Medical Therapy. Efficacy or Lack of Efficacy Archives

Non-invasive nitric oxide use for pulmonary hypertension and pulmonary vascular disease associated with bronchopulmonary dysplasia in preterm infants

Aastha Chandra, Danielle R. Rios, Daniel Dagle, Patrick J. McNamara, Adrianne R. BischoffUniversity of Iowa.United States Journal of PerinatologyJ Perinatol 2026; DOI: 10.1038/s41372-026-02687-w AbstractAbstract Not Available CategoryClass III. Pulmonary Hypertension Associated with Lung DiseaseDiagnostic Testing for Pulmonary Vascular Disease. Non-invasive TestingMedical Therapy. Efficacy or Lack of Efficacy Age Focus: Pediatric Pulmonary Vascular Disease Fresh or Filed […]

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Outpatient Medication Prescribing Patterns in Bronchopulmonary Dysplasia: A Survey of Clinical Practices and Challenges

Michael C. Tracy, Joseph M. Collaco, Gangaram Akangire, Nicolas A. Bamat, Manvi Bansai, Sara K. Dawson, Lystra P. Hayden, Winston M. Manimtim, Antonia P. Popova, Demet Toprak, Sharon A. McGrath-Morrow, Paul E. MooreStanford University. Johns Hopkins University. Children’s Mercy Hospital. University of Missouri Kansas City School of Medicine. Children’s Hospital of Philadelphia and University of

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Early Results of Sotatercept Treatment in Patients With Severe Pulmonary Hypertension and a Potts Shunt

Manish A. Aggarwal, Kelly Merrill, Delphine Yung, R. Mark GradyWashington University and St Louis Children’s Hospital. University of Washington and Seattle Children’s Hospital.United States Pulmonary CirculationPulm Circ 2026; 16: DOI: 10.1002/pul2.70296 AbstractTwelve patients with severe pulmonary hypertension (PH) who had a pulmonary artery-to-descending aorta (Potts) shunt were treated with the novel PH drug sotatercept for an

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Case Report: Diffuse pulmonary lymphangiomatosis in a child

Ya-nan Zhang, Zhen Yuan, Jin-chen Du, Bin Liu, Fu Li, Shou-Cai Hu, Qing-Xin Li940th Hospital of Joint Logistics Support Force of Chinese People’s Liberation Army. Gansu University of Traditional Chinese Medicine.China Frontiers in PediatricsFront Pediatr 2026; 13: DOI: 10.3389/fped.2025.1591611 AbstractWe report a rare case of generalized lymphatic anomaly (GLA) in a 12-year-old male, presenting with intermittent

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Does inhaled nitric oxide treatment of pulmonary hypertension in extremely premature infants improve patient outcomes?

Tyler L. King, Patrick J. McNamara, Adrianne R. BischoffUniversity of Iowa.United States Journal of PerinatologyJ Perinatol 2026; DOI: 10.1038/s41372-026-02666-1 AbstractAbstract Not Available CategoryClass III. Pulmonary Hypertension Associated with Lung DiseaseMedical Therapy. Efficacy or Lack of Efficacy Age Focus: Pediatric Pulmonary Vascular Disease Fresh or Filed Publication: Fresh (PHresh). Less than 1-2 years since publication Article Access

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Melatonin effects on the left ventricular function in neonates with persistent pulmonary hypertension

Sarah M. Nofal, Abdel‑Rahman M. El‑Mashad, Asmaa M. Elmesiry, Amany M. Abouelenain, Mostafa M. AwnyTanta University.Egypt European Journal of PediatricsEur J Pediatr 2026; 185: DOI: 10.1007/s00431-026-06864-z AbstractThe aim of this study is to investigate the effects of melatonin on the left ventricular (LV) function in persistent pulmonary hypertension of the newborn (PPHN) and to assess its

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Lifesaving Compassionate-Use of Sotatercept in a 12-Year-old With Idiopathic Pulmonary Arterial Hypertension

Weronika Pelczar‐Płachta, Rafał Surmacz, Waldemar BobkowskiPoznan University of Medical Sciences.Poland Pulmonary CirculationPulm Circ 2026; 16DOI: 10.1002/pul2.70293 AbstractPediatric idiopathic pulmonary arterial hypertension (IPAH) refractory to maximal medical therapy is associated with high morbidity and mortality, and therapeutic options remain limited. We describe a 12-year-old girl with end-stage IPAH who developed acute decompensated right heart failure despite triple

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Sildenafil for bronchopulmonary dysplasia-associated pulmonary hypertension: A systematic search and narrative synthesis

Yoshinori Katayama, Katsuya Hirata, Yutaka Nishimura, Atsuko, Nakahari, Mami Takeoka, Masahiko Watanabe, Tetsuya Isayama, Japan Evidence Based NeonatologyTakatsuki General Hospital. Osaka Women’s and Children’s Hospital. Hiroshima City Hiroshima Citizens Hospital. Jichi Medical University Saitama Medical Center. Mie University Graduate School of Medicine. National Center for Child Health and Development.Japan Pediatrics InternationalPediatr Int 2026; 68: DOI: 10.1111/ped.70385

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Postnatal Steroids in Preterm Infants: A Narrative Review Series-Part 2: Cardiovascular Impacts

Phoenix Plessas-Azurduy, Anie Lapointe, Punnanee Wutthigate, Sarah Spénard, Andréanne Villeneuve, Audrey Hébert, Eilon Shany, Justin Richardson, Neta Geva, Wadi Mawad, Tiscar Cavallé-Garrido, Marc Beltempo, Wissam Shalish, Guilherme Sant’Anna, Gabriel AltMcGill University. Université de Montréal, CHU Sainte-Justine. Mahidol University. Montreal Children’s Hospital. CHU de Québec and Laval University. Saban Children’s Hospital and Soroka Medical Center. Ben

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Parenteral treprostinil in paediatric pulmonary arterial hypertension: a systematic review and meta-analysis

Julie Wacker, Raphael Joye, Maurice BeghettiGeneva University Hospitals and Faculty of Medicine and University of Geneva.Switzerland European Respiratory ReviewEur Respir Rev 2026; DOI: 10.1183/16000617.0033-2025 AbstractBackground: Paediatric pulmonary arterial hypertension (PAH) shares commonalities with adult disease but is essentially different regarding complexity and is usually more challenging to treat. Current treatment recommendations are based on expert opinion, small-scale

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