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The NLRP3 Inflammasome Increases Pulmonary Vascular Remodeling in Experimental Pulmonary Arterial Hypertension

Emmanouil Mavrogiannis, Rebeca Weldeghebreal, Iris R. Schilthuis, Zain K. Fal, Niels J. Kloosterhuis, Mirjam H. Koster, Wim Timens, Johannes M. Douwes, Rolf M. F. Berger, Marit WesterterpBeatrix Children’s Hospital, University Medical Center Groningen and University of Groningen. Netherlands Pulmonary CirculationPulm Circ 2026; 16: DOI: 10.1002/pul2.70354 AbstractPulmonary arterial hypertension (PAH) is a progressive vasculopathy leading to right-sided […]

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Iron Homeostasis at High Altitude in Patients With Pulmonary Hypertension

Aurelia E. Reiser, Markus Thiersch, Max Gassmann, Simon R. Schneider, Laura Mayer, Stéphanie Saxer, Michael Furian, Richard Sparla, Esther I. Schwarz, Mona Lichtblau, Martina U. Muckenthaler, Silvia UlrichUniversity of Zürich and University Hospital of Zurich. Eastern Switzerland University of Applied Sciences. University of Heidelberg. Switzerland and Germany Pulmonary CirculationPulm Circ 2026; 16: DOI: 10.1002/pul2.70352 AbstractIron deficiency

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The Role of Piezo Ion Channels in Pulmonary Hypertension

Kewei Chen, Lingchen Li, Yajie Huang, Lixia Ye, Yu Wang, Ziming Zhang, Chengcheng Hang, Qiqi Li, Qianyun Cao, Lizhong DuChildren’s Hospital, Zhejiang University School of Medicine and National Clinical Research Center for Children and Adolescents’ Health and Diseases. Second Affiliated Hospital and School of Medicine of Zhejiang University. China Pulmonary CirculationPulm Circ 2026; 16: DOI: 10.1002/pul2.70360

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Long-Term Postoperative Outcomes of Sinus Venosus Defect

Mariama Touray, Magalie Ladouceur, Judith Bouchardy, Markus Schwerzmann, Matthias Greutmann, Daniel Tobler, Reto Engel, Harald Gabriel, Caroline Blanche, Etienne Pruvot, Nicole Sekarski, Tobias RutzLausanne University Hospital, University of Lausanne. Hôpital Européen Georges Pompidou, Hôpitaux de Paris and Paris-Saclay University. University Hospitals of Geneva. University of Bern. University of Zurich. University Hospital of Basel and University

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Cardiac Remodeling Patterns in Pediatric and Adolescent Patients with Sickle Cell Disease and Their Association with the Genotype and Clinical Severity of the Disease: A Systematic Review

Alam Eldin M. Mustafa, Niemat Mohammed Tahir AliKing Khalid University. University of Kordofan.Saudi Arabia and Sudan HealthcareHealthcare 2026; 14:DOI: 10.3390/healthcare14142180 AbstractBackground: Sickle cell disease (SCD) is the most common inherited blood disorder globally, affecting approximately 300,000 newborns annually. Cardiac remodeling, resulting from chronic anemia, vascular obstruction, and endothelial dysfunction, substantially contributes to morbidity and mortality in patients

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Performance of the Occlutech® Atrial Flow Regulator Device in Patients With Either Failing Fontan Circulations or Irreversible Pulmonary Hypertension

Mehmet Kucuk, Jenny E. Zablah, Gregory Fleming, Dennis Vanloozen, Oliver Aregullin, Konstantin Averin, Mark H. Hoyer, Mark A. Law, James A. Kuo, Ryan Leahy, Christopher Iskander, Gareth J. MorganChildren’s Hospital Colorado. Duke University Medical Center. Cook Children’s Medical Center. Spectrum Health Helen DeVos Children’s Hospital. Cohen Children’s Medical Center. Riley Hospital for Children and Indiana

Performance of the Occlutech® Atrial Flow Regulator Device in Patients With Either Failing Fontan Circulations or Irreversible Pulmonary Hypertension Read More »

Misdiagnosed as Idiopathic PAH: Methylmalonic Acidemia as a Reversible Cause of Pediatric Pulmonary Hypertension

Yan Wu, Yuan-Rui Deng, Xiao-Pei Cui, Sheng-Song Zhu, Jiang Shan Tan, Song Hu, Lu HuaFuwai Hospital, Fuwai Shenzhen Hospital and Peking Union Medical College. Qilu Hospital of Shandong University. China Journal of Heart and Lung TransplantationJ Heart Lung Transplant 2026; DOI: 10.1016/j.healun.2026.07.021 AbstractBackground: Methylmalonic acidemia (MMA)-induced pulmonary hypertension (PH) is a rare but treatable cause of pediatric

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Variability in the Diagnostic Criteria for Severe Pertussis: A Systematic Review

Pauline Labe, Alexandre Meunier. Pauline Leroux, Mirko Sadi, Carla Rodrigues, Valerie Bouchez, Marion Grimaud, Sylvain Brisse, Jérémie F. Cohen, Julie ToubianaUniversité Paris Cité, Institut Pasteur and Hôpital Necker-Enfants Malades. France Journal of the American Medical Association Network OpenJAMA Netw Open 2026; 9:DOI: 10.1001/jamanetworkopen.2026.22211 AbstractImportance: Pertussis, or whooping cough, can be life threatening in infants, yet the concept

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Multimodal imaging of infantile scimitar syndrome with Eisenmenger physiology: A case report of complex intracardiac and extracardiac shunts

Berihu Gebre, Yirgalem Gereziher, Catherine Alcober, Gladys Baltazar, Viachaslau MarkauNauru Medical Center. Mekelle University.Republic of Nauru and Ethiopia Radiology Case ReportsRadiol Case Rep 2026; 21: 4642-4650DOI: 10.1016/j.radcr.2026.06.141 AbstractScimitar syndrome is a rare congenital vascular malformation in which the right pulmonary veins drain abnormally into the inferior vena cava, right atrium, or portal vein instead of the

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Meta-analysis of prostacyclin therapy for persistent pulmonary hypertension with congenital diaphragmatic hernia

Shouliang Jiang, Xue Han, Yang He, Qian Gao, Juan Liang, Tingting Zhu, Li Zhang, Jun TangWest China Second University Hospital and Sichuan University. China Journal of Pediatric SurgeryJ Pediatr Surg 2026; DOI: 10.1016/j.jpedsurg.2026.163301 AbstractObjective: To evaluate the efficacy and safety of prostacyclin in the treatment of persistent pulmonary hypertension in congenital diaphragmatic hernia.Methods: A systematic literature search was

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