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Burden and outcomes of cardiovascular and pulmonary complications in adolescents and adults with sickle cell disease: a systematic review and meta-analysis

Natasha Kaweme, Sahar Buttress, Arthemon Nguweneza, Cynthia Phiri, Takudzwa Mtisi, Pauline Sambo, Gwendoline Kandawasvika, Hamakwa Mantina, Patience Kuona, Catherine Chunda-LiyokaUniversity Teaching Hospitals. University of Cape Town. University of Zimbabwe.Zambia, South Africa and Zimbabwe Systematic ReviewsSyst Rev 2026;DOI: 10.1186/s13643-026-03077-1 AbstractBackground: Sickle cell disease (SCD) is a genetic blood disorder associated with chronic cardiovascular and pulmonary complications, including pulmonary […]

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Association Between Hemodynamic Parameters and Gut Microbiota in Fontan Circulation: A Cross-Sectional Study

Saviga Sethasathien, Chanon Kunasol, Suchaya Silvilairat, Rekwan Sittiwangkul, Pannipa Suwannasom, Nipon Chattipakorn, Krit Leemasawat, Siriporn C. ChattipakornChiang Mai University. Thailand Journal of the American Heart AssociationJ Am Heart Assoc 2026; DOI: 10.1161/JAHA.125.045962 AbstractBackground: The Fontan operation results in chronic hemodynamic alterations, including central venous hypertension, which may contribute to gut dysbiosis. This study aimed to compare gut

Association Between Hemodynamic Parameters and Gut Microbiota in Fontan Circulation: A Cross-Sectional Study Read More »

Beyond the Echocardiogram: Cardiac Catheterization in Infants With Bronchopulmonary Dysplasia Associated Pulmonary Hypertension

Samuel J. Gentle, Audrey HebertYale School of Medicine. Centre Hospitalier Universitaire de Quebec.United States and Canada Journal of PediatricsJ Pediatr 2026; DOI: 10.1016/j.jpeds.2026.115026 AbstractAbstract Not Available CategoryClass III. Pulmonary Hypertension Associated with Lung DiseaseDiagnostic Testing for Pulmonary Vascular Disease. Non-invasive TestingDiagnostic Testing for Pulmonary Vascular Disease. Invasive Testing Age Focus: Pediatric Pulmonary Vascular Disease Fresh or

Beyond the Echocardiogram: Cardiac Catheterization in Infants With Bronchopulmonary Dysplasia Associated Pulmonary Hypertension Read More »

Impact of Hernia Sac in Congenital Diaphragmatic Hernia: Associations with Morbidity and Mortality

Krysta M Sutyak 1, Kylie I Holden 2, Charles Green 3, Matthew T Harting 2, KuoJen Tsao 4, Kouji Nagata 5, Richard Keijzer 6, Marietta Jank 6, Tim Jancelewicz 7, Joseph T Church 8, Pamela A Lally 2, Kevin P Lally 4; For, The Congenital Diaphragmatic Hernia Study Group McGovern Medical School and University of Texas Health Science Center at Houston and Children’s Memorial Hermann Hospital. Kyushu University. University of Manitoba. University of Tennessee Health Science Center. University of

Impact of Hernia Sac in Congenital Diaphragmatic Hernia: Associations with Morbidity and Mortality Read More »

Endomyocardial calcification with pulmonary and systemic hypertension in a term neonate with multisystem inflammatory syndrome of newborn (MIS-N)

Swasthi Kabi Satpathy. Choudri Muzafar Paswal, Neeraj Gupta, Jai Prakash Soni, Sushil Kumar ChoudharyAll India Institute of Medical Sciences Jodhpur. Dr Sampurnanand Medical College.India British Medical Journal Case ReportsBMJ Case Rep 2026; 19:DOI: 10.1136/bcr-2025-270053 AbstractMultisystem inflammatory syndrome in neonates (MIS-N) is a rare condition linked to perinatal exposure to SARS-CoV-2. We report a case of a

Endomyocardial calcification with pulmonary and systemic hypertension in a term neonate with multisystem inflammatory syndrome of newborn (MIS-N) Read More »

Estriol attenuates visceral adiposity and pulmonary artery smooth muscle cell proliferation via ERα-mediated signalling

Smriti Sharma, Joshua P. Dignam, Gregor Aitchison, Rosemary Gaw, Ioannis Stasinopolous, Ayman Gebril, Martin Wabitsch, Ruth Andrew, Margaret R. MacLeanUniversity of Strathclyde. Medical University of Vienna. Barts and The London School of Medicine and Dentistry and Queen Mary University of London. University of Edinburgh. Ulm University Medical Center. German Center for Child and Adolescent Health.United

Estriol attenuates visceral adiposity and pulmonary artery smooth muscle cell proliferation via ERα-mediated signalling Read More »

Cleavage and Polyadenylation Specificity Factor Subunit 5 Regulates Pulmonary Artery Smooth Muscle Expansion and Hypoxic Response

Scott D. Collum, Lisha Zhu, Tingting W. Mills, Rene Girard, Jamie Tran, Tinne C. J. Mertens, Cory Wilson, Nancy Wareing, Erik E. Suarez, Howard J. Huang, Rahat Hussain, Bindu Akkanti, Wenjin J. Zheng, Hari K. Yalamanchili, Bela Patel, Eric J. Wagner, Sandeep Agarwal, Harry Karmouty-QuintanaMcGovern Medical School University and McWilliams School of Biomedical Informatics of

Cleavage and Polyadenylation Specificity Factor Subunit 5 Regulates Pulmonary Artery Smooth Muscle Expansion and Hypoxic Response Read More »

Mixed effects of complement in a chronic murine model of inflammatory erosive arthritis and pulmonary vascular disease

Kiana L. Chen, Stacey Duemmel, Michael Christof, Gaochan Wang, H. Mark Kenney, Marc Nuzzo, Qingfu Xu, Benjamin Korman, Homaira RahimUniversity of Rochester Medical Center. United States Public Library of Science OnePLOS One 2026; 21: DOI: 10.1371/journal.pone.0340677 AbstractComplement’s role in the pathology of rheumatoid arthritis and pulmonary hypertension (PH) is not fully understood. We aimed to determine

Mixed effects of complement in a chronic murine model of inflammatory erosive arthritis and pulmonary vascular disease Read More »

Liver herniation in congenital diaphragmatic hernia is associated with delayed resolution of pulmonary hypertension

Uthaya Kumaran Kanagaraj, Mimi T.Y. Kuan, Michael Castaldo, Erik Skarsgard, Joseph Y. TingUniversity of British Columbia. University of Alberta.Canada Pediatrics and NeonatologyPediatr Neonatol 2026; DOI: 10.1016/j.pedneo.2025.11.011 AbstractBackground: Severe and persistent pulmonary hypertension (PH) predicts mortality and short-term pulmonary morbidity in infants with congenital diaphragmatic hernia (CDH). Intrathoracic liver herniation (liver-up) is a predictor of survival and increased

Liver herniation in congenital diaphragmatic hernia is associated with delayed resolution of pulmonary hypertension Read More »

Scimitar syndrome presenting in infancy

Charles B. Huddleston, Vernat Exil, Charles E. Canter, Eric N. MendeloffWashington University School of Medicine and St. Louis Children’s Hospital.United States Annals of Thoracic SurgeryAnn Thorac Surg 1999; 67: 154-159DOI: 10.1016/s0003-4975(98)01227-2 AbstractBackground: Scimitar syndrome has a variable presentation based on the age at which the diagnosis is made. In general, infants presenting in heart failure have a

Scimitar syndrome presenting in infancy Read More »

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