Review Articles Concerning Pulmonary Vascular Disease

Respiratory Support Strategies for Surgical Neonates: A Review

Piero Alberti, Niyi Ade-Ajayi, Anne GreenoughKing’s College London.United Kingdom ChildrenChildren 2025; 12: DOI: 10.3390/children12030273 AbstractNeonates with congenital conditions which require surgical management frequently experience respiratory distress. This review discusses the management of pulmonary complications and the respiratory support strategies for four conditions: oesophageal atresia-tracheoesophageal fistula (OA-TOF), congenital diaphragmatic hernia (CDH), congenital lung malformations (CLM), and anterior […]

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Omphalocele and Associated Anomalies: Exploring Pulmonary Development and Genetic Correlations-A Literature Review

Dina Al Namat, Romulus Adrian Ros, Razan Al Namat, Elena Hanganu, Andrei Ivan, Delia Hînganu, Ancut Lupu, Marius Valeriu HînganuUniversity of Medicine and Pharmacy “Grigore T. Popa”. “Saint Mary” Emergency Children HospitalRomania DiagnosticsDiagnostics 2025; 15: DOI: 10.3390/diagnostics15060675 AbstractOmphalocele is a rare congenital abdominal wall defect, occurring in approximately 3.38 per 10,000 pregnancies. It is characterized by

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Contemporary treatment of right ventricular failure

Bibhuti B. Das, Shashi RajUniversity of Mississippi Medical Center. Narayana Health.United States and India Journal of Heart and Lung Transplantation OpenJHLT Open 2025; 7: DOI: 10.1016/j.jhlto.2024.100203 AbstractRight ventricular failure (RVF) is a clinical syndrome resulting from structural and functional changes in the right ventricle (RV), leading to inadequate blood flow to the pulmonary circulation and elevated

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Trametinib as a targeted treatment in cardiac and lymphatic presentations of Noonan syndrome

Isabel De Brouchoven, Juan Lorand, Léon Bofferding, Arthur Sorlin, An Van Damme, Olivier DanhaiveSaint-Luc University Hospital,. Luxembourg Hospital Center. Laboratoire National de Santé. University of California San Francisco.Belgium, Luxembourg and United States Frontiers in PediatricsFront Pediatr 2025; 13: DOI: 10.3389/fped.2025.1475143 AbstractIntroduction: Rare pathogenic variants in the PTPN11, KRAS, SOS1 and RAF1 genes are the main molecular causes of Noonan syndrome (NS).

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Hemodynamic precision to guide surgical timing for neonates with congenital diaphragmatic hernia: a narrative review

John T. Wren, Neil Patel, Matthew T. Harting, Patrick J. McNamaraUniversity of Iowa Hospitals and Clinics. Royal Hospital for Children. McGovern Medical School at the University of Texas Health Science Center and Children’s Memorial Hermann Hospital. United States and United Kingdom Journal of PerinatologyJ Perinatol 2025; DOI: 10.1038/s41372-025-02265-6 AbstractDespite a near universal approach focused on physiologic

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Macitentan: Pediatric First Approval

Susan J. KeamSpringer Nature.New Zealand Paediatric DrugsPaediatr Drugs 2025; DOI: 10.1007/s40272-025-00692-8 AbstractMacitentan (Opsumit®), an endothelin receptor antagonist (ERA) developed by Johnson & Johnson, is well established worldwide as monotherapy or combination therapy for the long-term treatment of pulmonary arterial hypertension (PAH). In September 2024, based on phase 3 clinical data in patients aged < 18 years,

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Reverse Potts shunt in severe pulmonary hypertension: A 20-year retrospective review

Wei Jiang, Zhongshi Wu, Can Huang, Ting Lu, Haoyong Yuan, Yuhong Liu, Tao QianSecond Xiangya Hospital of Central South University.China International Journal of CardiologyInt J Cardiol 2025; DOI: 10.1016/j.ijcard.2025.133129 AbstractPulmonary arterial hypertension (PAH) is a multifactorial heterogeneous condition characterized by elevated pulmonary artery pressure, leading to increased right ventricular afterload and ultimately resulting in right heart

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A Comprehensive Review of Pediatric Obstructive Sleep Apnea: From Assessment to Intervention

Ulhas Jadhav, Jay Bhanushali, Arman Sindhu, Bingu Shiv Kiran Reddy, Amit Toshniwal, Mummaneni RashmikaJawaharlal Nehru Medical College and Datta Meghe Institute of Higher Education and Research.India CureusCureus 2025; 17: DOI: 10.7759/cureus.78051 AbstractPediatric obstructive sleep apnea (OSA) is a prevalent sleep disorder characterized by upper airway obstruction during sleep, leading to oxygen desaturation and sleep disruptions. This

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Fetoscopic Endoluminal Tracheal Occlusion-Synergic Therapies in the Prenatal Treatment of Congenital Diaphragmatic Hernia

Zsolt Bara, Horea Gozar, Nándor Nagy, Simona Gurzu, Zoltán Derzsi, Timea Forró, Evelyn Kovács, Ioan JungGeorge Emil Palade University of Medicine, Pharmacy, Science and Technology of Targu Mures. County Emergency Clinical Hospital. Semmelweis University. Romanian Academy of Medical Sciences.Romania and Hungary International Journal of Molecular SciencesInt J Mol Sci 2025; 26: DOI: 10.3390/ijms26041639 AbstractCongenital diaphragmatic hernia

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Growing Up with Developmental Lung Diseases: A Review for the Adult Pulmonologist

Yadira Rivera-Sanchez, Zachary W. Blair, Tyler J. Wall, Kara N. GossUniversity of Texas Southwestern Medical Center.United States ChestChest 2025; DOI: 10.1016/j.chest.2025.02.014 AbstractTopic importance: Improved childhood management strategies have decreased the early life morbidity and mortality of severe developmental lung disorders, such that an increasing number of individuals ultimately transition care to adult pulmonologists for management. Alternatively, individuals

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