Review Articles Concerning Pulmonary Vascular Disease

Pediatric Pulmonary Arteriovenous Malformations in Patients with Hereditary Hemorrhagic Telangiectasia: Screening, Diagnosis, and Management

Claire S. Kaufman, Minh Anh Nguyen, Amy Bezold, Mark S. ChesnuttOregon Health and Science University. United States Journal of Clinical MedicineJ Clin Med 2025; 14: DOI: 10.3390/jcm14113739 AbstractPulmonary arteriovenous malformations (PAVMs) are abnormal communications between a pulmonary artery and pulmonary vein that bypass the capillary bed, resulting in right-to-left shunting. The majority of PAVMs are associated […]

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Mitochondrial cardiomyopathies: navigating through different clinical and management pictures between adult and paediatric forms

Rachele Adorisio, Nicoletta Cantarutti, Barbara Siri, Elisa Bellettini, Gessica Ingrasciotta, Erica Mencarelli, Francesca Graziani, Rosa Lillo, Sara Di Marzio, Corrado Di Mambro, Fabrizio Drago, Antonio Amodeo, Diego MartinelliBambino Gesù Children’s Hospital. University of Turin. Fondazione Policlinico Universitario A. Gemelli.Italy Frontiers in Cardiovascular MedicineFront Cardiovasc Med 2025; 12: DOI: 10.3389/fcvm.2025.1621096 AbstractMitochondrial diseases (MD) represent a group of

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Enhancing Drug Development for Paediatric Pulmonary Hypertension-An Integrative Perspective

Steven H. Abman, Sylvia M. Nikkho, Rolf M. F. Berger, Maria Jesus del Cerro, Eric D. Austin, Maurice Beghetti, Dunbar Ivy, Megan Griffiths, Anne Hilgendorff, Steven H. Kawut, Usha S. Krishnan, Mary P. Mullen, Shahin Moledina, Bernard Thébaud, Norman StockbridgeUniversity of Colorado School of Medicine and Children’s Hospital Colorado. Bayer AG. Beatrix Children’s Hospital, University

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Prematurity and obstructive sleep apnea in children: The perfect storm

Oscar Camilo Pantoja-Gomez, Juanita Agudelo-Agudelo, Elida Duenas-Meza, Sonia M. Restrepo-Gualteros, Maria J. Gutierrez, Gustavo NinoUniversidad de La Sabana. Universidad Nacional de Colombia. Johns Hopkins University. Children’s National Hospital and George Washington University School of Medicine and Health Sciences.Columbia and United States Paediatric Respiratory ReviewsPaediatr Respir Rev 2025; DOI: 10.1016/j.prrv.2025.06.001 AbstractAs survival rates for premature infants improve,

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Cardiovascular protective properties of the natural product eugenol

Xin-yu Liu, Yun-ke Nie, Yang Liu, Mei ChenClinical College of Qilu Medical University. China European Journal of PharmacologyEur J Pharmacol 2025;DOI: 10.1016/j.ejphar.2025.177929 AbstractMedicinal herbs have long been used in traditional medicine and their multi-featured bioactivities against the pathophysiology of chronic diseases are currently being extensively investigated in both experimental and clinical settings. Eugenol, a versatile small

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Cardiorespiratory transition in CDH

Deepika Sankaran. Satyan Lakshminrusimha, Michelle J. LimUniversity of California, Davis.United States Seminars in Fetan and Neonatal MedicineSemin Fetal Neonatal Med 2025; DOI: 10.1016/j.siny.2025.101649 AbstractCongenital diaphragmatic hernia (CDH) is a rare congenital anomaly that occurs due to incomplete closure of the diaphragm followed by herniation of abdominal contents into the chest. Fetal hemodynamics are altered in CDH

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Insights from precision-cut lung slices-investigating mechanisms and therapeutics for pulmonary hypertension

William R. Studley, Emma Lamanna, Claudia A. Nold‑Petry, Cheng Xue Qin, Jane E. BourkeMonash University. Hudson Institute of Medical Research. Baker Heart and Diabetes Institute. Australia. Respiratory ResearchRespir Res 2025; 26: DOI: 10.1186/s12931-025-03290-x AbstractPrecision-cut lung slices (PCLS) are gaining traction as a versatile ex vivo tool to study mechanisms and treatments for lung diseases. This preparation,

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Fetal therapy for congenital diaphragmatic hernia: past, present and future

Nimrah Abbasi, Tim Van Mieghem, Greg RyanMount Sinai Hospital and University of Toronto.Canada World Journal of Pediatric SurgeryWorld J Pediatr Surg 2025;DOI: 10.1136/wjps-2024-000835 AbstractCongenital diaphragmatic hernia (CDH) affects 1/2500-5000 infants and is associated with significant neonatal morbidity and mortality related to pulmonary hypoplasia and pulmonary hypertension. Current estimates of perinatal mortality are between 30-40%. With advances

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Oxygen Saturation Targeting in the Neonatal Intensive Care Unit

Faeq Almudares, Bheru Gandhi, Jonathan Davies, Xanthi Couroucli, Natalie Villafranco, Nidhy Paulose Varghese, Milenka Cuevas Guaman, Charleta Guillory, Binoy ShivannaBaylor College of Medicine.United States Journal of Clinical MedicineJ Clin Med 2025; 14: DOI: 10.3390/jcm14113975 AbstractOxygen (O2) is vital for cellular development, function, proliferation, and repair, underscoring its critical role in organogenesis. Both hypoxia (reduced tissue O2)

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Down syndrome and congenital heart disease: perioperative planning and management

Dennis R. Delany, Stephanie S. Gaydos, Deborah A. Romeo, Heather T. Henderson, Kristi L. Fogg, Angela S. McKeta, Minoo N. Kavarana, John M. CostelloMedical University of South Carolina. United States Journal of Congenital CardiologyJ Congenit Cardiol 2021; 5: DOI: 10.1186/s40949-021-00061-3 AbstractApproximately 50% of newborns with Down syndrome have congenital heart disease. Non-cardiac comorbidities may also be

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