Review Articles Concerning Pulmonary Vascular Disease

Recent advances in the clinical management of end-stage pediatric pulmonary hypertension

Oscar van der Have, Rachel K. Hopper, Rebecca J. Kameny, Karin Tran-LundmarkLund University and Skane University Hospital. Stanford University School of Medicine.Sweden and United States Current Opinion in Pulmonary MedicineCurr Opin Pulm Med 2026; DOI: 10.1097/MCP.0000000000001283 AbstractPurpose of review: This review aims to give an overview of recent advances in the clinical management of children <18 years

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Evolving Concepts in Pulmonary Hypertension: Implementation challenges of the current guidelines and proceedings in the US

Sandeep Sahay, Rodolfo A. Estrada, Megan Griffiths, Naomi Habib, Sandhya Murthy, Steven D. Nathan, Rachel T. Sullivan, James R. Klinger, Raymond BenzaHouston Methodist Hospital. UT Health San Antonio. Children’s Medical Center Dallas and University of Texas Southwestern. Norton Thoracic Institute. Montefiore-Einstein Heart Center. Inova Fairfax Hospital. Monroe Carell Jr. Children’s Hospital and Vanderbilt University. Rhode

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Sickle cell disease-associated pulmonary hypertension: an integrated framework linking pathologies, mechanisms, and clinical phenotypes

Florence Vallelian, Dominik J. Schaer, Benoit Lechartier, Paul W. Buehler, David C. IrwinUniversity of Zurich. Lausanne University Hospital and University of Lausanne. University of Maryland. Anschutz Medical Campus School of Medicine and University of Colorado. Switzerland and United States eBioMedicineeBioMedicine 2026; DOI: 10.1016/j.ebiom.2026.106288 AbstractSickle cell disease-associated pulmonary hypertension (SCD-PH) affects approximately 10% of adults with SCD

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Transcatheter Interventional Options in Pulmonary Vein Stenosis: When to Stent?

Heidi Van Christopher J. Petit, Oliver M. BarryColumbia University Vagelos College of Physicians and Surgeons and NewYork-Presbyterian Hospital Morgan Stanley Children’s HospitalUnited States Seminars in Thoracic and Cardiovascular Surgery Pediatric Cardiac Surgery AnnualSemin Thorac Cardiovasc Surg Pediatr Card Surg Ann 2026;DOI: 10.1053/j.pcsu.2026.02.007 AbstractPulmonary vein stenosis (PVS) is a rare and aggressive condition in infants and children,

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Pulmonary Vein Stenosis Medical Therapy: Current and on the Horizon

Mudit Gupta, David B. FrankPerelman School of Medicine at the University of Pennsylvania and Children’s Hospital of PhiladelphiaUnited States Seminars in Thoracic and Cardiovascular Surgery Pediatric Cardiac Surgery AnnualSemin Thorac Cardiovasc Surg Pediatr Card Surg Ann 2026;DOI: 10.1053/j.pcsu.2026.02.006 AbstractPulmonary vein stenosis (PVS) is a severe vascular obstructive lesion historically associated with poor survival. As outcomes have

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Advances in the pathogenesis and clinical management of pulmonary hypertension

Yi Yan, Zhuoyuan Xu, Yanghanyue Zhou, Xike Wang, Hao ZhangShanghai Children’s Medical Center, National Children’s Medical Center and Shanghai Jiao Tong University School of Medicine. Guizhou Branch of Shanghai Children’s Medical Center and Guizhou Provincial People’s Hospital.China Medical ReviewMed Rev 2026; 6: 120-141DOI: 10.1515/mr-2026-0002 AbstractPulmonary hypertension (PH) is a severe cardiopulmonary disorder characterized by pulmonary vascular

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Sotatercept in Children with Pulmonary Hypertension-A Narrative Review

Johanna Schulz, Veronika C. Stark, Lars Harbaum, Rainer Kozlik-Feldmann, Thomas S. Mir, Fridrike Stute, Jakob OlfeUniversity Heart & Vascular Center Hamburg. University Medical Centre Hamburg-Eppendorf Hamburg.Germany ChildrenChildren 2026; 13: DOI: 10.3390/children13040465 AbstractBackground/objectives: Pulmonary arterial hypertension (PAH) is a rare but life-threatening disease that presents particular therapeutic challenges in children. It is characterized by pulmonary vasoconstriction and vascular

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The Importance of Sex as a Biological Variable in Pulmonary Vascular Research

Mikala Mueller, Sue Gu, Krithika Lingappan, R. Blair Dodson, Chelsea M. MaginUniversity of Colorado. Children’s Hospital of Philadelphia and University of Pennsylvania. Research Triangle Institute International.United States American Journal of Physiology Lung Cellular and Molecular PhysiologyAm J Physiol Lung Cell Mol Physiol 2026; DOI: 10.1152/ajplung.00036.2026 AbstractSex differences shape disease susceptibility, progression, and therapeutic response across human

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Bronchopulmonary Dysplasia: A Contemporary Review for Pediatric Practice

Marie Berg, Silvia Maria del Rocio Delgado-Villalta, Catalina BazacliuUniversity of Florida College of Medicine. United States Pediatrics in ReviewPediatr in Rev 2026; DOI: 10.1542/pir.2024-006701 AbstractBronchopulmonary dysplasia (BPD) remains a significant source of morbidity and mortality among preterm infants, especially those born before 28 weeks gestation. Although the survival of preterm infants has improved, the incidence of

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Pathogenesis, Evaluation, and Management of Pulmonary Vein Stenosis: JACC Review Topic of the Week

Trevor Simard, Dhruv Sarma, William R. Miranda, Charles Jain, Jason H. Anderson, Jeremy D. Collins, Abdallah El Sabbagh, Aravdeep Jhand, Tobias Peikert, Guy S. Reeder, Thomas M. Munger, Douglas L. Packer, David R. HolmesMayo Clinic.United States Journal of the American College of CardiologyJ Am Coll Cardiol 2023; 81: 2361-2373DOI: 10.1016/j.jacc.2023.04.016 AbstractPulmonary vein stenosis (PVS) can arise

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