Class 3. Pulmonary Hypertension Associated with Lung Hypoplasia

Neonatologist-Performed Echocardiography in Neonatal Pulmonary Hypertension: A Narrative Review of the Literature

Anna Chiara Titolo, Mandy Ferrocino, Eleonora Biagi, Luisa Rizzo, Hajrie Seferi, Valentina Dell’Orto, Serafina Perrone, Susanna EspositoParma University Hospital and University of Parma.Italy DiagnosticsDiagnostics 2025; 15: DOI: 10.3390/diagnostics15243154 AbstractNeonatal pulmonary hypertension (PH) is a major cause of illness and death in newborns. Neonatologist-performed echocardiography (NPE) is increasingly used as a bedside tool to assess heart function, […]

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Investigation of vasoactive intestinal peptide expression and significance in a congenital diaphragmatic hernia animal model

Jiajun Chen, Huijiao Xu, Li Yang, Feifan Chen, Kunpeng Li, Bing Xu, Wenying Liu, Fang HouSichuan Provincial People’s Hospital and University of Electronic Science and Technology of China School of Medicine. China Pediatric Surgery InternationalPediatr Surg Int 2025; 42: DOI: 10.1007/s00383-025-06257-7 AbstractPurpose: To investigate vasoactive intestinal peptide (VIP) expression and distribution in fetal Sprague-Dawley (SD) rat lung

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Incidence and risk factors of pulmonary hypertension in neonates with congenital diaphragmatic hernia: a systematic review and meta-analysis

Rebeca Lopes Figueira, Fabian Doktor, Nazgol Moheimani, Giuseppe Lauriti, Jessie Lu, Giuseppe Speziale, Augusto ZaniHospital for Sick Children. Washington University School of Medicine. University of Leipzig Medical Center. “G. d’Annunzio” University of Chieti-Pescara, “Spirito Santo” Hospital of Pescara. Canada, United States, Germany and Italy Pediatric Surgery InternationalPediatr Surg Int 2025; 42: DOI: 10.1007/s00383-025-06247-9 AbstractPurpose: Pulmonary hypertension secondary

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Longitudinal changes of left ventricular hypoplasia and ventricular disproportion in congenital diaphragmatic hernia neonates

Flaminia Pugnaloni, Bartolomeo Bo, Judith Leyens, Irma Capolupo, Andrea Dotta, Pietro Bagolan, Andreas Mueller, Neil Patel, Florian KipfmuellerChildren’s Hospital, University Hospital Bonn and University of Bonn. Bambino Gesù Children’s Hospital-Research Institute, IRCCS. University Medical Center, Mannheim and Heidelberg University. University of Rome “Tor Vergata”. Royal Hospital for Children. Germany, Italy and United Kingdom Journal of

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The impact and outcome of the presence of ductus arteriosus in neonatal peripheral extracorporeal membrane oxygenation

Hsi-Yun Liu, Ming-Chou Cheng, Shao-Ju Chien, Ying-Jui Lin, Hsuan-Chang Kuo, Mei-Hsin Hsu, Chien-Te Lee, Jiunn-Jye SheuKaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine. Cheng Shiu University. Taiwan Pediatrics and NeonatologyPediatr Neonatol 2025; DOI: 10.1016/j.pedneo.2025.06.007 AbstractBackground: This study aimed to investigate the impact of the patent ductus arteriosus (DA) on pulmonary conditions and to

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Cardiology Overview of Pulmonary Hypertension Management in the Neonatal Intensive Care Unit

Rebecca J. Kameny, Rachel K. HopperStanford University.United States Clinics in PerinatologyClin Perinatol 2025; 52: 633-653DOI: 10.1016/j.clp.2025.08.002 AbstractPulmonary hypertension (PH) in the neonatal intensive care unit represents a complex and diverse spectrum of conditions, from transient persistent pulmonary hypertension of the newborn to chronic PH associated with bronchopulmonary dysplasia, congenital heart disease, and other conditions, and can

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Early left ventricular diastolic function and disease severity in congenital diaphragmatic herni

Giulia Vanina Cantone, Abhijit Bhattacharya, David Healy, Dana Levinkopf, Anna Claudia Massolo, Flaminia Pugnaloni, Giovanni Vento, Anne Marie Heuchan, Florian Kipfmueller, Neil PatelFondazione Policlinico Universitario “A. Gemelli” IRCCS and Università Cattolica del Sacro Cuore. Royal Hospital for Children. “Bambino Gesù” Children Hospital – IRCCS.  University Medical Center Mannheim and University Heidelberg.Italy, United Kingdom and Germany

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Congenital Diaphragmatic Hernia – Is there a sex specific severity phenotype?

Angeo Zarfati, Luca Pio, Arimatias Raitio, Ahmed Abu-Zaid, Khadidja Khadir, Alexandra Benachi, Paul D. LostyUniversité Paris-Saclay, Assistance Publique – Hôpitaux de Paris (AP-HP), Bicêtre Hospital. University of Rome Tor Vergata. Centre de Référence Maladie Rare. University of Turku and Turku University Hospital. Alfaisal University. Antoine Béclère Hospital. University of Liverpool. Ramathibodi Hospital, Mahidol, Mahidol University.France,

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Right-Sided Congenital Diaphragmatic Hernia: Characterization, Utility of Prenatal Imaging Predictors and Outcomes

Caitlin R. Eason, Catherine Dawson-Gore, Spencer Butted, Blair W. Weikel, Alyssa E. Vaughn, Michael Zaretsky, Marian L. Meyers, Jason Gien, Kenneth W. Liechty, S. Christopher DerderianUniversity of Colorado and Children’s Hospital Colorado. University of Arizona,United States Journal of Pediatric SurgeryJ Pediatr Surg 2025; DOI: 10.1016/j.jpedsurg.2025.162734 AbstractPurpose: Identify the most accurate prenatal predictor of survival for infants with

Right-Sided Congenital Diaphragmatic Hernia: Characterization, Utility of Prenatal Imaging Predictors and Outcomes Read More »

“Gentle” cardio-respiratory management in congenital diaphragmatic hernia: Time for a precision-medicine approach?

Anna Foth, David Tingay, Florian KipfmuellerUniversity Medical Center Mannheim and Heidelberg University. Murdoch Children’s Research Institute and University of Melbourne. Germany and Australia Seminars in Fetal and Neonatal MedicineSemin Fetal Neonatal Med 2025; DOI: 10.1016/j.siny.2025.101660 AbstractCongenital diaphragmatic hernia (CDH) remains one of the most challenging conditions to manage in neonatal intensive care, with outcomes determined by

“Gentle” cardio-respiratory management in congenital diaphragmatic hernia: Time for a precision-medicine approach? Read More »

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