Pediatric Pulmonary Vascular Disease or Adult Pulmonary Vascular Disease

Congenital descending aorta to pulmonary vein fistula: an unusual cause of left ventricular dilation in a 21-year-old female

Xiang Pan, Chan Yu, Zhouhui Chen, Bowen ZhaoSir Run Run Shaw Hospital and Zhejiang University College of Medicine.China Journal of Cardiothoracic SurgeryJ Cardiothorac Surg 2025; 20: DOI: 10.1186/s13019-025-03691-5 AbstractBackground: Congenital descending aorta to pulmonary vein fistula (cDAPVF) is a rare congenital vascular malformation diagnosed in infancy and childhood. Adult cDAPVF is often asymptomatic and usually detected incidentally […]

Congenital descending aorta to pulmonary vein fistula: an unusual cause of left ventricular dilation in a 21-year-old female Read More »

Targeting CircNLRP12 attenuates hypoxia-induced pulmonary arterial smooth muscle cell dysfunction by sponging miR-107-5p and suppressing the ITGA2-mediated FAK/PI3K/AKT pathway

Zongbin Li, Miao Zhao, Shanshan Ma, Shuyu LeiThird People’s Hospital of Xinjiang Uygur Autonomous Region. China European Journal of Medical ResearchEur J Med Res 2025; DOI: 10.1186/s40001-025-03586-0 AbstractBackground: Pulmonary arterial hypertension associated with congenital heart disease (PAH-CHD) drives lethal pulmonary vascular remodeling. While circular RNAs (circRNAs) are emerging as disease regulators, their functional roles in PAH-CHD remain

Targeting CircNLRP12 attenuates hypoxia-induced pulmonary arterial smooth muscle cell dysfunction by sponging miR-107-5p and suppressing the ITGA2-mediated FAK/PI3K/AKT pathway Read More »

A rare case of isolated unilateral pulmonary vein atresia presenting as interstitial lung disease in a young adult

Arnav Shandil, Mansi Verma, Sushma Makhaik, Sumala KapilaIndira Gandhi Medical CollegeIndia Journal of Cardiovascular and Thoracic ResearchJ Cardiovasc Thorac Res 2025; 17: 212-214DOI: 10.34172/jcvtr.025.33139 AbstractUnilateral pulmonary vein atresia is an unusual congenital cardiovascular abnormality. It occurs due to failure of incorporation of pulmonary veins into the left atrium. It is usually diagnosed in childhood and diagnosis

A rare case of isolated unilateral pulmonary vein atresia presenting as interstitial lung disease in a young adult Read More »

The relation between Down syndrome and co-occurring conditions in children and young adults: A population-based cohort in Denmark, 1977-2016

Cheng Yin, Chuanjie Deng, Catherine M. Crespi, Sari Bar, Chandra D. Carey, M. Elizabeth Brickner, Eugenia Chock, Erin C. Schafer, Igor Barjaktarevic, Kosuke Inoue, Johnni Hansen, Julia E. HeckUniversity of North Texas. University of California, Los Angeles. University of Texas Southwestern Medical Center. University of Pittsburgh. Yale School of Medicine. Graduate School of Medicine of

The relation between Down syndrome and co-occurring conditions in children and young adults: A population-based cohort in Denmark, 1977-2016 Read More »

Are NONO Variants Linked to Congenital Heart Disease? Patient Reports and Review

Peiqing He, Sini Zou, Jianxiong Chen, Meiyi Wang, Peng Lin, Jiwu Lou, Zhanying Ma, Zhen Li, Tizhen YanDongguan Maternal and Child Health Care Hospital. China European Journal of Medical GeneticsEur J Med Genet 2025; DOI: 10.1016/j.ejmg.2025.105060 AbstractPathogenic variants in the NONO gene (MIM #300084) are responsible for X-linked syndromic intellectual developmental disorder-34 (MRXS34, MIM #300967) characterized

Are NONO Variants Linked to Congenital Heart Disease? Patient Reports and Review Read More »

Dermatologic findings in hereditary hemorrhagic telangiectasia: association with epistaxis, visceral involvement, and genetics

