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Plasma mid-regional proadrenomedullin level in children with pulmonary hypertension associated with CHD

Shimaa A. Elesawy, Hesham A. El-Serogy, Esraa A. Sorour, Amr M. Zoairar Elsalam General Hospital and Ministry of Health. Tanta University. Egypt Cardiology in the YoungCardiol Young 2023; DOI: 10.1017/S1047951123000471 AbstractAdrenomedullin has been shown to inhibit proliferation in pulmonary artery smooth muscle cells and to alleviate pulmonary artery collagen accumulation in pulmonary hypertension. We aimed to

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WNT7A deficit is associated with dysfunctional angiogenesis in pulmonary arterial hypertension

Ananya Chakraborty, Abinaya Nathan, Mark Orcholski, Stuti Agarwal, Elya A. Shamskhou, Natasha Auer, Ankita Mitra, Eleana Stephanie Guardado, Gowri Swaminathan, David F. Condon, Joyce Yu, Matthew McCarra, Nicholas H. Juul, Alden Mallory, Roberto A. Guzman-Hernandez, Ke Yuan, Vanesa Rojas, Joseph T. Crossno, Lai-Ming Yung, Paul B. Yu, Thomas Spencer, Robert A. Winn, Andrea Frump, Vijaya

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Fatal Pulmonary Veno-Occlusive Disease and Systemic Juvenile Idiopathic Arthritis: Case Report and Literature Review

Silvia Escalada-Pellitero, Alberto García-Salido, Daniel Clemente-Garulo, Daniel Azorín-Cuadrillero, Gema De Lama Caro-Patón, Juan Carlos López-RobledilloHospital Infantil Universitario Niño Jesús. Spain Rheumatologia ClinicaRheumatol Clin 2023; 19: 53-56DOI: 10.1016/j.reumae.2022.12.001 AbstractSystemic juvenile idiopathic arthritis (sJIA) is a chronic childhood inflammatory disease. SJIA accounts for approximately 5-15 per cent of all cases of JIA and has a high morbidity and

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Pathological Roles for Endothelial Colony-Forming Cells in Neonatal and Adult Lung Disease

Jason O. Robertson, Serpil C. Erzurum, Kewal AsosinghCleveland ClinicUnited States American Journal of Respiratory Cell and Molecular BiologyAm J Respir Cell Mol Biol 2023; 68: 13-22DOI: 10.1165/rcmb.2022-0318PS AbstractEndothelial colony-forming cells (ECFCs) are vascular resident and circulating endothelial cell subtypes with potent angiogenic capacity, a hierarchy of single-cell clonogenic potentials, and the ability to participate in de novo blood

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Pulmonary Histopathologic Findings in Pediatric Patients After Hematopoietic Stem Cell Transplantation: An Autopsy Study

Nahir Cortes-Santiago, Kalyani R. Patel, Hao Wu, Sara E. Sartain, Saleh Bhar, Manuel Silva-Carmona, Jennifer PogorilerTexas Children’s Hospital and Baylor College of Medicine. Yale School of Medicine and Yale New Haven Hospital. Children’s Hospital of Philadelphia.United States Pediatric and Developmental PathologyPediatr Dev Pathol 2023; DOI: 10.1177/10935266231170101 AbstractBackground: Pathologic characterization of pulmonary complications following hematopoietic stem cell transplantation

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Effect of prenatal diaphragmatic hernia on pulmonary arterial morphology

Andrew V. Stainsby, Philip L. J. DeKoninck, Kelly J. Crossley, Alison Thiel, Megan J. Wallace, James T. Pearson, Aidan J. Kashyap, Michelle K. Croughan, Beth A. Allison, Ryan Hodges, Marta Thio, Andreas W. Flemmer, Erin V. McGillick, Arjan B. te Pas, Stuart B. Hooper, Marcus J. KitchenHudson Institute of Medical Research, Victoria Heart Institute and

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Vascular and pulmonary effects of ibuprofen on neonatal lung development

Xueyu Chen, Dongshan Han, Xuan Wang, Xuemei Huang, Zilu Huang, Yijun Liu, Junyan Zhong, Frans J. Walther, Chuanzhong Yang, Gerry T. M. WagenaarAffiliated Shenzhen Maternity and Child Healthcare Hospital, The First School of Clinical Medicine, Southern Medical University. David Geffen School of Medicine, University of California Los Angeles. Lundquist Institute for Biomedical Innovation at Harbor-UCLA

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Nitration-mediated activation of the small GTPase RhoA stimulates cellular glycolysis through enhanced mitochondrial fission

Qing Lu, Xutong Sun, Manivannan Yegambaram, Wojciech Ornatowski, Xiaomin Wu, Hui Wang, Alejandro Garcia-Flores, Victoria Da Silva, Evgen A. Zemskov, Haiyang Tang, Jeffrey R. Fineman, Kim Tieu,Ting Wang, Stephen M. BlackFlorida International University. University of Arizona Health Sciences. University of California San Francisco. United States Journal of Biological ChemistryJ Biol Chem 2023; 299:DOI: 10.1016/j.jbc.2023.103067 AbstractMitochondrial fission

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Pulmonary Vascular Phenotypes of Prematurity: The Path to Precision Medicine

Hussnain Mirza, Erica Mandell, John P. Kinsella, Patrick J. McNamara, Steven H. Abmandvent Health for Children and UCF College of Medicine. University of Iowa School of Medicine. University of Colorado Anschutz School of Medicine and Children’s Hospital Colorado.United States Journal of PediatricsJ Pediatr 2023; DOI: 10.1016/j.jpeds.2023.113444 AbstractPulmonary hypertension (PH) is associated with significant morbidities and high

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Hereditary pulmonary arterial hypertension burden in pediatrics: A single referral center experience

Maki Ishizuka, Wenxin Zou, Elise Whalen, Erin Ely, Ryan D. Coleman, Dolores H. Lopez-Terrada, Daniel J. Penny, Yuxin Fan, Nidhy P. VargheseBaylor College of Medicine, Texas Children’s Hospital. United States Frontiers in PediatricsFron Pediat 2023; 11: DOI: 10.3389/fped.2023.1050706 AbstractIntroduction: Hereditary pulmonary arterial hypertension (HPAH) is a rare yet serious type of pulmonary arterial hypertension (PAH). The burden

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