Review Articles Concerning Pulmonary Vascular Disease

Persistent Pulmonary Hypertension of the Newborn: A Pragmatic Review of Pathophysiology, Diagnosis, and Advances in Management

Karolina Chojnacka, Yogen Singh, Sheen Gahlaut, Witold Blaz, Agata Jerzak, Tomasz SzczapaPoznan University of Medical Sciences. University of California and UC Davis Children’s Hospital. Oxford University. Saint Jadwiga the Queen Clinical Provincial Hospital and University of Rzeszow.Poland, United States and United Kingdom BiomedicinesBiomedicines 2025; 13: DOI: 10.3390/biomedicines13102332 AbstractPersistent pulmonary hypertension of the newborn (PPHN) results from […]

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Vascular and Non-Vascular Intervention in the Pediatric Chest: An Update

Sunit Davda, Ajit Yadav, Manish Patel, Matt HawkinsGreat Ormond Street Hospital. Sir Ganga Ram Hospital. Cincinnati Children’s Hospital Medical Center. Emory University School of Medicine and Children’s Healthcare of Atlanta.United Kingdom, India and United States CardioVascular and Interventional RadiologyCardiovasc Interv Radiol 2025; DOI: 10.1007/s00270-025-04226-0 AbstractIn pediatric patients, thoracic intervention can involve aerodigestive tract, pleura, pulmonary parenchymal,

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Role of lipid droplets in pulmonary arterial hypertension: focusing on pulmonary artery smooth muscle cell proliferation

Baishi Huang, Yu Hao, Zhe Wen, Jie Dong, Shengwei Jin, Hui LiSecond Affiliated Hospital, Yuying Children’s Hospital and Wenzhou Medical University. China Lipids in Health and DiseaseLipids Health Dis 2025; 24:DOI: 10.1186/s12944-025-02746-9 AbstractPulmonary arterial hypertension (PAH) is a devastating disease complicated by pathological features such as proliferation of pulmonary artery smooth muscle cells (PASMCs), vasoconstriction, increased

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“Gentle” cardio-respiratory management in congenital diaphragmatic hernia: Time for a precision-medicine approach?

Anna Foth, David Tingay, Florian KipfmuellerUniversity Medical Center Mannheim and Heidelberg University. Murdoch Children’s Research Institute and University of Melbourne. Germany and Australia Seminars in Fetal and Neonatal MedicineSemin Fetal Neonatal Med 2025; DOI: 10.1016/j.siny.2025.101660 AbstractCongenital diaphragmatic hernia (CDH) remains one of the most challenging conditions to manage in neonatal intensive care, with outcomes determined by

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Chronic Lung Disease-Related Pulmonary Hypertension in Children

Jason E. Lang, Kevin D. HillDuke Clinical Research Institute and Duke University School of Medicine. United States Acta PaediatricaActa Paediatr 2025; DOI: 10.1111/apa.70320 AbstractAim: Pulmonary hypertension (PH) is characterised by elevated pressures in the pulmonary arterial system. Despite its high mortality, paediatric PH has few approved treatments. Our aim was to review the latest diagnostic and treatment

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Pharmacology in Congenital Diaphragmatic Hernia: A Focus on Cardiovascular Management

Anie Lapointe, Florian Kipfmueller, Neil Patel, Gabriel AltitCHU Sainte-Justine. University Medical Center Mannheim and University of Heidelberg. Royal Hospital for Children. Montreal Children’s Hospital and McGill University Health Centre Research Institute.Canada, Germany and United Kingdom NeoreviewsNeoreviews 2025; 26: e660-e678DOI: 10.1542/neo.26-10-060 AbstractCongenital diaphragmatic hernia (CDH) presents a complex challenge in neonatal care, requiring tailored pharmacological strategies to

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Bronchopulmonary dysplasia, pulmonary hypertension, and neonatal gastroesophageal reflux: Association, causation, or neither?

Erik A. JensenStanford University School of Medicine and Lucile Packard Children’s Hospital.United States Seminars in PerinatologySemin Perinatol 2025; DOI: 10.1016/j.semperi.2025.152158 AbstractBronchopulmonary dysplasia (BPD) is among the most common and serious complications of prematurity. The pathobiology of BPD and BPD associated pulmonary arterial hypertension (BPD-PH) is multifactorial and not yet fully defined. Gastroesophageal reflux (GER), a physiologic

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Technical Challenges in Studying Infectious Disease-Associated Pulmonary Hypertension in Low- and Middle-Income Countries with Limited Resources

Jennifer van Heerden, Irina Mbanze, Elizabeth Louw, Olukayode Aremu, Anastase Dzudie, Ana Mocumbi, Threnesan Naidoo, Brian Allwood, Friedrich ThienemannUniversity of Oxford. Maputo Central Hospital. University of Cape Town. University of Stellenbosch. Douala General Hospital. Universidade Eduardo Mondlane. Walter Sisulu University. University of Zurich.United Kingdom, Mozambique, South Africa, Cameroon and Switzerland Infectious Disease ReportsInfect Dis Rep

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Optimizing ECLS strategies in the management of congenital diaphragmatic hernia: Recent advances and best practices

Kylie Holden, Devin Saljuud, Kevin Johnson, Matthew T. HartingMcGovern Medical School at the University of Texas Health Science Center. Vanderbilt University.United States Seminars in Fetal and Neonatal MedicineSemin Fetal Neonatal Med 2025; DOI: 10.1016/j.siny.2025.101659 AbstractInfants with congenital diaphragmatic hernia (CDH) face severe pulmonary hypoplasia, pulmonary hypertension, and cardiac dysfunction, making it one of the most challenging

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Use of atrial flow regulator device in children and patients with CHD: a literature review

Fausto Frazzetto, Enrico Piccinelli, Mara Pilati, Micol Rebonato, Gianfranco ButeraBambino Gesù Children’s Hospital. Politecnico di Torino. Italy Cardiology in the YoungCardiol Young 2025; DOI: 10.1017/S1047951125109463 AbstractThe Occlutech Atrial Flow Regulator is a self-expandable double-disc nitinol device with a central fenestration designed to create a calibrated communication across the interatrial septum. It has been used in adult

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