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Neurological manifestations and vasculopathy in PLCG2-associated antibody deficiency and immune dysregulation (APLAID): a case series

Kosar Asna Ashari, Rebecca MacRae, David P. Hoytema van Konijnenburg, Craig D. Platt, Maryam Ashoor, Alfred P. See, Agnieszka Kielian, Amy Danehy, Riten Kumar, Elliot James, Kristin Houghton, Sheri Harder, Mark P. Gorman, Stacy A. Kahn, Ankana Daga, Sadaf H. Hussain, Alicia M. Johnston, Alicia Casey, Jodie D. Ouahed, Wai Wong, Kathy Jenkins, Susan Prockop,

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Prenatal Diagnosis of Pulmonary Arteriovenous Malformation With 3D/4D STIC Fetal Echocardiography

Amit Kumar Pandey, Balu VaidyanathanAmrita Institute of Medical Sciences.India Journal of Clinical UltrasoundJ Clin Ultrasound 2026; DOI: 10.1002/jcu.70404 AbstractPulmonary arteriovenous malformation (PAVM) is a rare congenital vascular anomaly characterized by direct communication between the pulmonary artery and vein, resulting in a right-to-left shunt. Prenatal diagnosis remains uncommon. We report a fetal PAVM diagnosed at 21

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High-Altitude Pulmonary Edema in Children in Mexico City: A Case Series

Alejandro Ferreiro Marin. María Paula Ferreiro Soria, Karla Sánchz Olivera, Aranza Suárez Ortega, Luis Martin Garrido GarcíaCentro Médico ABC. Universidad Anáhuac México.Mexico High Altitude Medicine and BiologyHigh Alt Med Biol 2026; DOI: 10.1177/15578682261500306 AbstractHigh-altitude pulmonary edema (HAPE) is a potentially life-threatening form of noncardiogenic pulmonary edema caused by hypobaric hypoxia. Although well characterized in adults,

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In Vitro Models to Study Fibroelastic Remodeling of the Endocardium in Congenital Heart Disease

Julia Gaal, Cindy Zajac, Sophie C. Doettl, Magnus von Piechowski, Kerstin Saraci, Viktoria Weixler, Daniel Diaz-Gil, Pedro J. del Nido, Ingeborg FriehsBoston Children’s Hospital. Charité University. University Hospital of Giessen and Marburg and Justus Liebig University Giessen. Harvard Medical School. United States and Germany Pediatric CardiologyPediatr Cardiol 2026; DOI: 10.1007/s00246-026-04503-w AbstractCongenital heart defects (CHD) are

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Right Ventricular Shear Wave Velocity Throughout the Cardiac Cycle in Pediatric Pulmonary Hypertension

Maelys Venet, Aimen Malik, Pierre Gravinay, Sarah Pradhan, Andreea Dragulescu, Luc Mertens, Jérôme Baranger, Olivier VillemainHospital for Sick Children. Institut Hospitalo-Universitaire (IHU) Liryc and Fondation Bordeaux Université. Centre Hospitalier Universitaire (CHU) de Bordeaux. PSL Research University.Canada and France European Heart Journal Cardiovascular ImagingEur Heart J Cardiovasc ImagingDOI: 10.1093/ehjci/jeag291 AbstractAbstract Not Available CategoryDiagnostic Testing for Pulmonary

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Use of sotatercept in an adolescent patient with idiopathic pulmonary arterial hypertension

Kohei Kurosaki, Yohei Akazawa, Tomoyasu Yuki, Kohta Takei, Kiyohiro TakigikuNagano Children’s Hospital. Japan Journal of Cardiology CasesJ Cardiol Cases 2026; 34: 173-176DOI: 10.1016/j.jccase.2026.06.010 AbstractAn adolescent boy with idiopathic pulmonary arterial hypertension (iPAH) presented with persistent pulmonary hypertension with right ventricular dysfunction despite upfront oral triple combination therapy. Additional sotatercept treatment led to a striking improvement

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Neonatal and 18-24-Month Growth and Neurodevelopmental Outcomes in Very Low Birth Weight Infants With Severe Congenital Heart Disease: A Korean Neonatal Network Study

Jung Il Kwak, Soo Hyun Kim, Kyusang Yoo, Tae-Gyeong Kim, Juhee Park, Abraham Kwak, Joo Hyung Roh, Jeong Min Lee, Ha Na Lee, Jiyoon Jeong, Chae Young Kim, Euiseok Jung, Byong Sop LeeAsan Medical Center Children’s Hospital and University of Ulsan College of Medicine.Republic of Korea Korean Circulation JournalKorean Circ J 2026; DOI: 10.4070/kcj.2026.0106 AbstractBackground

Neonatal and 18-24-Month Growth and Neurodevelopmental Outcomes in Very Low Birth Weight Infants With Severe Congenital Heart Disease: A Korean Neonatal Network Study Read More »

Development of a Novel Nanoparticle Targeting Endothelial Cells from Patients with Pulmonary Arterial Hypertension

Gabriel Floarea, Nasser Assi, Maytham Ismail, Anderson Gattis, Tadanori Mammoto, Akiko Mammoto, Mathumai KanapathipillaiUniversity of Michigan-Dearborn. Medical College of Wisconsin. United States MoleculesMolecules 2026; 31: DOI: 10.3390/molecules31193511 AbstractPulmonary arterial hypertension (PAH) is a devastating disease driven largely by oxidative stress and inflammation. The pulmonary arterial endothelium plays a key role in PAH pathogenesis. In this

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Clinical characteristics and severity classification in Mixed Connective Tissue Disease: a nationwide retrospective study

Satoshi Kubo, Yurie Kanda, Hideto Kameda, Masataka Kuwana, Hidehiko Narazaki, Takao Fujii, Keishi Fujio, Yoshinao Muro, Konomi Akamatsu, Koichiro Ohmura, Takehisa Ogura, Yuichiro Shirai, Yujiro Tanabe, Ran Nakashima, Yumi Tsuchida, Shingo Nakayamada, Hisanori Hasegawa, Shintaro Hirata, Shusaku Fukaya, Takashi Kato, Hidekata Yasuoka, Yuta Yamashita, Michihito Kono, Tatsuya Atsumi, Yoshiya TanakaUniversity of Occupational and Environmental Health,

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Macrophages Contribute to Pulmonary Hypertension Associated With Sickle Cell Disease

Christina Lisk, Francesca Cendali, Natalie Westover, Delaney Swindle, Daniel Colon Hidalgo, Caitlin Lewis, Melissa J. Lucero, Nishant K. Rana, Gemlyn George, Saini Setua, Monika Dzieciatkowska, Kathryn Hassel, Christy S. Niemeyer, Kurt Stenmark, Eva Nozik, Angelo D’Alessandro, Paul W. Buehler, David C. IrwinUniversity of Colorado Denver – Anschutz Medical Campus. Children’s Hospital Colorado. University of Maryland

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