Pathogenesis, Evaluation, and Management of Pulmonary Vein Stenosis: JACC Review Topic of the Week

Trevor Simard, Dhruv Sarma, William R. Miranda, Charles Jain, Jason H. Anderson, Jeremy D. Collins, Abdallah El Sabbagh, Aravdeep Jhand, Tobias Peikert, Guy S. Reeder, Thomas M. Munger, Douglas L. Packer, David R. Holmes
Mayo Clinic.
United States

Journal of the American College of Cardiology
J Am Coll Cardiol 2023; 81: 2361-2373
DOI: 10.1016/j.jacc.2023.04.016

Abstract
Pulmonary vein stenosis (PVS) can arise from several etiologies, including congenital, acquired, and iatrogenic sources. PVS presents insidiously, leading to significant delays in diagnosis. A high index of suspicion and dedicated noninvasive evaluation are key to diagnosis. Once diagnosed, both noninvasive and invasive evaluation may afford further insights into the relative contribution of PVS to symptoms. Treatment of underlying reversible pathologies coupled with transcatheter balloon angioplasty and stenting for persistent severe stenoses are established approaches. Ongoing refinements in diagnostic modalities, interventional approaches, postintervention monitoring, and medical therapies hold promise to further improve patient outcomes.

Category
Segmental Pulmonary Venous Disease. Without a Focus on Pulmonary Hypertension
Review Articles Concerning Pulmonary Vascular Disease

Age Focus: Pediatric Pulmonary Vascular Disease or Adult Pulmonary Vascular Disease

Fresh or Filed Publication: Filed (PHiled). Greater than 1-2 years since publication

Article Access
Free PDF File or Full Text Article Available Through PubMed or DOI: Yes

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