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Reversing the irreversible? A case of successful surgical repair in a late-presenting aortopulmonary window with severe pulmonary hypertension

Rido Mulawarman, Ericko Ongko Joyo, Muhamad Adrin Aefiansyah Putra, Aditya Agita Sembiring, Sisca Natalia Siagian, Oktavia LilyasarUniversitas Indonesia. Indonesia Egyptian Heart JournalEgypt Heart J 2026; 78: DOI: 10.1186/s43044-026-00726-7 AbstractBackground: Aortopulmonary window (APW) is a rare congenital heart defect, accounting for only 0.2-0.6% of all congenital cardiac anomalies, and is usually identified and surgically corrected within the first […]

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Alternative Polyadenylation Signatures Distinguish Maladaptive Right Ventricular Remodeling in Pulmonary Hypertension: Implications for RNA-Based Diagnostics and Therapeutics

Janani Subramaniam, Venkata Jonnakuti, Scott D. Collum, Sandra Martineau, Kai-Lieh Huang, Sandra Breuils-Bonnet, Andrea L. Frump, Bindu H. Akkanti, Jayeshkumar A. Patel, Manish K. Patel, Ismael Salas de Armas, Isabella N. Lefebvre, Rajko Radovancevic, Elvin Blanco, Eric J. Wagner, Igor Gregoric, Sriram Nathan, Biswajit Kar, Steeve Provencher, Sebastien Bonnet, François Potus, Hari Krishna Yalamanchili, Harry

Alternative Polyadenylation Signatures Distinguish Maladaptive Right Ventricular Remodeling in Pulmonary Hypertension: Implications for RNA-Based Diagnostics and Therapeutics Read More »

Case Report: A pediatric case of chronic active Epstein-Barr virus infection complicated by pulmonary arterial hypertension

Meng Zhang, Kai Wang, Xinyi Xu, Wei Ji, Tingliang Liu, Wei Gao, Ying GuoShanghai Children’s Medical Center, School of Medicine, Shanghai Jiao Tong University.China Frontiers in Cardiovascular MedicineFront Cardiovasc Med 2026; 13: DOI: 10.3389/fcvm.2026.1724841 AbstractObjective: To enhance clinicians’ awareness of pulmonary arterial hypertension (PAH) complicating chronic active Epstein-Barr virus infection (CAEBV) in pediatric patients.Method: Clinical data of a

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Macitentan vs Standard of Care in Pediatric Pulmonary Arterial Hypertension (TOMORROW): A Randomized Clinical Trial

Rolf M. F. Berger, D. Dunbar Ivy, Julian I. Borissoff, Sofija Cerovic, Dénes Csonka, Tatiana Remenová, Dominik Richard, Matthieu Villeneuve, Maurice BeghettiBeatrix Children’s Hospital, University Medical Center Groningen and University of Groningen. Children’s Hospital Colorado. Johnson & Johnson. University Hospitals of Geneva.Netherlands, United States and Switzerland Journal of PediatricsJ Pediatr 2026; DOI: 10.1016/j.jpeds.2026.115057 AbstractObjectives: To evaluate pharmacokinetics

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Incidental pulmonary arteriovenous malformation

Mallory A. Von Lotten, Eric Howell, J. Andrew WatsonUniversity of Alabama at Birmingham Heersink School of Medicine. United States Journal of Hospital MedicineJ Hosp Med 2026; DOI: 10.1002/jhm.70259 AbstractAbstract Not Available CategoryPulmonary Arteriovenous Malformations Age Focus: Pediatric Pulmonary Vascular Disease Fresh or Filed Publication: Fresh (PHresh). Less than 1-2 years since publication Article Access Free PDF

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Hypercapnia as a Key Mechanism in the Development of Pulmonary Hypertension in Malignant Pertussis: A Case Report

Juan Ignacio Muñoz-Bonet, Francisco José Sebastián-Cuevas, Eva María Flor-Macián, María del Carmen Ortega-Sánchez, Andrés Rodríguez-Sacristán, Juan BrinesHospital Clínico Universitario. University of Valencia. Hospital Dr. Peset Valencia. Hospital Universitario Virgen Macarena.Spain Respirology Case ReportsRespirol Case Rep 2026; 14: DOI: 10.1002/rcr2.70528 AbstractMalignant pertussis (MP) is a highly lethal complication of pertussis in young infants, typically associated with hyperleukocytosis, pulmonary

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A circulating MicroRNA signature for the diagnosis of pulmonary arterial hypertension and functional characterization of candidate miR-3168

Mauro Lago-Docampo, Ainhoa Iglesias-López, Carlos Vilariño, Adolfo Baloira, Joan Albert Barberá, Isabel Blanco, Diana ValverdeUniversidade de Vigo. Galicia Sur Health Research Institute. Hospital Povisa. Complejo Hospitalario Universitario de Pontevedra. University of Barcelona. Stanford University School of Medicine.Spain and United States Scientific ReportsSci Rep 2026; DOI: 10.1038/s41598-026-42550-8 AbstractPulmonary Arterial Hypertension (PAH) is a rare, progressive disorder characterized

A circulating MicroRNA signature for the diagnosis of pulmonary arterial hypertension and functional characterization of candidate miR-3168 Read More »

Mechanical Compression Causes Lung Hypoplasia in Congenital Diaphragmatic Hernia with GATA4 Genetic Variants

Betty Pham, Zhuowei Li, Gidsela Luna, Nicole Talaba, Na Zhang, Giangela M. Stokes, Mark D. Wienjold, Jinhao Xu, Yujuan Su, Rebecca Hernan, Wendy K. Chung, Xin Sun, David J. McCulleyUniversity of California, San Diego and Rady Children’s Hospital. University of Wisconsin-Madison. Boston Children’s Hospital and Harvard Medical School. United States American Journal of Physiology Lung

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The Pulmonary Hypertension Global Patient Survey: Understanding the Invisible Burden of Paediatric Pulmonary Hypertension

Sadia Quyam, Sarah Drumm, Shiv Mungala, Katherine Bunclark, Gerald Fischer, Eva Otter, Hakim Ghani, Wendy Gin‐Sing, Luke Howard, Marcin Kurzyna, Pisana Ferrari, Lynsay Macdonald, Joseph Newman, Millicent Stone, Mark Toshner, Joanna Pepke Zaba, Maurice Beghetti, Shahin MoledinaGreat Ormond Street Hospital for Children and University College London. Pulmonary Vascular Research Institute. Royal Statistical Society. University of

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Obstructive Sleep Apnea-Hypopnea Syndrome in Children With Down Syndrome Treated at a Tertiary Care Hospital in Northeastern Colombia

Silvia N. Suarez Mantilla, Victor Manuel Mora Bautista, Martha Lucia Africano Leon, Diana C. Vergara Arenas, Yuli E. Rojas, Sergio Serrano-GomezUniversidad Industrial de Santander. Clinica Materno Infantil San Luis. Columbia CureusCureus 2026; 18: DOI: 10.7759/cureus.102624 AbstractObstructive sleep apnea-hypopnea syndrome (OSAHS) is frequent in children with Down Syndrome (DS), associated with anatomical characteristics such as midfacial hypoplasia,

Obstructive Sleep Apnea-Hypopnea Syndrome in Children With Down Syndrome Treated at a Tertiary Care Hospital in Northeastern Colombia Read More »

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