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Pulmonary venous obstruction following correction for total anomalous pulmonary venous drainage: a challenge

H. J. van der Wal, D. I. Hamilton, Michael J. Godman, Leon K. Lacquet, Anton van OortWilhelmina Children’s Hospital.Netherlands European Journal of Cardiothoracic SurgeryEur J Cardiothorac Surg 1992; 6: 545-549DOI: 10.1016/1010-7940(92)90006-j AbstractPulmonary venous obstruction after surgical correction of total anomalous pulmonary venous drainage (TAPVD) is a serious condition. Pulmonary venous obstruction can be the result of […]

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Alterations in elastin and collagen related to the mechanism of progressive pulmonary venous obstruction in a piglet model. A hemodynamic, ultrastructural, and biochemical study

Jay I. LaBourene, John G. Coles, Dorothy J. Johnson, Arun Mehra, Fred W. Keeley, Marlene RabinovitchHospital for Sick Children.Canada Circulation ResearchCirc Res 1990; 66: 438-456DOI: 10.1161/01.res.66.2.438 AbstractWe created an animal model to understand better the pathogenesis and underlying mechanism of progressive central pulmonary venous (PV) obstruction, a condition not amenable to current therapy. Twenty piglets underwent

Alterations in elastin and collagen related to the mechanism of progressive pulmonary venous obstruction in a piglet model. A hemodynamic, ultrastructural, and biochemical study Read More »

A sutureless technique for the relief of pulmonary vein stenosis with the use of in situ pericardium

Hani K. Najm, Christopher A. Caldarone, Jeffery Smallhorn, John G. ColesHospital of Sick Children and University of Toronto.Canada Journal of Thoracic and Cardiovascular SurgeryJ Thorac Cardiovasc Surg 1998; 115: 468-470DOI: 10.1016/S0022-5223(98)70294-6 AbstractAbstract Not Available CategorySegmental Pulmonary Venous Disease. Without a Focus on Pulmonary HypertensionSurgical and Catheter-mediated Interventions for Pulmonary Vascular Disease Age Focus: Pediatric Pulmonary Vascular

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Conventional and sutureless techniques for management of the pulmonary veins: Evolution of indications from postrepair pulmonary vein stenosis to primary pulmonary vein anomalies

Tae-Jin Yun, John G. Coles, Igor E. Konstantinov, Osman O. Al-Radi, Rachel M. Wald, Vitor Guerra, Nilto C. de Oliveira, Glen S. Van Arsdell, William G. Williams, Jeffrey Smallhorn, Christopher A. CaldaroneHospital for Sick Children and University of Toronto.Canada Journal of Thoracic and Cardiovascular SurgeryJ Thorac Cardiovasc Surg 2005; 129: 167-174DOI: 10.1016/j.jtcvs.2004.08.043 AbstractObjective: We have previously reported

Conventional and sutureless techniques for management of the pulmonary veins: Evolution of indications from postrepair pulmonary vein stenosis to primary pulmonary vein anomalies Read More »

Factors associated with mortality and reoperation in 377 children with total anomalous pulmonary venous connection

Tara Karamlou, Rebecca Gurofsky, Eisar Al Sukhni, John G. Coles, William G. Williams, Christopher A. Caldarone, Glen S. Van Arsdell, Brian W. McCrindleUniversity of Toronto and Hospital for Sick Children.Canada CirculationCirculation 2007; 115: 1591-1598DOI: 10.1161/CIRCULATIONAHA.106.635441 AbstractBackground: We sought to determine era-specific changes in the incidence of mortality and reoperation in children with total anomalous pulmonary venous connection.Methods and results: We reviewed the records of 377 children presenting from

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Outcomes after surgical treatment of children with partial anomalous pulmonary venous connection

Bahaaldin Alsoufi, Sally Cai, Glen S. Van Arsdell, William G. Williams, Christopher A. Caldarone, John G. ColesHospital for Sick Children and University of Toronto.Canada Annals of Thoracic SurgeryAnn Thorac Surg 2007; 84: 2020-2026DOI: 10.1016/j.athoracsur.2007.05.046 AbstractBackground: We explore early results and time-related morbidity after surgical repair of partial anomalous pulmonary venous connection (PAPVC) at our institution.Methods: Between 1982 and

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Primary sutureless repair for infants with mixed total anomalous pulmonary venous drainage

Osami Honjo, Cori R. Atlin, Barbara C. S. Hamilton, Osman Al-Radi, Nicola Viola, John G. Coles, Glen S. Van Arsdell, Christopher A. CaldaroneHospital for Sick Children.Canada Annals of Thoracic SurgeryAnn Thorac Surg 2010; 90: 862-868DOI: 10.1016/j.athoracsur.2010.05.007 AbstractBackground: Mixed type total anomalous pulmonary venous drainage (TAPVD) poses technical challenges and high mortality owing to diminutive size and remote

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Primary pulmonary vein stenosis: the impact of sutureless repair on survival

Nicola Viola, Abdullah A. Alghamdi, Donald G. Perrin, Gregory J. Wilson, John G. Coles, Christopher A. CaldaroneSouthampton University Hospital.United Kingdom and Canada Journal of Thoracic and Cardiovascular SurgeryJ Thorac Cardiovasc Surg 2011; 142: 344-350DOI: 10.1016/j.jtcvs.2010.12.004 AbstractBackground: Primary pulmonary vein stenosis is often associated with relentless restenosis and early death. During the last 2 decades, we have developed

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Pulmonary vasodilators and exercise in Fontan circulation: a systematic review and meta-analysis

Diamantis Kosmidis, Alexandra Arvanitaki, Ioannis T Farmakis, Aris Liakos, Andreas Giannopoulos, Antonios Ziakas, George GiannakoulasAristotle University of Thessaloniki. Royal Brompton Hospital. University Medical Center Mainz. Greece, United Kingdom and Germany HeartHeart 2023; DOI: 10.1136/heartjnl-2023-323166 AbstractObjective: In Fontan circulation, pulmonary arterial hypertension (PAH)-targeted therapies could improve the patients’ exercise capacity. This study aimed to investigate the effects of PAH

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CAR Selectively Enhances the Pulmonary Vasodilatory Effect of Fasudil in a Microsphere Model of Pulmonary Hypertension

Abraham Rothman, Humberto Restrepo, William N. Evans, Valeri Sarukhanov, David MannUniversity of Nevada Las Vegas. Vascular BioSciences.United States Open Respiratory Medicine JournalOpen Respir Med J 2023; DOI: 10.2174/18743064-v17-e230404-2022-19 AbstractBackground: Despite the approval of several medications for pulmonary hypertension, morbidity and mortality are unacceptably high. Systemic hypotension may limit the use of pulmonary hypertension medications.Objectives: This study aimed to

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