Class 3. Pulmonary Hypertension Associated with Lung Hypoplasia

Are Early, Frequent Echocardiograms Necessary to Improve Outcomes of Neonates with Congenital Diaphragmatic Hernia?

Michelle J. Yang, Ryan J. Carpenter, Katie W. Russell, Stephen J. Fenton, Christian C. Yost, Bradley A. YoderUniversity of Utah School of Medicine and Primary Children’s Hospital.United States Journal of PediatricsJ Pediatr 2025; DOI: 10.1016/j.jpeds.2025.114510 AbstractObjective: To determine if timing of first postnatal echocardiogram (ECHO), early vs delayed, affects the use of extracorporeal membrane oxygenation (ECMO) and […]

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Bosentan as adjunctive therapy in neonates with congenital diaphragmatic hernia-associated pulmonary hypertension: a case series

Aster De Vadder, Lotte Lemloh, Bartolomeo Bo, Lennart Hale, Neil Patel, Andreas Mueller, Florian KipfmuellerChildren’s Hospital, University of Bonn. Royal Hospital for Children. Germany and United Kingdom European Journal of PediatricsEur J Pediatr 2025; 184: DOI: 10.1007/s00431-025-06019-6 AbstractCongenital diaphragmatic hernia (CDH)-associated pulmonary hypertension (PH) is associated with high morbidity and mortality. Pulmonary vasodilative management is challenging

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Severe pulmonary hypertension in a small-for-date neonate with skeletal dysplasia

Khuloud Mohamed, Mohammad A. A. Bayoumi, Muhammed Riyas Rahmath, Einas Elzubier ElmalikHamad Medical CorporationQatar British Medical Journals Case ReportsBMJ Case Rep 2025; 18: DOI: 10.1136/bcr-2024-264256 AbstractAbstract Not Available CategoryClass III. Pulmonary Hypertension Associated with Lung Hypoplasia Age Focus: Pediatric Pulmonary Vascular Disease Fresh or Filed Publication: Fresh (PHresh). Less than 1-2 years since publication Article Access

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Infants With a Congenital Diaphragmatic Hernia Had Favourable Pulmonary Hypertension Outcomes at 1 Year of Age

Alice Dirick, Marilyne Levy, Kelly Mellul, Maxime Coignard, Naziha Khen-Dunlop, Alexandre Lapillonne Julien Stirnemann, Elsa Kermorvant-DucheminNecker-Enfants Malades Hospital. France Acta PediatricaActa Pediatr 2025; DOI: 10.1111/apa.70019 AbstractAim: Pulmonary hypertension is frequent in neonates with a congenital diaphragmatic hernia, but long-term data have been scarce. Our aim was to examine its prevalence, evolution and management and identify factors associated

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Case Report: Respiratory outcome in a preterm infant following previable rupture of membranes and persistent oligohydramnios

Akila Subramanian, Ong Kai Zhi, Arun Kumar Pugalenthi, Victor Samuel Rajadurai, Lay Kok Tan, Suresh ChandranKK Women’s and Children’s Hospital. Lee Kong Chian School of Medicine. Duke-NUS Medical School. Yong Loo Lin School of Medicine.Singapore Frontiers in PediatricsFront Pediatr 2025; 12: DOI: 10.3389/fped.2024.1457129 AbstractMid-trimester preterm premature rupture of membranes is a rare complication of pregnancy associated

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Pulmonary Morbidity in Congenital Diaphragmatic Hernia Survivors Treated at a Non-ECMO Center From 1998 to 2015: A Cross-Sectional Study

Ulla Lei Larsen, Lone Agertoft, Anne Maria Herskind, Thomas Strøm, Palle Toft, Susanne HalkenOdense University Hospital. University of Southern Denmark. H.C. Andersen Children’s Hospital. Hospital Sønderjylland.Denmark Pediatric PulmonologyPediatr Pulmonol 2025; 60: DOI: 10.1002/ppul.27468 AbstractIntroduction: A main feature of CDH is lung hypoplasia and the related presentation of pulmonary hypertension and cardiac dysfunction. Multiple factors influence pulmonary status

Pulmonary Morbidity in Congenital Diaphragmatic Hernia Survivors Treated at a Non-ECMO Center From 1998 to 2015: A Cross-Sectional Study Read More »

Amniotic fluid stem cell extracellular vesicles as a novel fetal therapy for pulmonary hypoplasia: a review on mechanisms and translational potential

Fabian Doktor, Lina Antounians, Rebeca Lopes Figueira, Kasra Khalaj, Miriam Duci, Augusto ZaniHospital for Sick Children and University of Toronto. Leipzig University.Canada and Germany Stem Cells Translational MedicineStem Cells Transl Med 2025; 14: DOI: 10.1093/stcltm/szae095 AbstractDisruption of developmental processes affecting the fetal lung leads to pulmonary hypoplasia. Pulmonary hypoplasia results from several conditions including congenital diaphragmatic

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Postnatal management of preterm infants with congenital diaphragmatic hernia

Emma Williams, Stephanie Lau, Nimrah Abbasi, Eveline Lapidus-Krol, Priscilla P. L. Chiu, Brian T. KalishHospital for Sick Children and University of Toronto. Mount Sinai Hospital. Canada Pediatric Surgery InternationalPediatr Surg Int 2025; 41: DOI: 10.1007/s00383-025-05964-5 AbstractIntroduction: Congenital diaphragmatic hernia (CDH) in the preterm population is increasingly common in the current era of fetal endoluminal tracheal occlusion (FETO)

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Spondylo-Thoracic Dysplasia: Survival, a Rare Occurrence

Upendra P. Sahu, Rufeena J, Suman Kumar, Nimisha VatsanaRajendra Institute of Medical Sciences.India CureusCureus 2024; 16: DOI: 10.7759/cureus.74894 AbstractSpondylo-thoracic dysplasia (STD) is a set of rare congenital abnormalities involving the vertebrae and thorax, leading to significant morbidity and mortality due to respiratory insufficiency and associated anomalies. Clinically, neonates present with scoliosis, vertebral segmentation defects, and severe

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Congenital heart disease and arrhythmia disorders in newborns with congenital diaphragmatic hernia: a 23-year experience at a UK university pediatric surgical centre

Wan Teng Lee, Chun Sui Kwok, Paul D. LostyUniversity of Liverpool and Alder Hey Children’s Hospital. Ramathibodi Hospital.United Kingdom and Thailand Pediatric Surgery InternationalPediatr Surg Int 2024; DOI: 10.1007/s00383-024-05927-2 AbstractPurpose: Congenital diaphragmatic hernia (CDH) is associated with congenital heart disease (CHD) and index newborns reportedly may experience cardiac arrhythmia disorders [Tella et al.-Pediatric Critical Care Medicine 2022].

Congenital heart disease and arrhythmia disorders in newborns with congenital diaphragmatic hernia: a 23-year experience at a UK university pediatric surgical centre Read More »

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