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Cardiac medical conditions have become the leading cause of death in children with heart disease

Tobias R. Schlingmann, Ravi R. Thiagarajan, Kimberlee Gauvreau, Kimberly C. Lofgren, Michael Zaplin, Jean A. Connor, Pedro J. del Nido, James E. Lock, Kathy J. JenkinsChildren’s Hospital Boston and Harvard Medical School.United States Congenital Heart DiseaseCongenit Heart Dis 2012; 7: 551-558DOI: 10.1111/j.1747-0803.2012.00674.x AbstractObjective: Mortality among children with congenital and acquired heart disease has decreased significantly over the […]

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The Role of Elevated Wall Shear Stress in Progression of Pulmonary Vein Stenosis: Evidence from Two Case Studies

Peter E. Hammer, Kerry McEnaney, Ryan Callahan, Christopher W. Baird, David M. Hoganson, Kathy J. JenkinsBoston Children’s Hospital.United States ChildrenChildren 2021; 8:DOI: 10.3390/children8090729 AbstractPulmonary vein stenosis is a serious condition characterized by restriction or blockage due to fibrotic tissue ingrowth that develops in the pulmonary veins of infants or children. It is often progressive and can

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Continuous Positive Airway Pressure in the Treatment of Pediatric High Altitude Pulmonary Edema: A Case Study

Ryan Hodnick, Michael L. Cohen, Joseph B. Loehner, Jennifer MazzantiTrans Aero Medevac. TriState CareFlight.United States Wilderness and Environmental MedicineWilderness Environ Med 2024; DOI: 10.1177/10806032231222003 AbstractTreatment of high altitude pulmonary edema (HAPE) can be challenging and is further complicated in the pediatric patient in the prehospital environment. The following case presents a decompensating pediatric patient with HAPE in the prehospital

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Elevated transaminases in congenital central hypoventilation syndrome

Rachel Y. Wang, Victoria S. Wang, Thomas G. Keens, Yan Chai, Nisreen Soufi, Iris A. PerezChildren’s Hospital Los Angeles.United States European Respiratory Journal Open ResearchERJ Open Res 2024; 10:DOI: 10.1183/23120541.00658-2023 AbstractPatients with CCHS who also have Hirschsprung disease, elevated or low BMI, or pulmonary hypertension may be predisposed to elevated transaminases and may need periodic follow-up

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Therapy in pediatric pulmonary hypertension: memoire of an unfinished journey

Martin Hosking, Angela BatesUniversity of British Columbia. University of Alberta.Canada Canadian Journal of CardiologyCan J Cardiol 2024;DOI: 10.1016/j.cjca.2024.02.009 AbstractAbstract Not Available CategoryMedical Therapy. Efficacy or Lack of Efficacy Age Focus: Pediatric Pulmonary Vascular Disease Fresh or Filed Publication: Filed (PHiled). Greater than 1-2 years since publication Article AccessFree PDF File or Full Text Article Available Through

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Application of a modified clinical classification for pulmonary arterial hypertension associated with congenital heart disease in children: emphasis on atrial septal defects and transposition of the great arteries. An analysis from the TOPP registry

Julie Wacker, Tilman Humpl, Rolf M. F. Berger, Dunbar Ivy, David Bowers, Damien Bonnet, Maurice Beghetti on behalf of the TOPP InvestigatorsChildren’s University Hospital and University of Geneva. Hospital for Sick Children and University of Toronto. Beatrix Children’s Hospital, University Medical Center Groningen and University of Groningen. Children’s Hospital Colorado and University of Colorado School

Application of a modified clinical classification for pulmonary arterial hypertension associated with congenital heart disease in children: emphasis on atrial septal defects and transposition of the great arteries. An analysis from the TOPP registry Read More »

Long-term safety and tolerability of ambrisentan treatment for pediatric patients with pulmonary arterial hypertension: An open-label extension study

Dunbar Ivy, Maurice Beghetti, Ernesto Juaneda‑Simian, Ramiya Ravindranath, Mary Ann Lukas, Sandra Machlitt‑Northen, Nicola Scott, Jun Narita, Rolf M. F. BergerChildren’s Hospital Colorado. University Children’s Hospital HUG and University of Geneva. Hospital de Niños de la Santísma Trinidad. Glaxo-Smith-Kline. Osaka University Graduate School of Medicine. Beatrix Children’s Hospital, University Medical Center Groningen and University of

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Increased Elastase and Matrix Metalloproteinase Levels in the Pulmonary Arteries of Infants With Congenital Diaphragmatic Hernia

Jui-Hsia Hung, Stéphanie Langlois, Meagen Weibe, Benjamin Wild, Jessica Barré-Dunn, Kyle N. CowanUniversity of Ottawa and Children’s Hospital of Eastern Ontario. Canada Journal of Pediatric SurgeryJ Pediatr Surg 2024;DOI: 10.1016/j.jpedsurg.2024.01.028 AbstractBackground: Pulmonary vascular disease (PVD) complicated with pulmonary hypertension (PH) is a leading cause of mortality in congenital diaphragmatic hernia (CDH). Unfortunately, CDH patients are often resistant

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Outcome following acute and recurrent rheumatic fever

Suchaya Silvilairat, Artit Sornwai, Saviga Sethasathien, Kwannapas Saengsin, Krit Makonkawkeyoon, Rekwan Sittiwangkul, Yupada PongprotChiang Mai University.Thailand Pediatrics and International Child HealthPediatr Int Child Health 2024;DOI: 10.1080/20469047.2024.2313330 AbstractBackground: Rheumatic carditis is the leading cause of permanent disability caused by damage of the cardiac valve. This study aimed to determine the outcome and predictors of valve surgery in patients

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Health-Related Quality of Life Across the Spectrum of Pulmonary Hypertension

Aparna Balasubramanian, Brett Larive, Evelyn M. Horn, Hiliary M. DuBrock, Reena Mehra, Miriam Jacob, Anna R. Hemnes, Jane A. Leopold, Milena K. Radeva, Nicholas S. Hill, Serpil C. Erzurum, Erika Berman-Rosenzweig, Robert Frantz, Franz P. Rischard, Gerald Beck, Paul M. Hassoun, Stephen C. Mathai, PVDOMICS Study GroupJohns Hopkins University. Cleveland Clinic. Weill Cornell Medicine. Mayo

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