Class 1. Persistent Pulmonary Hypertension of the Newborn

Persistent Pulmonary Hypertension of the Newborn: A Practical Review for UK Level 2 Local Neonatal Units

Elnazeer MohamedEast Surrey Hospital.United Kingdom CureusCureus 2026; 18: DOI: 10.7759/cureus.116003 AbstractIn persistent pulmonary hypertension of the newborn (PPHN), pulmonary vascular resistance fails to fall after birth, resulting in right-to-left shunting and hypoxemia out of proportion to the underlying lung disease. Inhaled nitric oxide (iNO) is generally provided by tertiary neonatal intensive care units and neonatal

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Haemodynamic and neurophysiological assessments for 2-year outcome prediction in neonates with hypoxic-ischaemic encephalopathy treated with therapeutic hypothermia: a systematic review and meta-analysis

Mona Noureldein, Vincent So, Lamia M. Hayawi, Ayman Saker, Laurent Renesme, Anne Tsampalieros, Nadya Ben FadelUniversity Hospitals Birmingham NHS Foundation Trust. Children’s Hospital of Eastern Ontario and University of Ottawa.United Kingdom and Canada British Medical Journals Paediatrics OpenBMJ Paediatr Open 2026; 10: DOI: 10.1136/bmjpo-2026-004810 AbstractObjective: To evaluate the prognostic accuracy of amplitude-integrated electroencephalography (aEEG), cerebral

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High-Frequency Oscillatory Ventilation Combined With Inhaled Nitric Oxide for Persistent Pulmonary Hypertension of the Newborn: A Single-Center Randomized Clinical Trial

Yanbo Wang, Qian Wu, Xin Zhang, Zhongyi Sun, Mingming Zhang, Xiao Liu, Bin ZhouXuzhou Central Hospital.China Canadian Respiratory JournalCan Respir J 2026; DOI: 10.1155/carj/8717590 AbstractBackground: Persistent pulmonary hypertension of the newborn (PPHN) may respond incompletely to inhaled nitric oxide (iNO) when poorly recruited lung limits delivery to ventilated alveoli. We evaluated whether high-frequency oscillatory ventilation

High-Frequency Oscillatory Ventilation Combined With Inhaled Nitric Oxide for Persistent Pulmonary Hypertension of the Newborn: A Single-Center Randomized Clinical Trial Read More »

Effect of Birth Asphyxia on Neonatal Heart: A Two-dimensional Echocardiography-based Study at a Tertiary Care Center

Vikas N. Solunke, Monika S. Reddy, Shivprasad MundadaVilasrao Deshmukh Government Medical College,India Heart ViewsHeart Views 2026; 27: DOI: 10.4103/heartviews.heartviews_74_25 AbstractBackground: Perinatal asphyxia is a significant cause of neonatal morbidity and mortality, with potential long-term complications. Timely identification and management are crucial to improving neonatal outcomes. This study aims to assess the maternal and neonatal outcomes

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An infant with persistent pulmonary hypertension of the newborn and congenital hypothyroidism

Georgia Eva Fouli, Raghavendra Subba-Rao, Ravindra Bhat, Anne GreenoughKing’s College Hospital. United Kingdom Case Reports in Perinatal MedicineCase Rep Perinat Med 2026; DOI: 10.1515/crpm-2026-0003 AbstractObjectives: We report an infant who presented with persistent pulmonary hypertension of the newborn (PPHN) to highlight this was likely due to congenital hypothyroidism.Case presentation: A male infant born at term presented with respiratory

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Artificial intelligence in neonatal hemodynamics: toward earlier and more reliable detection of pulmonary hypertension

Gabriel Altit, Guilherme Sant’AnnaMontreal Children’s Hospital and McGill University.Canada Pediatric ResearchPediatr Res 2026; DOI: 10.1038/s41390-026-05461-y AbstractAbstract Not Available CategoryClass I. Persistent Pulmonary Hypertension of the NewbornClass III. Pulmonary Hypertension Associated with Lung DiseaseAssessment of Pulmonary Vascular Disease and Therapy Through Learning Methods and Artificial Intelligence Age Focus: Pediatric Pulmonary Vascular Disease Fresh or Filed Publication: Fresh

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Managing Neonatal Pulmonary Hypertension in Low-Resource Settings

R. Kishore Kumar, Ju-Lee Oei, Rajeshwari Madappa, Satyan LakshminrusimhaCloudnine Hospital, Bangalore. Notre Dame University. University of Queensland. Mater Mother’s Hospital. Sigma Hospital, Mysuru. UC Davis Children’s Hospital and UC Davis School of Medicine.India, Australia and United States Journal of Paediatrics and Child HealthJ Paediatr Child Health 2026; DOI: 10.1111/jpc.70550 AbstractPersistent pulmonary hypertension of the newborn (PPHN)

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Postoperative Pulmonary Hypertension after Primary Abdominal Wall Closure for Small Omphalocele: A Case Series

Seitaro Kosaka, Takanori Ochi, Shuko Nojiri, Tadaharu Okazaki, Go MiyanoJuntendo University School of Medicine and Juntendo University Urayasu Hospital.Japan European Journal of Pediatric Surgery ReportsEur J Pediatr Surg Rep 2026; 14: e45-e49DOI: 10.1055/a-2937-1779 AbstractPrimary closure is a low-risk option for small omphaloceles (SOs). However, despite the absence of liver herniation and limited volume of herniated viscera,

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Impact of the neonatal intensive critical ultrasound workflow for managing neonatal acute pulmonary hypertension

Mingsheng Zheng, Wenwei Ling, Jingyi Zhang, Rong Ju, Tiantian Xiao, Yiyong Fu, Biao Li, Yi Zheng, Jun Wang, Xiaofeng Zhou, Gaoyang Qin, Lingping Zhong, Ling Zhu, Youning Hu, Xiaolong Zhang, Zhengwei Ye, Huaying Li, Yang Liu, Nana Wu, Shuqiang Gao, Xuhong Hu, Yan Jiang, Xiaohong LuoChengdu Women’s and Children’s Central Hospital, School of Medicine and

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Vardenafil efficacy for the treatment of persistent pulmonary hypertension of the newborn

Sania El-HindiChildren’s Hospital of Damascus University.Syria World Journal of Clinical PediatricsWorld J Clin Pediatr 2026; 15: DOI: 10.5409/wjcp.118862 AbstractBackground: Persistent pulmonary hypertension of the newborn (PPHN) remains a challenging condition with high morbidity and mortality despite advancements in management, which implies the need to investigate new therapies. While sildenafil is the drug of choice in resource-limited centers

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