Andrea Michelerio, Giuseppe Spinozzi, Chiara Giorgini, Carla Olivieri, Annalisa de Silvestri, Fabio Pagella, Camilla VassalloUniversity of Pavia. Fondazione IRCCS Policlinico San Matteo. Italy Italian Journal of Dermatology and VenereologyItal J Dermatol Venereol 2025; DOI: 10.23736/S2784-8671.25.08225-8 AbstractBackground: Hereditary hemorrhagic telangiectasia (HHT) is a genetic vascular disorder characterized by epistaxis, mucocutaneous telangiectasias, and visceral arteriovenous malformations (AVMs). Despite the

Dermatologic findings in hereditary hemorrhagic telangiectasia: association with epistaxis, visceral involvement, and genetics Read More »

Clinical profile and long-term outcomes of pediatric-onset Takayasu’s arteritis: data from a mexican national referral center

Dilcia Paola Pagoaga-Vásquez, Gabriela Melendez-Ramírez, Emilia Josefina Patiño-Bahena, Alfonso Buendia-Hernández, Edgar Samuel Ramírez-Marroquín, Juan Eberto Calderon-Colmenero, Solange Gabriela Koretzky, Guering Eid-Lit, María Elena SotoInstituto Nacional de Cardiología Ignacio Chávez. Hospital Infantil de México “Federico Gómez”.  Centro Médico ABC Sur. Mexico Pediatric Rheumatology Online JournalPediatr Rheumatol Online J 2025; 23: DOI: 10.1186/s12969-025-01145-9 AbstractBackground: Takayasu arteritis (TA) is a

Clinical profile and long-term outcomes of pediatric-onset Takayasu’s arteritis: data from a mexican national referral center Read More »

Platelet-Macrophage Aggregates in Remodeled Vessels of Patients With Pulmonary Arterial Hypertension

Christine L. Farrell, Mariah Jordan, Janelle N. Posey, Kimberly R. Jordan, Aneta Gandjeva, Eva S. Nozik, Kurt R. Stenmark, Rubin M. Tuder, Brian B. Graham, Cassidy A. DelaneyUniversity of Colorado Anschutz Medical Campus and Children’s Hospital Colorado. University of California San Francisco.United States Pulmonary CirculationPulm Circ 2025; 15: DOI: 10.1002/pul2.70174 AbstractUsing lung immunohistochemistry and stereology, platelets

Platelet-Macrophage Aggregates in Remodeled Vessels of Patients With Pulmonary Arterial Hypertension Read More »

Association Between Steady-State Lactate Dehydrogenase Levels and Sickle Cell Complications: A Systematic Review

Sagad O.O. Mohamed, Amged Mohammed, Fatima S.K. Salih, Hozifa A.M. Elgadal, Ayman A.A. Elsamany, Mohamed S.K. Salih, Huda M.A. Mustafa, Israa Elawad, Mona G.A. Ahmedkaroum, Safaa G.A. Saeed, Rowa E.A. Ibrahim, Esraa A. Mohamedien, Aya A.H. Babiker, Esraa T. Suliman, Eman O.E. MohamedUniversity of Khartoum. Médecins Sans Frontières. University of Bahri. Ibri Regional Hospital. Harlem

Association Between Steady-State Lactate Dehydrogenase Levels and Sickle Cell Complications: A Systematic Review Read More »

Fenfluramine and Comparative Antiseizure Therapies in Drug-Resistant Epilepsy: A Systematic Review of Efficacy, Cardiometabolic Safety, and Clinical Outcomes

Ashis Pal, Bhavna Singla, Shivam Singla, Muhammad Habib Ur Rehman, Ali Hamza, Ahmad Mohammad, Momina Abid, Aqib ImranDhaka National Medical Institute Hospital. Erie County Medical Center Hospital. TidalHealth Peninsula Regional. King Edward Medical University. Hurley Medical Center. Madinah Teaching Hospital. Nishtar Medical University.Bangladesh, United States and Pakistan CureusCureus 2025; 17: DOI: 10.7759/cureus.91949 AbstractFenfluramine has emerged as

Fenfluramine and Comparative Antiseizure Therapies in Drug-Resistant Epilepsy: A Systematic Review of Efficacy, Cardiometabolic Safety, and Clinical Outcomes Read More »

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