Class 3. Pulmonary Hypertension Associated with Lung Hypoplasia

Critical Care Dilemma: Complex Congenital Pulmonary Airway Malformation With Pulmonary Hypertension in a Neonate

Sajjad M. AlKadhem, Ali T. Alattas, Hadeel AlJubab, Abdulwahhab S. AlJubabKing Fahad Medical City.Saudi Arabia CureusCureus 2025; 17: DOI: 10.7759/cureus.85279 AbstractCongenital pulmonary airway malformations (CPAMs) are the most prevalent congenital lung lesions, yet their postnatal trajectory remains heterogeneous. Although many antenatally detected macrocystic lesions remain clinically silent, rapid postnatal enlargement can precipitate tension physiology, air-leak syndromes, […]

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Revisiting Inhaled Nitric Oxide Utilization in Congenital Diaphragmatic Hernia: A National Cohort Study of Major Children’s Hospitals in the United States

Anne M. Sescleifer, Charbel Chidiac, Zane J. Hellmann, Katherine M. McDermott, Alejandro V. Garcia, Daniel S. Rhee, Mark B. Slidell, Daniel G. Solomon, Shauen M. KunisakiJohns Hopkins University School of Medicine. Yale School of Medicine.United States Journal of Pediatric SurgeryJ Pediatr Surg 2025; DOI: 10.1016/j.jpedsurg.2025.162423 AbstractPurpose: For over a decade, there has been evidence suggesting a lack

Revisiting Inhaled Nitric Oxide Utilization in Congenital Diaphragmatic Hernia: A National Cohort Study of Major Children’s Hospitals in the United States Read More »

Fetal therapy for congenital diaphragmatic hernia: past, present and future

Nimrah Abbasi, Tim Van Mieghem, Greg RyanMount Sinai Hospital and University of Toronto.Canada World Journal of Pediatric SurgeryWorld J Pediatr Surg 2025;DOI: 10.1136/wjps-2024-000835 AbstractCongenital diaphragmatic hernia (CDH) affects 1/2500-5000 infants and is associated with significant neonatal morbidity and mortality related to pulmonary hypoplasia and pulmonary hypertension. Current estimates of perinatal mortality are between 30-40%. With advances

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Congenital diaphragmatic hernia with congenital heart disease including ventricular septal defect: Risk factors

Yuichi Hirano, Keita Terui, Wataru Kudo, Ayako Takenouchi, Shugo Komatsu, Saroru Oita, Hiroko Yoshizawa, Takashi Fumita, Yusaku Yoshino, Tomoro HishikiChiba University Graduate School of Medicine.Japan Pediatric InternationalPediatr Int 2025; DOI: 10.1111/ped.70126 AbstractBackground: Congenital diaphragmatic hernia (CDH) with congenital heart disease (CHD) has a poor prognosis. This study aimed to establish the prognostic factors of CDH associated with

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Infant lung transplantation: First German experience including two cases of ABO blood group incompatible transplantations

Anna Katharina Zürn, Nicolaus Schwerk, Carsten Müller, Gregor Warnecke, Jawad Salman, Michael Sasse, Harald Köditz, Thomas Jack, Bettina Bohnhorst, Gesine Hansen, Oliver Keil, Katja Nickel, Dmitry Bobylev, Fabio Ius, Julia CarlensHannover Medical School. University Hospital of Schleswig-Holstein. Germany Journal of Heart and Lung Transplantation OpenJHLT Open 2025; 9: DOI: 10.1016/j.jhlto.2025.100251 AbstractBackground: Infant lung transplantation (LuTx) has been

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The nitrofen/bisdiamine murine model of congenital diaphragmatic hernia has a pulmonary hypertension vascular phenotype consistent with human CDH

