Class 3. Pulmonary Hypertension Associated with Lung Hypoplasia

Less is More: ECMO Utilization and Outcomes in Congenital Diaphragmatic Hernia

Anastasia M. Kahan, Sommer Glasgow, Bradley A. Yoder, Michelle Yang, Christian C. Yost, Kelsea Peterson, Jack H. Scaife, Christopher E. Clinker, Erica Arnold, Stephen J. Fenton, Zachary J. Kastenberg, Robert A. Swendiman, Scott S. Short, Katie W. RussellUniversity of Utah.United States Journal of Pediatric SurgeryJ Pediatr Surg 2025; DOI: 10.1016/j.jpedsurg.2025.162571 AbstractPurpose: Infants with congenital diaphragmatic hernia (CDH) […]

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Case Report: Tracheobronchomalacia after a two-stage surgical approach to treat congenital diaphragmatic hernia with hepatopulmonary fusion

Juri Kanda, Takeo Mukai, Chiharu Irisa, Kyosuke Ibi, Rina Matsuda, Kaori Morita, Akio Ishiguro, Masako Ikemura, Yosuke Yamada, Hisaya Hasegawa, Jun Fujishiro, Naoto TakahashiUniversity of Tokyo Hospital. Tokyo Women’s Medical University Adachi Medical Center.Japan Frontiers in PediatricsFront Pediatr 2025; 13: DOI: 10.3389/fped.2025.1573827 AbstractHepatopulmonary fusion (HPF) is a rare comorbidity of right-sided congenital diaphragmatic hernia (CDH). The

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Cardiac function in children with congenital diaphragmatic hernia: cardiac strain at birth and at 2-5 weeks of age

Katarina Övermo Tydén, Kerstin Magnusson, Carmen Mesas Burgos, Baldvin Jonsson, Felicia NordenstamKarolinska Institutet and Karolinska University Hospital.Sweden Frontiers in PediatricsFront Pediatr 2025; 13: DOI: 10.3389/fped.2025.1598695 AbstractIntroduction: Neonates with congenital diaphragmatic hernia (CDH) often present with pulmonary hypertension and various forms of cardiac dysfunction, affecting right or left ventricle or both. Although pulmonary hypertension typically improves over time,

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Impact of Pulmonary Hypertension and Patent Ductus Arteriosus in Preterm Infants with Presumed Pulmonary Hypoplasia

Sol Kim, Yumi Seo, Moon-Yeon Oh, Min Soo Kim, Sook Kyung YumSeoul St. Mary’s Hospital and Catholic University of Korea.Republic of Korea BiomedicinesBiomedicines 2025; 13: DOI: 10.3390/biomedicines13071725 AbstractObjectives: Pulmonary hypertension and hemodynamically significant PDA (hsPDA) involve seemingly opposite physiological features-decreased pulmonary blood flow and pulmonary overcirculation, respectively-but the literature demonstrates variable respiratory consequences in association with

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Giant Omphalocele: Systematic Review of Pulmonary Complications and Implications for Neonatal Care

Joana Peixoto, Joana Neto, Susana Pissarra, Inês Azevedo, Henrique Soares, Gustavo RochaUniversidade do Porto. Centro Hospitalar Universitário de São João. Portugal European Journal of Pediatric SurgeryEur J Pediatr Surg 2025; DOI: 10.1055/a-2649-0781 AbstractThe primary objectives were to know the prevalences of pulmonary hypoplasia (PH), persistent pulmonary hypertension of the newborn (PPHN), and mortality in newborn infants

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Initial Survival and Short-term Pulmonary Comorbidities in Infants with Congenital Diaphragmatic Hernia of Differing Indices of Social Determinants of Health

Yeu Sanz Wu, Alysala Malik, Chunhui Wang, Christian Welch, Caitlin J. Cain-Trivette, Christopher Nemeh, Nicholas Schmoke, Paul Kurlansky, Usha S. Krishnan, Avila De, Vincent Duron Columbia University Irving Medical Center/NewYork Presbyterian Morgan Stanley Children’s Hospital and Columbia University Vagelos College of Physicians & Surgeons. United States Journal of Pediatric SurgeryJ Pediatr Surg 2025; DOI: 10.1016/j.jpedsurg.2025.162460 AbstractPurpose: To

Initial Survival and Short-term Pulmonary Comorbidities in Infants with Congenital Diaphragmatic Hernia of Differing Indices of Social Determinants of Health Read More »

Cardiorespiratory transition in CDH

Deepika Sankaran. Satyan Lakshminrusimha, Michelle J. LimUniversity of California, Davis.United States Seminars in Fetan and Neonatal MedicineSemin Fetal Neonatal Med 2025; DOI: 10.1016/j.siny.2025.101649 AbstractCongenital diaphragmatic hernia (CDH) is a rare congenital anomaly that occurs due to incomplete closure of the diaphragm followed by herniation of abdominal contents into the chest. Fetal hemodynamics are altered in CDH

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Critical Care Dilemma: Complex Congenital Pulmonary Airway Malformation With Pulmonary Hypertension in a Neonate

Sajjad M. AlKadhem, Ali T. Alattas, Hadeel AlJubab, Abdulwahhab S. AlJubabKing Fahad Medical City.Saudi Arabia CureusCureus 2025; 17: DOI: 10.7759/cureus.85279 AbstractCongenital pulmonary airway malformations (CPAMs) are the most prevalent congenital lung lesions, yet their postnatal trajectory remains heterogeneous. Although many antenatally detected macrocystic lesions remain clinically silent, rapid postnatal enlargement can precipitate tension physiology, air-leak syndromes,

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Revisiting Inhaled Nitric Oxide Utilization in Congenital Diaphragmatic Hernia: A National Cohort Study of Major Children’s Hospitals in the United States

Anne M. Sescleifer, Charbel Chidiac, Zane J. Hellmann, Katherine M. McDermott, Alejandro V. Garcia, Daniel S. Rhee, Mark B. Slidell, Daniel G. Solomon, Shauen M. KunisakiJohns Hopkins University School of Medicine. Yale School of Medicine.United States Journal of Pediatric SurgeryJ Pediatr Surg 2025; DOI: 10.1016/j.jpedsurg.2025.162423 AbstractPurpose: For over a decade, there has been evidence suggesting a lack

Revisiting Inhaled Nitric Oxide Utilization in Congenital Diaphragmatic Hernia: A National Cohort Study of Major Children’s Hospitals in the United States Read More »

Fetal therapy for congenital diaphragmatic hernia: past, present and future

Nimrah Abbasi, Tim Van Mieghem, Greg RyanMount Sinai Hospital and University of Toronto.Canada World Journal of Pediatric SurgeryWorld J Pediatr Surg 2025;DOI: 10.1136/wjps-2024-000835 AbstractCongenital diaphragmatic hernia (CDH) affects 1/2500-5000 infants and is associated with significant neonatal morbidity and mortality related to pulmonary hypoplasia and pulmonary hypertension. Current estimates of perinatal mortality are between 30-40%. With advances

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