Review Articles Concerning Pulmonary Vascular Disease

Caring for the smallest hearts: cardiovascular phenotypes and assessment in tiny babies

Srirupa Hari Gopal, Shweta Parmekar, Eugene Dempsey, Mohan PammiSSM Health Cardinal Glennon Children’s Hospital and Saint Louis University. Baylor College of Medicine and Texas Children’s Hospital.  University College Cork.United States and Ireland Pediatric ResearchPediatr Res 2026; DOI: 10.1038/s41390-026-05164-4 AbstractWith improving survival, periviable neonates (≤25 weeks’ gestation) represent a dynamic, but under-studied population in neonatal care, with […]

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Risk Stratification and Fetal Therapies for Congenital Diaphragmatic Hernia

Connor V. Haynes, David H. StitelmanYale New Haven Children’s Hospital,United States NeoreviewsNeoreviews 2026; DOI: 10.1542/neo.27-6-021 AbstractCongenital diaphragmatic hernia (CDH) remains one of the most challenging congenital anomalies encountered by neonatologists and pediatric surgeons, with outcomes largely determined before birth. Although surgical repair of the diaphragmatic defect is essential, postnatal morbidity and mortality are primarily driven by

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Breathing challenges in achondroplasia: a comprehensive review of pediatric respiratory complications

Veronica Fasoli, Alessia Mariani, Federica Chironi, Mara Lelii, Barbara Madini, Beatrice Andrenacci, Alessia Rocchi, M. Francesca Bedeschi, M. Gaffuri, M. Pluderi, M. Francesca PatriaUniversità Degli Studi di Milano. Fondazione IRCCS Ca’ Granda Ospedale Maggiore Policlinico. Italy Paediatric Respiratory ReviewsPaediatr Respir Rev 2026; DOI: 10.1016/j.prrv.2026.05.003 AbstractAchondroplasia is the most common skeletal dysplasia, characterized by disproportionate short stature

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Association between upper airway obstruction and pulmonary hypertension in children with Down syndrome

Kevin Guy, Amal IsaiahUniversity of Maryland School of Medicine.United States Current Opinion in Pulmonary MedicineCurr Opin Pulm Med 2026; DOI: 10.1097/MCP.0000000000001287 AbstractPurpose of review: Down syndrome (DS) is the most common nonlethal chromosomal aneuploidy, affecting 1 in 700 live births. Pulmonary hypertension (PH) occurs in approximately 25% of children with DS and contributes to a 10% mortality

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Therapeutic Targets for Pediatric Pulmonary Vein Stenosis: Insights from Animal Models

Siqi She, Debao Li, Qi Sun, Lincai YeShanghai Children’s Medical Center and Shanghai Jiao Tong University School of Medicine. Children’s Hospital of Fudan University and National Children’s Medical Center. China ChildrenChildren 2026; 13: DOI: 10.3390/children13050677 AbstractPulmonary vein stenosis (PVS) is a rare and devastating condition affecting infants and children, characterized by progressive intimal hyperplasia, myofibroblast proliferation,

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Recent advances in the clinical management of end-stage pediatric pulmonary hypertension

Oscar van der Have, Rachel K. Hopper, Rebecca J. Kameny, Karin Tran-LundmarkLund University and Skane University Hospital. Stanford University School of Medicine.Sweden and United States Current Opinion in Pulmonary MedicineCurr Opin Pulm Med 2026; DOI: 10.1097/MCP.0000000000001283 AbstractPurpose of review: This review aims to give an overview of recent advances in the clinical management of children <18 years

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Evolving Concepts in Pulmonary Hypertension: Implementation challenges of the current guidelines and proceedings in the US

Sandeep Sahay, Rodolfo A. Estrada, Megan Griffiths, Naomi Habib, Sandhya Murthy, Steven D. Nathan, Rachel T. Sullivan, James R. Klinger, Raymond BenzaHouston Methodist Hospital. UT Health San Antonio. Children’s Medical Center Dallas and University of Texas Southwestern. Norton Thoracic Institute. Montefiore-Einstein Heart Center. Inova Fairfax Hospital. Monroe Carell Jr. Children’s Hospital and Vanderbilt University. Rhode

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Sickle cell disease-associated pulmonary hypertension: an integrated framework linking pathologies, mechanisms, and clinical phenotypes

Florence Vallelian, Dominik J. Schaer, Benoit Lechartier, Paul W. Buehler, David C. IrwinUniversity of Zurich. Lausanne University Hospital and University of Lausanne. University of Maryland. Anschutz Medical Campus School of Medicine and University of Colorado. Switzerland and United States eBioMedicineeBioMedicine 2026; DOI: 10.1016/j.ebiom.2026.106288 AbstractSickle cell disease-associated pulmonary hypertension (SCD-PH) affects approximately 10% of adults with SCD

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Transcatheter Interventional Options in Pulmonary Vein Stenosis: When to Stent?

Heidi Van Christopher J. Petit, Oliver M. BarryColumbia University Vagelos College of Physicians and Surgeons and NewYork-Presbyterian Hospital Morgan Stanley Children’s HospitalUnited States Seminars in Thoracic and Cardiovascular Surgery Pediatric Cardiac Surgery AnnualSemin Thorac Cardiovasc Surg Pediatr Card Surg Ann 2026;DOI: 10.1053/j.pcsu.2026.02.007 AbstractPulmonary vein stenosis (PVS) is a rare and aggressive condition in infants and children,

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Pulmonary Vein Stenosis Medical Therapy: Current and on the Horizon

Mudit Gupta, David B. FrankPerelman School of Medicine at the University of Pennsylvania and Children’s Hospital of PhiladelphiaUnited States Seminars in Thoracic and Cardiovascular Surgery Pediatric Cardiac Surgery AnnualSemin Thorac Cardiovasc Surg Pediatr Card Surg Ann 2026;DOI: 10.1053/j.pcsu.2026.02.006 AbstractPulmonary vein stenosis (PVS) is a severe vascular obstructive lesion historically associated with poor survival. As outcomes have

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