Cailin R. Gonyea, Yuanjun Shen, Katherine M. Nelson, Rylie N. Bird, Rachel M. Gilbert, Oluyinka O. Olutoye II, Sundeep G. Keswani, Jason P. GleghornUniversity of Delaware. Baylor College of Medicine.United States American Journal of Physiology Lung Cellular and Molecular PhysiologyAm J Physiol Lung Cell Mol Physiol 2025; DOI: 10.1152/ajplung.00233.2024 AbstractCDH-associated pulmonary hypertension (CDH-PH) has severe implications

The nitrofen/bisdiamine murine model of congenital diaphragmatic hernia has a pulmonary hypertension vascular phenotype consistent with human CDH Read More »

Combined extracorporeal membrane oxygenation support and patent ductus arteriosus ligation following surgical correction for congenital diaphragmatic hernia, a case report and literature review

Kun-Yao Hong, Zhi Zheng, Yi-Rong Zheng, Hong Liang, Liang Gao, Yu-Cong Lin, Jin-Xi Huang, Qiang Chen, Xin-Zhu LinWomen and Children’s Hospital, School of Medicine and Xiamen University. Fujian Children’s Hospital (Fujian Branch of Shanghai Children’s Medical Center), College of Clinical Medicine for Obstetrics & Gynecology and Pediatrics, Fujian Medical University.China Respiratory Medicine Case ReportsRespir Med

Combined extracorporeal membrane oxygenation support and patent ductus arteriosus ligation following surgical correction for congenital diaphragmatic hernia, a case report and literature review Read More »

Protective Effects of Bronchopulmonary Sequestration (BPS) on the Prognosis of Neonates with Congenital Diaphragmatic Hernia (CDH)

Sujin Gang, Yong Jae Kwon, Hyunhee Kwon, Suhyun Ha, Jueun Park, Byong Sop Lee, Euiseok Jung, Jiyoon Jeong, Soo Hyun Kim, Jung-Man NamgoongAsan Medical Center Children’s Hospital, Asan Medical Center and Jeonbuk National University Hospital. University of Ulsan College of Medicine. Gangneung Asan Hospital.Republic of Korea BioMedical Central PediatricsBMC Prediatr 2025; 25: DOI: 10.1186/s12887-025-05755-w AbstractBackground: Congenital diaphragmatic

Protective Effects of Bronchopulmonary Sequestration (BPS) on the Prognosis of Neonates with Congenital Diaphragmatic Hernia (CDH) Read More »

Safety and Feasibility of Early Targeted Neonatal Echocardiography and a Focused Assessment Protocol in Neonates With Congenital Diaphragmatic Hernia

John T. Wren Jr., Rachael M. Hyland, Stephanie Acosta, Patrick J. McNamaraUniversity of Iowa Healthcare.United States EchocardiographyEchocardiography 2025; DOI: 10.1111/echo.70189 AbstractObjective: Congenital diaphragmatic hernia (CDH) is a complex disease with significant morbidity and mortality. The use of echocardiography, traditionally a pediatric cardiology echocardiogram (PCE), has significantly advanced the management of CDH but its availability can be limited,

Safety and Feasibility of Early Targeted Neonatal Echocardiography and a Focused Assessment Protocol in Neonates With Congenital Diaphragmatic Hernia Read More »

Factors Associated with Early-Childhood Ipsilateral Perfusion Abnormalities among Patients with Congenital Diaphragmatic Hernia

Akila B. Ramaraj, Hannah V. Breitschopf, Kylie I. Holden, Vikas S. Gupta, Carrie L. Foster, Ashley H. Ebanks, Chase M. Miller, Terry L. Buchmiller, Matthew T. Harting, Rebecca A. Stark, CDH Study GroupSeattle Children’s Hospital and UConn Health. McGovern Medical School at the University of Texas Health Science Center and Children’s Memorial Hermann Hospital. Boston

Factors Associated with Early-Childhood Ipsilateral Perfusion Abnormalities among Patients with Congenital Diaphragmatic Hernia Read More »

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