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Animal models of pulmonary arterial hypertension associated with atrial septal defect

Li Wang, Ting Tang, Xiaochun Tian, Chang Peng, Shuqi WuGuizhou Children’s Hospital and Affiliated Hospital of Zunyi Medical University. China Scientific ReportsSci Rep 2024; 14: DOI: 10.1038/s41598-024-69002-5 AbstractPulmonary arterial hypertension (PAH) is a well-known complication of congenital heart disease (CHD). The lack of a satisfactory animal model for PAH associated with CHD (PAH-CHD) has limited progress […]

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Echocardiographic estimation of pulmonary arterial and right atrial pressures in children with congenital heart disease: a comprehensive prospective study and introduction of novel equations

Elaheh Malakan Rad, Reza Elhamian, Keyhan Sayadpour Zanjani, Reza Shabanian, Ehsan Aghaei Moghadam, Mohamad Taghi Majnoon, Aliakbar ZeinalooChildren’s Medical Center and Tehran University of Medical Sciences.Iran Journal of Cardiovascular ImagingJ Cardiovasc Imag 2024; 32: DOI: 10.1186/s44348-024-00023-4 AbstractBackground: Pediatric pulmonary hypertension (PH) is characterized by a mean pulmonary arterial pressure exceeding 20 mmHg. There is limited research on

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Pediatric Chylothorax Treated With Lymphangiography and Thoracic Duct Embolization: A Case Report

Harneet Sangha, Nathan G. Savolainen, Douglas A. Murrey, Jason S. VergnaniElson S. Floyd College of Medicine. Inland Imaging.United States CureusCureus 2024; 16: DOI: 10.7759/cureus.63981 AbstractA chylothorax, the accumulation of lymphatic fluid in the pleural space, may occur for a variety of reasons. It is commonly seen in adults post-thoracic surgery. We present the case of a

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Adenylyl Cyclase Isoform 6 in the Pulmonary Artery Is Inhibited by Hypoxia via Cysteine Nitrosylation

Saeid Maghsoudi, Vikram Bhatia, Martha Hinton, Nisha Singh, Modh Wasif Khan, Prashen Chelikani, Shyamala, DakshinamurtiUniversity of Manitoba Faculty of Health Sciences. University of Manitoba Children’s Hospital Research Institute of Manitoba. University of Manitoba College of Dentistry. Canada American Journal of Respiratory Cell and Molecular BiologyAm J Respir Cell Mol Biol 2024; DOI: 10.1165/rcmb.2023-0447OC AbstractPersistent pulmonary hypertension

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Hybrid treat-and-repair strategy for large patent ductus arteriosus: a proof-of-concept case report

Naoki Tsuboya, Yoshihide Mitani, Hiroyuki Ohashi, Hirofumi Sawada, Masahiro HirayamaMie University Graduate School of Medicine.Japan European Heart Journal Case ReportsEur Heart J Case Rep 2024; DOI: 10.1093/ehjcr/ytae354 AbstractBackground: In cases of atrial septal defect with pulmonary arterial hypertension (PAH), a treat-and-repair strategy that adopts pulmonary vasodilator therapy and subsequent defect closure is postulated to be effective. However,

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Prenatal Prognosis of Omphalocele Using Magnetic Resonance Imaging Measurement of Fetal Lung Volumes

Simon E. Dadoun, Matthew A. Shanahan, Christian M. Parobek, Brian A. Burnett, Alice King, Pamela Ketwaroo, Roopali V. Donepudi, April D. AdamsTexas Children’s Hospital and Baylor College of Medicine. United States American Journal of Obstetrics and Gynecology Maternal Fetal MedicineAm J Obstet Gynecol MFM 2024; DOI: 10.1016/j.ajogmf.2024.101457 AbstractBackground: Omphalocele is a congenital midline abdominal wall defect resulting

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Safety and Effectiveness of Selexipag in Pediatric Pulmonary Hypertension: A Retrospective Multi-Center Cohort Study

Benjamin S. Frank, Eliza R. Gentzler, Catherine M. Avitabile, Kathleen Miller-Reed, Zhaoxing Pan, Erika B. Rosenzweig, D. Dunbar Ivy, Usha S. KrishnanUniversity of Colorado School of Medicine and Children’s Hospital Colorado. Columbia University Irving Medical Center and Morgan Stanley Childrens Hospital of New York Presbyterian Hospital. University of Pennsylvania School of Medicine and Children’s Hospital

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Circulating High Mobility Group Box-1 Does Not Predict Pulmonary Arterial Hypertension in Children with Congenital Heart Disease: A Prospective Cohort Study

Bruno Caracci, Carolyne Pehora, Lee Benson, Benjamin E. Steinberg, Neil M. Goldenberg, Katherine TaylorHospital for Sick Children and University of Toronto. Canada Journal of Cardiothoracic and Vascular AnesthesiologyJ Cardiothorac Vasc Anesthesiol 2024; DOI: 10.1053/j.jvca.2024.07.020 AbstractObjectives: Pulmonary arterial hypertension (PAH) is a devastating complication of pediatric congenital heart disease (CHD). A recent study has identified the protein high

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Neonatal neuroblastoma presenting as recurrent chylothorax in a hydropic baby: A case report

Daniah S. Alhazmi, Maha BamehrezKing Faisal Specialist Hospital and Research Center.Saudi Arabia Journal of Family Medicine and Primary CareJ Family Med Prim Care 2024; 13: 2780-2783DOI: 10.4103/jfmpc.jfmpc_992_23 AbstractWe report here a rare case of neuroblastoma in a neonate who presented as a hydropic baby with respiratory distress due to recurrent chylothorax. The neuroblastoma regressed after six

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Clinical presentation and surgical outcomes in patients with Shone’s complex: a systematic review

H. Shafeeq Ahmed, Purva Reddy Jayaram, Deeksha GuptaBangalore Medical College and Research Institute.India General Thoracic and Cardiovascular SurgeryGen Thorac Cardiovasc Surg 2024; DOI: 10.1007/s11748-024-02067-1 AbstractObjective: Shone’s complex comprises of a combination of congenital cardiac anomalies causing obstructions in the left ventricle’s inflow and outflow tracts. This systematic review aims to evaluate the clinical features and surgical outcomes

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