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A Novel Rat Model for Group 2 Pulmonary Hypertension by Total Pulmonary Vein Banding: Multi-Omics Insights into Pathophysiological Mechanisms

Jin Shentu, Wenxuan Dai, Chang Chen, Jiawei Huang, Lijun Chen, Yi Yan, Han Zhang, Zhongqun Zhu, Guocheng Shi, Huiwen ChenShanghai Children’s Medical Center and Shanghai Jiao Tong University School of Medicine. China Journal of Thoracic and Cardiovascular SurgeryJ Thorac Cardiovasc Surg 2026; DOI: 10.1016/j.jtcvs.2026.01.017 AbstractObjectives: Group 2 pulmonary hypertension (PH) remains a highly morbid disease, yet no […]

A Novel Rat Model for Group 2 Pulmonary Hypertension by Total Pulmonary Vein Banding: Multi-Omics Insights into Pathophysiological Mechanisms Read More »

Expanding the phenotypic spectrum of MECOM-associated syndrome: rare variants are associated with syndromic pulmonary arterial hypertension

Carrie L. Welch , Meriel McEntagart, Shahin Moledina, Cara Morgan, Emilia Swietlik, Chao Hou, Lu Qiao, Emily Callejo, Savanna Craib, Damian Smedley, Emilia K. Bijlsma, Patrice Bouvagnet, Nahir Cortes-­Santiago, Tamir Dagan, Jacqueline Eason, Frances Flinter, Aakash Joshi, Jeremie Mortreux, Fadel E. Ruiz, Deborah Shears, Celia Azevedo Soares, Nidhy P. Varghese, Wendy K ChungBoston Children’s Hospital,

Expanding the phenotypic spectrum of MECOM-associated syndrome: rare variants are associated with syndromic pulmonary arterial hypertension Read More »

Mechanisms underlying end-organ injury in sleep apnea

Mohammad Badran, Rene Cortese, Alex Gileles-Hillel, David GozalUniversity of Missouri. University of Kansas Medical Center. Hebrew University of Jerusalem. Joan C. Edwards School of Medicine and Marshall University.United States and Israel European Respiratory JournalEur Respir J 2026; DOI: 10.1183/13993003.02397-2025 AbstractOSA is a prevalent chronic condition characterized by repetitive upper airway collapse that promotes the occurrence of

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Successful bridge to diagnosis: Extracorporeal life support in generalized arterial calcification of infancy

Sarah D. King, Spencer Wilhelm, Ruth Lewit, Erin E. Perrone, Arul ThirumoorthiUniversity of Michigan,.United States PerfusionPerfusion 2026; DOI: 10.1177/02676591261420652 AbstractIntroduction: Generalized arterial calcification of infancy (GACI) is a rare, difficult to recognize, autosomal recessive disorder with high neonatal mortality due to vascular calcification and cardiopulmonary collapse.Case Report: We report a term female presenting with persistent pulmonary

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Long Non-Coding RNA MALAT1 Regulates HMOX1 in Sickle Cell Disease-Associated Pulmonary Hypertension

Viranuj Sueblinvong, Sarah S. Chang, Jing Ma, David R. Archer, Solomon Ofori-Acquah, Roy L. Sutliff, Changwon Park, C. Michael Hart, Benjamin T. Kopp, Bum-Yong KangEmory University School of Medicine. Atlanta Veterans Affairs Healthcare System. National Institutes of Health. Louisiana State University Health Science Center. United States CellsCells 2026; 15: DOI: 10.3390/cells15020154 AbstractPulmonary hypertension (PH) causes morbidity

Long Non-Coding RNA MALAT1 Regulates HMOX1 in Sickle Cell Disease-Associated Pulmonary Hypertension Read More »

Prevalence and severity of persistent pulmonary hypertension of the newborns among asphyxiated neonates admitted in Enugu State University Teaching Hospital

Ani Okechukwu, Odutola Odetunde, Ekwochi Uchenna, Josephat M ChinawaEnugu State University College of Medicine. University of Nigeria Teaching Hospital Ituku/Ozalla and University of Nigeria ItukuNigeria British Medical Journal Paediatrics OpenBMJ Paediatr Open 2026; 10: DOI: 10.1136/bmjpo-2025-004351 AbstractBackground: Persistent pulmonary hypertension of newborns (PPHN) is an acute neonatal disorder with a high mortality rate despite several advances in

Prevalence and severity of persistent pulmonary hypertension of the newborns among asphyxiated neonates admitted in Enugu State University Teaching Hospital Read More »

Microbiome-Metabolome Axis in BALF Reveals Novel Diagnostic Biomarkers for Congenital Heart Disease-Associated Pulmonary Arterial Hypertension

Xiaoyu Zhang, Liming Cheng, Yuan Zhou, Jiahui Xie, Wenting Gui, Jiaxiang Chen, Zidan Zhang, Kai Liu, Runwei MaFuwai Yunnan Hospital, Chinese Academy of Medical Sciences, Affiliated Cardiovascular Hospital of Kunming Medical University. Kunming Children’s Hospital.China Journal of Cardiovascular Development and DiseaseJ Cardiovasc Dev Dis 2026; 13: DOI: 10.3390/jcdd13010032 AbstractBackground: Early identification of irreversible pulmonary vascular remodeling in

Microbiome-Metabolome Axis in BALF Reveals Novel Diagnostic Biomarkers for Congenital Heart Disease-Associated Pulmonary Arterial Hypertension Read More »

Infant with Complex Congenital Cardiac Anomalies: A Case Report and Review of Literature

Aliasgar Taha, Abdullah Ahmed Tariq, Yusur Abbas Mahmood, Leah Leslie Dias, Rahul Binu, Subhranshu Sekhar Kar, Alaa Mohamad HussainRas Al Khaimah Medical and Health Sciences University.United Arab Emirits Annals of African MedicineAnn Afr Med 2026; DOI: 10.4103/aam.aam_631_25 AbstractThe coexistence of multiple complex congenital cardiac anomalies in a single infant – particularly unbalanced Atrioventricular Septal Defect; Double

Infant with Complex Congenital Cardiac Anomalies: A Case Report and Review of Literature Read More »

The relationship between muscle strength and oxygenation and activities of daily living in adolescents and young adults with pulmonary arterial hypertension

Jan Dik, Ceyhun Topcuoglu, Naciye Vardar-Yagli, Merve Basol Goksuluk, Ebru Aypar, Dursun Alehan, Melda SaglamHacettepe University. Munzur University. Sakarya University. Turkey Cardiology in the YoungCardiol Young 2026; DOI: 10.1017/S1047951125110895 AbstractPulmonary arterial hypertension leads to dyspnoea, fatigue, and oxygen desaturation, limiting activities of daily living and functional capacity. This study aimed to evaluate the impact of pulmonary

The relationship between muscle strength and oxygenation and activities of daily living in adolescents and young adults with pulmonary arterial hypertension Read More »

Pre-discharge car seat tolerance screening in infants with CHD: a single-centre review

Nicholas V. Barresi, Mary D. Schiff, Frederick Roberts, Sierra Brooks, Olivia Frosch, Evonne MorellChildren’s Hospital of Pittsburgh and University of Pittsburgh.United States Cardiology in the YoungCardiol Young 2026; DOI: 10.1017/S1047951125110731 AbstractObjective: To evaluate car seat tolerance screening failure rate in infants with CHD, clinical factors associated with test failure, and the impact of a failed test.Methods: Single-centre retrospective

Pre-discharge car seat tolerance screening in infants with CHD: a single-centre review Read More »

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