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KLF6 activation marks an angiogenic and apoptosis resistant endothelial phenotype in pulmonary arterial hypertension

Rehab Alharbi, Merve Keles, Nadia Fernandes, Hannah Maude, Adam Fellows, Richard D. Williams, Chien-Nien Chen, Nathalie Lambie, Nik Matthews, May Al-Sahaf, Sam N. Barnett, Minzhe Guo, Lan Zhao, Allan Lawrie, Jeffrey A. Whitsett, Inês Cebola, Beata Wojciak-StothardImperial College London. University of Hafr Al Batin. Hammersmith Hospital. Cincinnati Children’s Hospital Medical Center and University of Cincinnati

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Clinical phenotypes and mortality predictors in pediatric critical pertussis: A multinational study

Mohammad Alghounaim, Naila A. Shaheen, Abdulrahman Aldaithan, Saif Awlad Thani, Yasser Kazzaz, Abdulla Alfraij, On behalf of the Gulf Pediatric Pertussis Study (GPPS) Group Amiri Hospital, Ministry of Health. King Abdullah International Medical Research Center. King Saud bin Abdulaziz University for Health Sciences. Farwaniya Hospital. Royal Hospital.Kuwait, Saudi Arabia and Oman Journal of Infection and

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Atrioventricular septal defect repair with severe pulmonary arterial hypertension: A novel surgical approach using a valved Potts shunt

Bastien Provost, Emmanuelle Fournier, Estibaliz Valdeolmillos, Guy Vaksmann, Emre BelliMarie Lannelongue Hospital. Hôpital Privé de La Louvière.France Journal of Thoracic and Cardiovascular Surgery TechniquesJTCVS Tech 2026; 47: DOI: 10.1016/j.xjtc.2026.102304 AbstractAbstract Not Available CategoryClass I. Pulmonary Hypertension Associated with Congenital Cardiovascular DiseaseSurgical and Catheter-mediated Interventions for Pulmonary Vascular Disease Age Focus: Pediatric Pulmonary Vascular Disease Fresh or

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Case Report: Prolonged extracorporeal membrane oxygenation as a deliberate operative adjunct for tracheobronchial reconstruction in a child with invasive aspergillosis

Marcin Łosin, Wojciech Karolak, Romuald Lango, Witold Rzyman, Monika Rosinski, Weronika Lotkowska, Piotr CzaudernaMedical University of Gdansk and University Clinical Center.Poland Frontiers in PediatricsFront Pediatr 2026; 14: DOI: 10.3389/fped.2026.1843892 AbstractWe report the case of a 6-year-old boy with newly diagnosed type 1 diabetes mellitus presenting in diabetic ketoacidosis, who developed a massive acquired tracheo-esophageal fistula (TEF)

Case Report: Prolonged extracorporeal membrane oxygenation as a deliberate operative adjunct for tracheobronchial reconstruction in a child with invasive aspergillosis Read More »

Single-center experience with aortopexy in pediatric tracheomalacia: a case series

Ali Tadayon, Shayan Yousufzai, Mehdi Forooghi, Shahdokht Abooali, Parisa Zare, Hossein Hosseini, Alireza Yousefi, Mostafa Poorkhosravani, Mostafa Moqadas, Omidreza AzhNamazi Hospital and Shiraz University of Medical Sciences.Iran Journal of Cardiothoracic SurgeryJ Cardiothorac Surg 2026; DOI: 10.1186/s13019-026-04415-z AbstractBackground: Tracheomalacia in infants often results from vascular compression and is frequently associated with multiple congenital anomalies. Aortopexy is a well-established

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Disease-related complications and risk factors in hemoglobin H disease in a Thai multicenter registry

Nattiya Teawtrakul, Duantida Songdej, Chattree Hantaweepant, Adisak Tantiworawit, Sasinee Hantrakool, Pornpun Sripornsawan, Pacharapan Surapolchai, Supanun Lauhasurayotin, Kitti Torcharus, Pranee Sutcharitchan, Noppacharn Uaprasert, Krissana Panrong, Napat Laoaroon, Patcharee Komvilaisak, Panachai Silpsamrit, Arunotai Meekaewkunchorn, Bunchoo Pongtanakul, Pimlak Charoenkwan & Red Blood Cell Disorders Study GroupSrinagarind Hospital and Khon Kaen University. Ramathibodi Hospital, Siriraj Hospital and Mahidol University.

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Clinical Factors Associated with Ventilator-Free Days in Newborns with Persistent Pulmonary Hypertension of the Newborn: A Retrospective Cohort Study in Thailand

Sirichan Larpnarongchai, Gunlawadee Maneenil, Anucha Thatrimontrichai Supaporn Dissaneevate, Manapat Praditaukrit, Pattima PakhathirathienPrince of Songkla University.Thailand Journal of Clinical MedicineJ Clin Med 2026; 15: DOI: 10.3390/jcm15114377 AbstractBackground/Objectives: Ventilator-free days (VFDs) are a useful composite measure to assess both survival and duration of mechanical ventilation in critically ill patients. This study aimed to determine the factors associated with

Clinical Factors Associated with Ventilator-Free Days in Newborns with Persistent Pulmonary Hypertension of the Newborn: A Retrospective Cohort Study in Thailand Read More »

Contemporary Endothelial Genome Editing Technologies: Towards Precision Genetic Medicine for Vascular Diseases

You-Yang Zhou, Colin E. EvansAnn and Robert H. Lurie Children’s Hospital of Chicago and Northwestern University Feinberg School of Medicine. United States International Journal of Molecular SciencesInt J Mol Sci 2026; 27: DOI: 10.3390/ijms27115100 AbstractEndothelial dysfunction is a key characteristic of many diseases, including atherosclerosis, hypertension, heart failure, stroke, cancer, acute respiratory distress syndrome (ARDS), peripheral

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Evaluation and Management of Genetic Respiratory Disorders Presenting as Hypoxemic Respiratory Failure in the Newborn Infant

Jennifer A. Wambach, F. Sessions Cole, Lawrence M. NogeeWashington University School of Medicine and St. Louis Children’s Hospital. Johns Hopkins University. United States Clinics in PerinatologyClin Perinatol 2026; 53: 381-401DOI: 10.1016/j.clp.2026.03.003 AbstractHypoxemic respiratory failure is a common reason for admission to the neonatal intensive care unit for term and late preterm infants. Some infants have rare

Evaluation and Management of Genetic Respiratory Disorders Presenting as Hypoxemic Respiratory Failure in the Newborn Infant Read More »

Management of Hypoxemic Respiratory Failure in the Newborn During Therapeutic Hypothermia

Paulina Hume, Luna Khanal, Satyan Lakshminrusimha, Deepika SankaranUniversity of California, Davis.United States Clinics in PerinatologyClin Perinatol 2026; 53: 317-332DOI: 10.1016/j.clp.2026.02.008 AbstractTherapeutic hypothermia (TH) is the gold standard for the management of hypoxic ischemic encephalopathy (HIE) in newborns. Both hypoxia and TH may contribute to an increase in pulmonary vascular resistance (PVR), resulting in persistent pulmonary hypertension

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