Class 3. Pulmonary Hypertension Associated with Lung Hypoplasia

Identification of protein biomarkers associated with congenital diaphragmatic hernia in human amniotic fluid

Sumit Bhutada, Karin Tran-Lundmark, Benjamin Kramer, Peter Conner, Ashley M. Lowry, Eugene Blackstone, Bjorn Frenckner, Carmen Mesas-Burgos, Suneel S. ApteCleveland Clinic. Wallenberg Center for Molecular Medicine and Lund University. Skane University Hospital. Karolinska Institute. United States and Sweden Scientific ResearchSci Res 2023; 13DOI: 10.1038/s41598-023-42576-2 AbstractCongenital diaphragmatic hernia (CDH) is a severe birth defect frequently associated with […]

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Pulmonary outcomes of congenital diaphragmatic hernia patients based on defect size (CDH Study Group Stage)

Hina Emanuel, Hannah V. Breitschopf, Matthew T. Harting, Diana J. Martinez Castillo, Aravind Yadav, Katrina McBeth, S. Syed Hashmi, Ashley H. Ebanks, Tomika S. Harris, Kevin P. Lally, Cindy K. Jon, James M. Stark, Ricardo A. MosqueraMcGovern Medical School at the University of Texas Health Science Center and Children’s Memorial Hermann Hospital.United States Translational PediatricsTransl

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Pathological findings in congenital diaphragmatic hernia on necropsy studies: A single-center case series

Chu-Yi Meng, Ji-Zhen Zou, Ying Wang, Yan-Dong Wei, Jing-Na Li, Chao Liu, Zhong Feng, Ling-Ling Cai, Ping Xiao, Li-Shang MaChildren’s Hospital of Capital Institute of Pediatrics and Graduate School of Peking Union Medical College.China Pediatric PulmonologyPediatr Pulmonol 2023; 58: 2628-2636DOI: 10.1002/ppul.26565 AbstractIntroduction: Congenital diaphragmatic hernia (CDH) is associated with high mortality rates and significant pulmonary morbidities. The

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Think out of the box: association of left congenital diaphragmatic hernia and abnormal origin of the right pulmonary artery : A train can hide another

Arthur Gavotto, Pascal Amedro, Gilles CambonieArnaud de Villeneuve Hospital and Montpellier University Hospital. Bordeaux University Hospital and Bordeaux University.France BioMed Central PediatricsBMC Pediatr 2023; 23: DOI: 10.1186/s12887-023-04164-1 AbstractBackground: We report the occurrence of a severe pulmonary hypertension (PH) in a neonate affected by a left congenital diaphragmatic hernia (CDH). PH in this patient was associated with an

Think out of the box: association of left congenital diaphragmatic hernia and abnormal origin of the right pulmonary artery : A train can hide another Read More »

Hemolysis during Venovenous ECMO in Neonates with Congenital Diaphragmatic Hernia: A Prospective Observational Study

Lotte Lemloh, Bartolomeo Bo, Hannah Ploeger, Ramona Dolscheid-Pommerich, Andreas Mueller, Florian KipfmuellerChildren’s Hospital, University Hospital Bonn and University of Bonn. Germany Journal of PediatricsJ Pediatr 2023; DOI: 10.1016/j.jpeds.2023.113713 AbstractObjective: To investigate the incidence of hemolysis and its association with outcome in neonates with congenital diaphragmatic hernia (CDH) requiring venovenous extracorporeal membrane oxygenation (ECMO) treatment using a Medos

Hemolysis during Venovenous ECMO in Neonates with Congenital Diaphragmatic Hernia: A Prospective Observational Study Read More »

Prenatal MRI assessment of mediastinal shift angle as a feasible and effective risk stratification tool in isolated right-sided congenital diaphragmatic hernia

Wen Ding, Yuanyuan Gu, Kaiyu Wang, Huiying Wu, Xiachun Zhang, Rui Zhang, Hongying Wang, Li Huang, Junjian Lv, Bo Xia, Wei Zhong, Qiuming He, Longlong HouGuangzhou Women and Children’s Medical Center and Guangzhou Medical University. China European RadiologyEur Radiol 2023; DOI: 10.1007/s00330-023-10178-1 AbstractObjectives: To develop a mediastinal shift angle (MSA) measurement method applicable to right-sided congenital diaphragmatic

Prenatal MRI assessment of mediastinal shift angle as a feasible and effective risk stratification tool in isolated right-sided congenital diaphragmatic hernia Read More »

Sex-Specific Differences in Congenital Diaphragmatic Hernia Mortality

Shelby R. Sferra, Matthew Guo, Andres J. Gonzalez-Salazar, Annalise B. Penikis, Abigail J. Engwall-Gill, Ashley Ebanks, Matthew T. Harting, Joseph M. Collaco, Shaun M. Kunisaki, CDH Study GroupJohns Hopkins University School of Medicine. University of Texas McGovern Medical School and Children’s Memorial Hermann Hospital. United States Journal of PediatricsJ Pediatr 2023; 259DOI: 10.1016/j.jpeds.2023.113481 AbstractObjective: To compare disease

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Quantitative Measures of Right Ventricular Size and Function by Echocardiogram Correlate with Cardiac Catheterization Hemodynamics in Congenital Diaphragmatic Hernia

Catherine M. Avitabile, Sabrina Flohr, Leny Mathew, Yan Wang, Devon Ash, David B. Frank, Jennifer E. Tingo, Natalie E. Rintoul, Holly L. HedrickUniversity of Pennsylvania Perelman School of Medicine and Children’s Hospital of Philadelphia. United States Journal of PediatricsJ Pediatr 2023; 261DOI: 10.1016/j.jpeds.2023.113564 AbstractObjective: To evaluate associations between cardiac catheterization (cath) hemodynamics, quantitative measures of right ventricular

Quantitative Measures of Right Ventricular Size and Function by Echocardiogram Correlate with Cardiac Catheterization Hemodynamics in Congenital Diaphragmatic Hernia Read More »

Single-cell transcriptomic profiling of microvascular endothelial cell heterogeneity in congenital diaphragmatic hernia

Jason O. Robertson, Peter Bazeley, Serpil C. Erzurum, Kewal AsosinghCleveland Clinic.United States Scientific ReportsSci Rep 2023; 13DOI: 10.1038/s41598-023-37050-y AbstractCongenital diaphragmatic hernia (CDH) is a neonatal anomaly that includes pulmonary hypoplasia and hypertension. We hypothesized that microvascular endothelial cell (EC) heterogeneity is different in CDH lungs and related to lung underdevelopment and remodeling. To test this, we

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Dynamics of pulmonary hypertension severity in the first 48 h in neonates with prenatally diagnosed congenital diaphragmatic hernia

Judith Leyens, Lukas Schroeder, Annegret Geipel, Christoph Berg, Bartolomeo Bo, Lotte Lemloh, Neil Patel, Andreas Mueller, Florian KipfmuellerChildren’s Hospital, University of Bonn.  Royal Hospital for Children.Germany and United Kingdom Frontiers in PediatricsFront Pediatr 2023; 11DOI: 10.3389/fped.2023.1164473 AbstractIntroduction: Pulmonary hypertension (PH) is one of the major contributing factors to the high morbidity and mortality in neonates with congenital

Dynamics of pulmonary hypertension severity in the first 48 h in neonates with prenatally diagnosed congenital diaphragmatic hernia Read More »

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