Pediatric Pulmonary Vascular Disease or Adult Pulmonary Vascular Disease

A unique gut microbiota signature in pulmonary arterial hypertension: A pilot study

Arun Jose, Senu Apewokin, Walaa E. Hussein, Nicholas J. Ollberding, Jean M. Elwing, David B. HaslamUniversity of Cincinnati. Cincinnati Children’s Hospital Medical Center.United States Pulmonary CirculationPulm Circ 2022; 12: DOI: 10.1002/pul2.12051 AbstractPulmonary arterial hypertension (PAH) is a progressive, ultimately fatal cardiopulmonary disease associated with a number of physiologic changes, which is believed to result in imbalances […]

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Endothelin-1 gene polymorphism (G8002A) and endothelial monocyte-activating polypeptide II: Role in vascular dysfunction in pediatric patients with β-thalassemia major

Azza Abdel Gawad Tantawy, Mourad Alfy Ramzy Tadros, Amira Abdel Moneam Adly, Eman Abdel Rahman Ismail, Fatma A. Ibrahim, Nanis Mohammed Salah Eldin, Mahitab Morsy Hussein, Mervat Abdalhameed Alfeky, Sarah Mohammed Ibrahim, Marwa Adel Hashem, Fatma Soliman Elsayed EbeidAin Shams University. Military Medical Services and Military Medical Academy.Egypt CytokineCytokine 2023; 161: DOI: 10.1016/j.cyto.2022.156048 AbstractBackground: Endothelin-1 (ET-1), a potent endogenous vasoconstrictor, stimulates production of reactive oxygen species. Endothelial monocyte-activating polypeptide-II (EMAP-II) is a multifunctional polypeptide.Aim: To assess ET-1 gene polymorphism

Endothelin-1 gene polymorphism (G8002A) and endothelial monocyte-activating polypeptide II: Role in vascular dysfunction in pediatric patients with β-thalassemia major Read More »

The long-term efficacy in blood transfusions, hematologic parameter changes, and complications after splenectomy in patients with transfusion-dependent thalassemia

Nichanan Osataphan, Somying Dumnil, Adisak Tantiworawit, Teerachat Punnachet, Nonthakorn Hantrakun, Pokpong Piriyakhuntorn, Thanawat Rattanathammethee, Sasinee Hantrakool, Chatree Chai-Adisaksopha, Ekarat Rattarittamrong, Lalita Norasetthada, Kanda Fanhchaksai, Pimlak CharoenkwanChiang Mai University. Thailand Transfusion and Apheresis ScienceTransfus Apher Sci 2022; DOI: 10.1016/j.transci.2022.103620 AbstractBackground: A splenectomy can reduce transfusion requirements in patients with thalassemia. However, the role of a splenectomy remains controversial

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Hemodynamic Characteristics After Fontan Procedure in Patients with Down’s Syndrome

Masakazu Otsuka, Yoshihiko Kodama, Ayako Kuraoka, Yuichi Ishikawa, Makoto Nakamura, Toshihide Nakano, Hideaki Kado, Shintaro Umemoto, Ayako Ishikita, Ichiro Sakamoto, Tomomi Ide, Hiroyuki Tsutsui, Koichi SagawaFukuoka Children’s Hospital. Kyushu University Hospital.Japan Pediatric CardiologyPediatr Cardiol 2022; 43: 360-365DOI: 10.1007/s00246-021-02727-6 AbstractPatients with Down’s syndrome (DS) are generally regarded as not being good candidates for the Fontan procedure. However,

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Case Report: A Rare Syncope Case Caused by Abernethy II and a Review of the Literature

Xue-qin Lin, Jing-yi Rao, Yi-fei Xiang, Li-wei Zhang, Xiao-ling Cai, Yan-song Guo, Kai-yang LinShengli Clinical Medical College of Fujian Medical University and Fujian Provincial Hospital. Fujian Clinical Medical Research Center for Cardiovascular Diseases.China Frontiers in Cardiovascular DiseaseFront Cardiovasc Dis 2022; 8: DOI: 10.3389/fcvm.2021.784739 AbstractBackground: Abernethy malformation is an extremely rare anomaly of the splanchnic venous system, and

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Development of a PET/MRI exercise stress test for determining cardiac glucose dependence in pulmonary arterial hypertension

Gregory P. Barton, Philip A. Corrado, Christopher J. Francois, James R. Runo, Naomi C. Chesler, Alan B. McMillan, Oliver Wieben, Kara N. GossUniversity of Wisconsin. University of Texas Southwestern Medical Center. University of California-Irvine. United States Pulmonary CirculationPulm Circ 2022; DOI: 10.1002/pul2.12025 AbstractNo Abstract Available CategoryClass I. Pulmonary Hypertension Associated with Connective Tissue DiseasePulmonary Hypertension Associated

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Long-term outcomes of living-donor lobar lung transplantation

Seiichiro Sugimoto, Hiroshi Date, Kentaroh Miyoshi, Shinji Otani, Megumi Ishihara, Masaomi Yamane, Shinichi ToyookaOkayama University Hospital. Kyoto University Graduate School of Medicine.Japan Journal of Thoracic and Cardiovascular SurgeryJ Thorac Cardiovasc Surg 2022; 164: 440-448DOI: 10.1016/j.jtcvs.2021.08.090 AbstractObjective: Although living-donor lobar lung transplantation (LDLLT) enables an intermediate survival similar to cadaveric lung transplantation, the long-term outcome remains unknown. We

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Pulmonary vasodilator therapies in pulmonary arterial hypertension associated with CHD: a systematic review and network meta-analysis

Jun Yasuhara, Kae Watanabe, Atsuyuki Watanabe, Takuro Shirasu, Yuichi Matsuzaki, Hirofumi Watanabe, Hisato Takagi, Naokata Sumitomo, Toshiki KunoNationwide Children’s Hospital. Ann & Robert H. Lurie Children’s Hospital of Chicago and Northwestern University Feinberg School of Medicine. University of Tsukuba Hospital. University of Virginia. McGill University. Medical University of South Carolina. Shizuoka Medical Center. Saitama Medical

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Sex as an Independent Risk Factor for Venous Thromboembolism in Sickle Cell Disease: A Cross-Sectional Study

Andrea H. Roe, Arden McAllister, Corinne Kete, Hilary Whitworth, Courtney A. Schreiber, Farzana A. SayaniUniversity of Pennsylvania Perelman School of Medicine. The Children’s Hospital of Philadelphia.United States Journal of Women’s HealthJ Womens Health 2022; 31: 1467-1471DOI: 10.1089/jwh.2022.0046 AbstractVenous thromboembolism (VTE) affects up to 25% of individuals with sickle cell disease (SCD), but risk factors are not

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Implications for the metabolic fate of oral glutamine supplementation within plasma and erythrocytes of patients with sickle cell disease: A pharmacokinetics study

Claudia R. Morris, Frans A. Kuypers, Robert Hagar, Sandra Larkin, Lisa Lavrisha, Augusta Saulys, Elliott P. Vichinsky, Jung H. SuhEmory University School of Medicine and Children’s Healthcare of Atlanta. UCSF-Benioff Children’s Hospital Oakland.United States Complementary Therapies in MedicineComplement Ther Med 2022; 64: DOI: 10.1016/j.ctim.2022.102803 AbstractObjectives: L-Glutamine is FDA-approved for sickle cell disease (SCD), yet the mechanism(s)-of-action are

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