Class 3. Pulmonary Hypertension Associated with Lung Hypoplasia

Impact of Pulmonary Hypertension and Patent Ductus Arteriosus in Preterm Infants with Presumed Pulmonary Hypoplasia

Sol Kim, Yumi Seo, Moon-Yeon Oh, Min Soo Kim, Sook Kyung YumSeoul St. Mary’s Hospital and Catholic University of Korea.Republic of Korea BiomedicinesBiomedicines 2025; 13: DOI: 10.3390/biomedicines13071725 AbstractObjectives: Pulmonary hypertension and hemodynamically significant PDA (hsPDA) involve seemingly opposite physiological features-decreased pulmonary blood flow and pulmonary overcirculation, respectively-but the literature demonstrates variable respiratory consequences in association with […]

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Giant Omphalocele: Systematic Review of Pulmonary Complications and Implications for Neonatal Care

Joana Peixoto, Joana Neto, Susana Pissarra, Inês Azevedo, Henrique Soares, Gustavo RochaUniversidade do Porto. Centro Hospitalar Universitário de São João. Portugal European Journal of Pediatric SurgeryEur J Pediatr Surg 2025; DOI: 10.1055/a-2649-0781 AbstractThe primary objectives were to know the prevalences of pulmonary hypoplasia (PH), persistent pulmonary hypertension of the newborn (PPHN), and mortality in newborn infants

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Initial Survival and Short-term Pulmonary Comorbidities in Infants with Congenital Diaphragmatic Hernia of Differing Indices of Social Determinants of Health

Yeu Sanz Wu, Alysala Malik, Chunhui Wang, Christian Welch, Caitlin J. Cain-Trivette, Christopher Nemeh, Nicholas Schmoke, Paul Kurlansky, Usha S. Krishnan, Avila De, Vincent Duron Columbia University Irving Medical Center/NewYork Presbyterian Morgan Stanley Children’s Hospital and Columbia University Vagelos College of Physicians & Surgeons. United States Journal of Pediatric SurgeryJ Pediatr Surg 2025; DOI: 10.1016/j.jpedsurg.2025.162460 AbstractPurpose: To

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Cardiorespiratory transition in CDH

Deepika Sankaran. Satyan Lakshminrusimha, Michelle J. LimUniversity of California, Davis.United States Seminars in Fetan and Neonatal MedicineSemin Fetal Neonatal Med 2025; DOI: 10.1016/j.siny.2025.101649 AbstractCongenital diaphragmatic hernia (CDH) is a rare congenital anomaly that occurs due to incomplete closure of the diaphragm followed by herniation of abdominal contents into the chest. Fetal hemodynamics are altered in CDH

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Critical Care Dilemma: Complex Congenital Pulmonary Airway Malformation With Pulmonary Hypertension in a Neonate

Sajjad M. AlKadhem, Ali T. Alattas, Hadeel AlJubab, Abdulwahhab S. AlJubabKing Fahad Medical City.Saudi Arabia CureusCureus 2025; 17: DOI: 10.7759/cureus.85279 AbstractCongenital pulmonary airway malformations (CPAMs) are the most prevalent congenital lung lesions, yet their postnatal trajectory remains heterogeneous. Although many antenatally detected macrocystic lesions remain clinically silent, rapid postnatal enlargement can precipitate tension physiology, air-leak syndromes,

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Revisiting Inhaled Nitric Oxide Utilization in Congenital Diaphragmatic Hernia: A National Cohort Study of Major Children’s Hospitals in the United States

Anne M. Sescleifer, Charbel Chidiac, Zane J. Hellmann, Katherine M. McDermott, Alejandro V. Garcia, Daniel S. Rhee, Mark B. Slidell, Daniel G. Solomon, Shauen M. KunisakiJohns Hopkins University School of Medicine. Yale School of Medicine.United States Journal of Pediatric SurgeryJ Pediatr Surg 2025; DOI: 10.1016/j.jpedsurg.2025.162423 AbstractPurpose: For over a decade, there has been evidence suggesting a lack

Revisiting Inhaled Nitric Oxide Utilization in Congenital Diaphragmatic Hernia: A National Cohort Study of Major Children’s Hospitals in the United States Read More »

Fetal therapy for congenital diaphragmatic hernia: past, present and future

Nimrah Abbasi, Tim Van Mieghem, Greg RyanMount Sinai Hospital and University of Toronto.Canada World Journal of Pediatric SurgeryWorld J Pediatr Surg 2025;DOI: 10.1136/wjps-2024-000835 AbstractCongenital diaphragmatic hernia (CDH) affects 1/2500-5000 infants and is associated with significant neonatal morbidity and mortality related to pulmonary hypoplasia and pulmonary hypertension. Current estimates of perinatal mortality are between 30-40%. With advances

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Congenital diaphragmatic hernia with congenital heart disease including ventricular septal defect: Risk factors

Yuichi Hirano, Keita Terui, Wataru Kudo, Ayako Takenouchi, Shugo Komatsu, Saroru Oita, Hiroko Yoshizawa, Takashi Fumita, Yusaku Yoshino, Tomoro HishikiChiba University Graduate School of Medicine.Japan Pediatric InternationalPediatr Int 2025; DOI: 10.1111/ped.70126 AbstractBackground: Congenital diaphragmatic hernia (CDH) with congenital heart disease (CHD) has a poor prognosis. This study aimed to establish the prognostic factors of CDH associated with

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Infant lung transplantation: First German experience including two cases of ABO blood group incompatible transplantations

Anna Katharina Zürn, Nicolaus Schwerk, Carsten Müller, Gregor Warnecke, Jawad Salman, Michael Sasse, Harald Köditz, Thomas Jack, Bettina Bohnhorst, Gesine Hansen, Oliver Keil, Katja Nickel, Dmitry Bobylev, Fabio Ius, Julia CarlensHannover Medical School. University Hospital of Schleswig-Holstein. Germany Journal of Heart and Lung Transplantation OpenJHLT Open 2025; 9: DOI: 10.1016/j.jhlto.2025.100251 AbstractBackground: Infant lung transplantation (LuTx) has been

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The nitrofen/bisdiamine murine model of congenital diaphragmatic hernia has a pulmonary hypertension vascular phenotype consistent with human CDH

Cailin R. Gonyea, Yuanjun Shen, Katherine M. Nelson, Rylie N. Bird, Rachel M. Gilbert, Oluyinka O. Olutoye II, Sundeep G. Keswani, Jason P. GleghornUniversity of Delaware. Baylor College of Medicine.United States American Journal of Physiology Lung Cellular and Molecular PhysiologyAm J Physiol Lung Cell Mol Physiol 2025; DOI: 10.1152/ajplung.00233.2024 AbstractCDH-associated pulmonary hypertension (CDH-PH) has severe implications

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