullamsetti, Miguel A. Alcázar, Elena Goncharova, Tatiana V. Kudryashova, Mark R. Nicolls, Vinicio de Jesús PérezStanford University. University of California, San Francisco. University of Texas Southwestern. Boston Children’s Hospital. University of Laval. Max-Planck-Institute

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Isolated Partial Anomalous Pulmonary Veins: A 10-Year Experience at a Single Center

Can Jin, Yongtao Wu, Zhiyi Wang, Xiaoran Liu, Qiang WangBeijing An Zhen Hospital Affiliated with Capital University of Medical Sciences. China Journal of Surgical ResearchJ Surg Res 2024; 298: 63-70DOI: 10.1016/j.jss.2023.12.022 AbstractIntroduction: Isolated partial anomalous pulmonary venous connection (PAPVC) is difficult to diagnose, and surgical indications remain controversial. We reviewed 10 y of isolated PAPVC cases.Methods: The data

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