Medical Therapy. Efficacy or Lack of Efficacy

IDO-1 Promotes Pulmonary Vascular Remodeling Via Kynurenine Pathway in Pulmonary Arterial Hypertension

Zongye Cai, Ly Tu, Siyu Tian, Lin Deng, Yahong Fu, Carole Phan, Thierry P. P. van den Bosch, Karin Tran‐Lundmark, Bence M. Nagy, Horst Olschewski, Xiaoxuan Li, Sihao Wang, Danan Wang, Yi Yan, Lijun Fu, Karin A. Boomars, Christophe Guignabert, Daphne MerkusSecond Affiliated Hospital and Zhejiang University School of Medicine. Erasmus MC and University Medical Center. Pathophysiologie et Innovation Thérapeutique (HPPIT) and Université Paris-Saclay, School of Medicine. Eighth Affiliated Hospital of Sun Yat-sen University. Lund University and Skane University Hospital. Medical University […]

IDO-1 Promotes Pulmonary Vascular Remodeling Via Kynurenine Pathway in Pulmonary Arterial Hypertension Read More »

Targeted Therapy for Complex Lymphatic Anomalies in Patients with Noonan Syndrome and Related Disorders

Erika K. S. M. Leenders, Vera C. van den Brink, Lotte E. R. Kleimeier, Danielle T. J. Woutersen, Catelijne H. Coppens, Jeroen den Hertog, Willemijn M. Klein, Tuula Rinne, Sabine L. Vrancken, Saskia N. de Wildt, Jos M. T. Draaisma, Joris FuijkschotRadboud University Medical Center and Amalia Children’s Hospital. University Medical Center Utrecht. Leiden University.

Targeted Therapy for Complex Lymphatic Anomalies in Patients with Noonan Syndrome and Related Disorders Read More »

Pharmacological Treatment Practices for Patients with Congenital Heart Disease and Pulmonary Hypertension in Japan: Insights from the Japanese Association of Congenital Heart Disease Registry (JACPHR)

Taku Ishii, Keiko Uchida, Susumu Hosokawa, Reina Ishizaki, Naofumi F. Sumitomo, Yoshiyuki Furutani, Hidekazu Ishida, Shinichi Takatsuki, Kei Inai, Kunihiko Takahashi, Shigetoyo Kogaki, Hiroyuki Fukushima, Yuichi Tamura, Hiroyuki Yamagishi, Shozaburo Doi, Japanese Association of Congenital Heart Disease Registry (JACHDR) membersInstitute of Science Tokyo. Keio University School of Medicine, Tokyo Medical University. Japanese Red Cross Mushashino

Pharmacological Treatment Practices for Patients with Congenital Heart Disease and Pulmonary Hypertension in Japan: Insights from the Japanese Association of Congenital Heart Disease Registry (JACPHR) Read More »

Severe pertussis complicated by pulmonary hypertension in a Moroccan infant: a case report

Mehdi Belhakim, Zineb El jaouhahri, Aicha Boudar, Loubna Benaddi, Karima Naanani, Rachida Habbal, Abdelaziz ChlilekUniversity Hospital Ibn Rochd, Children’s Hospital and University Hassan II.Morocco Journal of Medical Case ReportsJ Med Case Rep 2025; 19: DOI: 10.1186/s13256-024-04898-1 AbstractBackground: Despite high vaccination coverage among children, pertussis continues to pose a significant public health challenge in Morocco. Mortality primarily affects

Severe pertussis complicated by pulmonary hypertension in a Moroccan infant: a case report Read More »

Pharmacologic Management of Segmental Pulmonary Hypertension in Children After Unifocalization and Pulmonary Artery Reconstruction: Initial Experience

Julian E. Cameron, Doff B. McElhinney, Esther Liu, Rachel K. Hopper, Ritu Asija, Manchula Navaratnam, Frank L. Hanley, Jeffrey A. FeinsteinLucile Salter Packard Children’s Hospital and Stanford University School of Medicine. Children’s Hospital Los Angeles and Keck School of Medicine University of Southern California.United States Pulmonary CirculationPulm Circ 2025; 15: DOI: 10.1002/pul2.70134 AbstractSegmental pulmonary hypertension (PH)

