Class 3. Pulmonary Hypertension Associated with Lung Hypoplasia

Could a Two-Staged Repair Be the Solution to the Dilemma of Repair Timing for Severe Congenital Diaphragmatic Hernia Requiring Extracorporeal Membrane Oxygenation?

Akiko YokoiKobe Children’s Hospital.Japan ChildrenChildren 2024; 11:DOI: 10.3390/children11101255 AbstractPurpose of review: Congenital diaphragmatic hernia (CDH) remains a significant challenge, particularly in severe cases with persistent pulmonary hypertension (PPHN) and hypoplastic lungs and heart. For patients unresponsive to conventional therapies, ECMO is required. While the surgical repair is relatively simple, determining the optimal timing for surgery in patients […]

Could a Two-Staged Repair Be the Solution to the Dilemma of Repair Timing for Severe Congenital Diaphragmatic Hernia Requiring Extracorporeal Membrane Oxygenation? Read More »

Ventricular Dysfunction in Patients With Congenital Diaphragmatic Hernia Who Die After Repair

Catherine M. Avitabile, Yang Wang, Devon Ash, Sabrina J. Flohr, Leny Mathew, Natalie Rintoul, Holly L. HedrickPerelman School of Medicine at the University of Pennsylvania and Children’s Hospital of Philadelphia. United States Journal of Pediatric SurgeryJ Pediatr Surg 2024; 60: DOI: 10.1016/j.jpedsurg.2024.162002 AbstractBackground: Quantitative echocardiographic (echo) measures of ventricular function predict mortality in pediatric pulmonary hypertension (PH),

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Utility of urinary NT-proBNP in congenital diaphragmatic hernia: a prospective pilot study

Srirupa Hari Gopal, Kelly Frances Martinek, Candice Vacher, Judith Becker, Nighy P. Varghese, Betul Yilmaz Furtun, Joseph L. Hagan, Sharada H. Gowda, Mohan Pammi, Sridevi Devaraj, Caraciolo J. FernandesBaylor College of Medicine.United States Pediatric ResearchPediatr Res 2024; DOI: 10.1038/s41390-024-03600-x AbstractBackground: Echocardiography is the reference standard for diagnosing pulmonary hypertension (PH) and cardiac dysfunction (CD) in congenital diaphragmatic

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Pharmacoepidemiology of combination pulmonary vasodilator therapy in critically ill infants

Karan R. Kumar, Elizabeth C. Ciociola, Kayla R. Skinner, Gargi M. Dixit, Sunshine Alvarez, Elijah K. Benjamin, Jeffrey C. Faulkner, Rachel G. Greenberg, Reese H. Clark, Daniel K. Benjamin Jr, Christoph P. Hornik, Jan Hau LeeDuke University School of Medicine. University of North Carolina School of Medicine. Pediatrix Center for Research. KK Women’s and Children’s

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Utility of the oxygenation index in management of congenital diaphragmatic hernia: a report from a Thai University Surgical Centre

Issariyaporn Kulngamnetr, Pharuhad Pongmee, Paul D. Losty, Suraida Aeesoa, Ampaipan BoonthaiRamathibodi Hospital and Mahidol University. University of Liverpool. Thailand and United Kingdom Pediatric Surgery InternationalPediatr Surg Int 2024; 40: DOI: 10.1007/s00383-024-05848-0 AbstractBackground: Oxygenation index (OI) is associated with severity of newborn pulmonary hypertension (PH) in congenital diaphragmatic hernia (CDH). Higher OI may indicate worst degree(s) of PH.Objectives: This

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Patterns and Outcomes of Epoprostenol Use in Infants with Congenital Diaphragmatic Hernia Requiring Extracorporeal Life Support

Nikhil R. Shah, Keerthi Burgi, Dimitra M. Lotakis, Mary K. Olive, Amanda D. McCormick, Erin E. Perrone, Joseph T. Church, George B. MychaliskaC.S. Mott Children’s Hospital, Michigan Medicine and University of Michigan Medical School. United States Journal of PediatricsJ Pediatr 2024; DOI: 10.1016/j.jpeds.2024.114286 AbstractObjective: To describe our experience utilizing epoprostenol for pulmonary hypertension (PH) in infants with

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Right-Sided Congenital Diaphragmatic Hernia With Gut Malrotation: A Rare Case Report

Neha Thorbole, Sudhir Malwade, Abhishek Denge, Shivani KaleDr. D.Y. Patil Medical College, Hospital and Research Centre.India CureusCureus 2024; 13: DOI: 10.7759/cureus.65602 AbstractCongenital diaphragmatic hernia (CDH) is a rare surgical cause of respiratory distress in neonates. CDH is caused by the protrusion of the abdominal contents into the thoracic cavity due to the failure of the pleuroperitoneal

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International treatment outcomes of neonates on extracorporeal membrane oxygenation (ECMO) with persistent pulmonary hypertension of the newborn (PPHN): a systematic review

Saad Alhumaid, Abdulrahman A. Alnaim, Mohammed A. Al Ghamdi, Abdulaziz A. Alahmari, Muneera Alabdulqader, Sarah Mahmoud Al Hajji Mohammed, Qasim M. Alalwan, Nourah Al Dossary, Header A. Alghazal, Mohammed H. Al Hassan, Khadeeja Mirza Almaani, Fatimah Hejji Alhassan, Mohammed S. Almuhanna, Aqeel S. Alshakhes, Ahmed Salman Bu Mozah, Ahmed S. Al-Alawi, Fawzi M. Almousa, Hassan

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Morbidity in giant omphaloceles: Predictive factors and management strategies

Laura Martou, Amulya K. SaxenaChelsea Children’s Hospital and Imperial College London.United Kingdom Acta PaediatricaActa Pediatr 2024; DOI: 10.1111/apa.17387 AbstractAim: To identify predictors of morbidity in GO through an analysis of associated anomalies, defect characteristics and management strategies.Methods: PubMed and Ovid EMBASE databases were searched from 2013 to 2023. Primary end points assessed correlation of morbidity with gestational age

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Prenatal Prognosis of Omphalocele Using Magnetic Resonance Imaging Measurement of Fetal Lung Volumes

Simon E. Dadoun, Matthew A. Shanahan, Christian M. Parobek, Brian A. Burnett, Alice King, Pamela Ketwaroo, Roopali V. Donepudi, April D. AdamsTexas Children’s Hospital and Baylor College of Medicine. United States American Journal of Obstetrics and Gynecology Maternal Fetal MedicineAm J Obstet Gynecol MFM 2024; DOI: 10.1016/j.ajogmf.2024.101457 AbstractBackground: Omphalocele is a congenital midline abdominal wall defect resulting

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