Class 1. Persistent Pulmonary Hypertension of the Newborn

Two case reports of idiopathic prenatal closure of the ductus arteriosus complicated at birth by severe pulmonary hypertension successfully treated without intubation

Leonce Mwizerwa, Raphael Joye, Vladimir L. Cousin, Iliona Malaspinas, Maya Bouhabib, Hugues Lucron, Maurice Beghetti, Julie WackerGeneva University Hospitals and University of Geneva. AP-HP Paris-Saclay University and Bicêtre Hospital.Switzerland and France Translational PediatricsTrans Pediatr 2025; 14: 2374-2380DOI: 10.21037/tp-2025-264 AbstractBackground: Prenatal closure of the ductus arteriosus (DA) is an uncommon but potentially severe condition that can result in […]

Two case reports of idiopathic prenatal closure of the ductus arteriosus complicated at birth by severe pulmonary hypertension successfully treated without intubation Read More »

Outcomes in early term neonates requiring extracorporeal membrane oxygenation

Sourabh Verma, Bryn H. S. Seltzer, Jason C. Fisher, Erin CicaleseHassenfeld Children’s Hospital at New York University Langone.United States Journal of Perinatal MedicineJ Perinat Med 2025; DOI: 10.1515/jpm-2025-0235 AbstractObjectives: To evaluate ECMO-related morbidity and mortality between Early-term (ET) and Full-term (FT) infants.Methods: We performed a retrospective review of 3,831 neonatal ECMO runs for meconium aspiration syndrome (MAS) and/or

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Mobile ECMO for inter-hospital transport of pediatric patients: experience from 22 cases

Yufan Yang, Xiangni Wang, Xiulan Lu, Xinping Zhang, Jiaotian Huang, Zhenghui XiaoUniversity of South China and Hunan Children’s Hospital. Affiliated Children’s Hospital of Xiangya School of Medicine and Central South University. Hunan Traditional Chinese Medical College. Frontiers in PediatricsFront Pediatr 2025; 13: DOI: 10.3389/fped.2025.1664454 AbstractObjective: To summarize the management experience of inter-hospital transport of critically ill children

Mobile ECMO for inter-hospital transport of pediatric patients: experience from 22 cases Read More »

Vardenafil vs. Sildenafil for the Treatment of Persistent Pulmonary Hypertension in Newborns

Sania El-HindiChildren’s Hospital.Syria Indian Journal of PediatricsIndian L Pediatr 2025; DOI: 10.1007/s12098-025-05787-1 AbstractAbstract Not Available CategoryClass I. Persistent Pulmonary Hypertension of the NewbornMedical Therapy. Efficacy or Lack of Efficacy Age Focus: Pediatric Pulmonary Vascular Disease Fresh or Filed Publication: Fresh (PHresh). Less than 1-2 years since publication Article Access Free PDF File or Full Text Article

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Neonatal early-onset sepsis caused by Streptococcus Gallolyticus subsp. Pasteurianus with severe pulmonary hypertension and leukemoid reaction: a case report

Xuelian Wang, Ling Wang, Yuan Yuan, Xiaopeng Zhao, Huayan ZhangGuangzhou Women and Children’s Medical Center and Guangzhou Medical University. Children’s Hospital of Philadelphia.China and United States BioMedical Central PediatricsBMC Pediatr 2025; 25: DOI: 10.1186/s12887-025-06026-4 AbstractBackground: Streptococcus gallolyticus subsp. pasteurianus (SGSP) is an uncommon cause of neonatal early-onset sepsis (EOS). We present a case of neonatal EOS attributed

Neonatal early-onset sepsis caused by Streptococcus Gallolyticus subsp. Pasteurianus with severe pulmonary hypertension and leukemoid reaction: a case report Read More »

Neonatal pulmonary hypertension in the NICU: a 10-year single-center experience

Oguzhan Ay, Sezgin Gunes, Erkan Erfidan, Ayse SimsekIzmir Democracy University and Buca Seyfi Demirsoy Teaching and Research Hospital. Izmir City Hospital. Istanbul Aydin University and VM Medical Park Florya Hospital Istanbul. Turkey BioMedical Central PediatricsBMC Pediatr 2025; 25: DOI: 10.1186/s12887-025-05928-7 AbstractBackround Neonatal pulmonary hypertension (PHT) is a significant cause of morbidity and mortality in newborns. Early

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Clinical Profile and Morbidity Patterns in Neonates Born Through Meconium-Stained Amniotic Fluid Based on a Prospective Observational Study From a Rural Tertiary Care Center in India

Gaurav Dutta, Suresh Kumar Yadav, Ekansh Rathoria, Rohitash Lahari, Akash Srivastava, Richa RathoriaHind Institute of Medical Sciences.India CureusCureus 2025; 17: DOI: 10.7759/cureus.90332 AbstractBackground: Meconium observed in the amniotic fluid during delivery may warrant clinical monitoring due to potential neonatal complications. This study aimed to assess the incidence, risk factors, and outcomes associated with meconium aspiration syndrome

Clinical Profile and Morbidity Patterns in Neonates Born Through Meconium-Stained Amniotic Fluid Based on a Prospective Observational Study From a Rural Tertiary Care Center in India Read More »

Trends, Burden, and Inequality in Neonatal Pulmonary Arterial Hypertension: Global Estimates From 1990 to 2021

Xinbao Wang, Zhe Tang, Ziwei WangBeijing Friendship Hospital and Capital Medical University.China Pediatric PulmonologyPediatr Pulmonol 2025; 60: DOI: 10.1002/ppul.71277 AbstractBackground: Pulmonary arterial hypertension (PAH) is a rare but life-threatening disorder in neonates, characterized by increased pulmonary vascular resistance and right heart failure. Despite advances in neonatal intensive care, the global burden of neonatal PAH remains poorly defined,

Trends, Burden, and Inequality in Neonatal Pulmonary Arterial Hypertension: Global Estimates From 1990 to 2021 Read More »

Nebulized nitroglycerin as an adjuvant drug in management of persistent pulmonary hypertension of newborns: a randomized controlled trial

Marwa Mohammed Farag, Hesham Abd El‑Rahim Ghazal, Aly Mohamed Abdel‑Mohsen, Moataz Ahmed RezkAlexandria University Hospital, Alexandria. Egypt European Journal of PediatricsEur J Pediatr 2025; 184: DOI: 10.1007/s00431-025-06381-5 AbstractThe objective was to evaluate the effect of nebulized nitroglycerin (NNG) in neonates with persistent pulmonary hypertension (PPHN). The study focused on assessing changes in echocardiographic and clinical parameters

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Risk Factors and Predictors of Mechanical Ventilation in Neonates With Meconium Aspiration Syndrome: A Retrospective Study at King Salman Armed Forces Hospital, Tabuk, Saudi Arabia

Abdulaziz A. Bedaiwi, Muhanned Amawi, Wegdan MawlanaKing Salman Armed Forces Hospital.Saudi Arabia CureusCureus 2025; 17: DOI: 10.7759/cureus.88486 AbstractBackground: Meconium aspiration syndrome (MAS) is a critical neonatal condition predominantly associated with term and post-term pregnancies, characterized by the aspiration of meconium-stained amniotic fluid (MSAF) leading to severe respiratory distress. Despite advances in obstetric and neonatal care, MAS

Risk Factors and Predictors of Mechanical Ventilation in Neonates With Meconium Aspiration Syndrome: A Retrospective Study at King Salman Armed Forces Hospital, Tabuk, Saudi Arabia Read More »

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