Pharmacologic Management of Segmental Pulmonary Hypertension in Children After Unifocalization and Pulmonary Artery Reconstruction: Initial Experience Read More »

Successful interventional closure of patent ductus arteriosus in three pediatric cases with congenital heart disease and severe pulmonary hypertension: a case series and literature review

Xiong-Yu Liao, Jun-Jie Li, Shao-Ying Zeng, Zhi-Wei Zhang, Yu-Mei XieChildren’s Medical Center, Sun Yat-sen Memorial Hospital and Sun Yat-sen University. Guangdong Provincial People’s Hospital (Guangdong Academy of Medical Sciences) and Southern Medical University.China Fontiers in Cardiovascular MedicineFront Cardiovasc Med 2025; DOI: 10.3389/fcvm.2025.1628666 AbstractPurpose: To report three cases of successful closure of patent ductus arteriosus (PDA) with severe

Successful interventional closure of patent ductus arteriosus in three pediatric cases with congenital heart disease and severe pulmonary hypertension: a case series and literature review Read More »

Response to two Janus kinase inhibitors in a boy with SAVI during 2-year follow-up: case report and literature review

Yiting Chen, Wenhe Zang, Haoyuan Zhong, Xianqin Deng, Wenting Zhong, Lianyu Wang, Xinying ChenSecond Affiliated Hospital of Guangzhou University of Chinese Medicine and Guangdong Provincial Hospital of Chinese Medicine.China Frontiers in ImmunologyFront Immunol 2025; 15: DOI: 10.3389/fimmu.2025.1615075 AbstractSTING-associated vasculopathy with onset in infancy (SAVI) represents an identified rare type I interferonopathy, triggered by gain-of-function mutations in

Response to two Janus kinase inhibitors in a boy with SAVI during 2-year follow-up: case report and literature review Read More »

Enhancing Drug Development for Paediatric Pulmonary Hypertension-An Integrative Perspective

Steven H. Abman, Sylvia M. Nikkho, Rolf M. F. Berger, Maria Jesus del Cerro, Eric D. Austin, Maurice Beghetti, Dunbar Ivy, Megan Griffiths, Anne Hilgendorff, Steven H. Kawut, Usha S. Krishnan, Mary P. Mullen, Shahin Moledina, Bernard Thébaud, Norman StockbridgeUniversity of Colorado School of Medicine and Children’s Hospital Colorado. Bayer AG. Beatrix Children’s Hospital, University

Enhancing Drug Development for Paediatric Pulmonary Hypertension-An Integrative Perspective Read More »

Variability in Home Oxygen Therapy Practices for Bronchopulmonary Dysplasia in Japan: A Questionnaire Survey

Ryo Ogawa, Masaki Hasebe, Tomohiko Nakamura, Fumihiko NambaNagano Children’s Hospital. Saitama Medical Center and Saitama Medical University.Japan Journal of Paediatrics and Child HealthJ Paediatr Child Health 2025; DOI: 10.1111/jpc.70150 AbstractAim: To examine variations in home oxygen therapy (HOT) initiation and management practices for bronchopulmonary dysplasia (BPD) among perinatal medical centres in Japan.Methods: A questionnaire survey was distributed to

Variability in Home Oxygen Therapy Practices for Bronchopulmonary Dysplasia in Japan: A Questionnaire Survey Read More »

Mortality Risk Factors and Survival Outcomes in Infants with Persistent Pulmonary Hypertension of the Newborn

Kokaew Chuaikaew, Gunlawadee Maneenil, Anucha Thatrimontrichai, Supaporn Dissaneevate, Manapat PraditaukritPrince of Songkla University.Thailand Journal of Clinical MedicineJ Clin Med 2025; 14: DOI: 10.3390/jcm14134502 AbstractBackground/Objectives: Persistent pulmonary hypertension of the newborn (PPHN) is characterized by increased pulmonary vascular resistance, resulting in severe hypoxemia. This study determined the factors associated with increased risk of mortality and survival rate

Mortality Risk Factors and Survival Outcomes in Infants with Persistent Pulmonary Hypertension of the Newborn Read More »

Scroll to Top