Medical Therapy. Efficacy or Lack of Efficacy

Case Report: Post-Total anomalous pulmonary venous connection pulmonary hypertension – novel treatment using sirolimus and atrial flow regulator implantation

Stasa Krasic, Antony Hermuzi, Ivan Dizdarevic, Vesna Topic, Nevena Djorovic, Mihail Basa, Vladislav VukomanovicMother and Child Health Institute of Serbia and University of Belgrade. Freeman Hospital and Newcastle upon Tyne Hospitals NHS Foundation Trust. Serbia and United Kingdom Frontiers in Cardiovascular MedicineFront Cardiovasc Med 2026; 13: DOI: 10.3389/fcvm.2026.1783773 AbstractObjective: In patients who have undergone surgical repair of […]

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A Life Without Lemons: A Case of Severe Pulmonary Arterial Hypertension Secondary to Vitamin C Deficiency in a Child With Autism Spectrum Disorder

Beau Redwood, Simon Erickson, Lily Loughman, Zoe VettenPerth Children’s Hospital. Genetic Services of Western Australia.Australia Journal of Pediatrics and Child HealthJ Pediatr Child Health 2026; DOI: 10.1111/jpc.70448 AbstractAbstract Not Available CategoryClass V. Pulmonary Hypertension Associated with Hematological, Systemic, Metabolic, Nutritional and Other DisordersMedical Therapy. Efficacy or Lack of Efficacy Age Focus: Pediatric Pulmonary Vascular Disease Fresh

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A Rare Case of Multi-System Involvement and Hereditary Pulmonary Hypertension Caused by De Novo Heterozygous CAV1 Mutation in a Pediatric Patient

Yan Sun, Qingyou Zhang, Yaqian Huang, Xueqin LiuPeking University First Hospital.China ChildrenChildren 2026; 13: DOI: 10.3390/children13050694 AbstractBackground: Pulmonary arterial hypertension is a rare but life-threatening condition in children, with hereditary forms often being linked to mutations in genes such as bone morphogenetic protein receptor type 2 (BMPR2), caveolin 1 (CAV1), and potassium channel subfamily K member

A Rare Case of Multi-System Involvement and Hereditary Pulmonary Hypertension Caused by De Novo Heterozygous CAV1 Mutation in a Pediatric Patient Read More »

Bilateral Congenital Chylothorax With Neonatal Ventilator-Associated Pneumonia and Sepsis: Diagnostic and Therapeutic Challenges: A Case Report

Leon B. Hajdari, Melihate Çekaj, Bese R. Morina, Vlere R. MorinaUniversity of Prishtina. University Clinical Center of Kosova.Kosovo American Journal of Case ReportsAm J Case Rep 2026; DOI: 10.12659/AJCR.952519 AbstractBackground: Congenital chylothorax is a rare condition characterized by the accumulation of lymph in the pleural space. It is the most common cause of neonatal pleural effusion,

Bilateral Congenital Chylothorax With Neonatal Ventilator-Associated Pneumonia and Sepsis: Diagnostic and Therapeutic Challenges: A Case Report Read More »

Scimitar syndrome presenting as respiratory distress in a term neonate: A rare case report

Iqra Javed, Musawer Khan, Haya, Sana Imtiaz, Muhammad Shoaib, MBBS, Yusra Iqbal, Khwaja Waleed Maqbool, Kamil Ahmad KamilCombined Military Hospital Quetta. SMBZAN Institute of Cardiology. Quetta Institute of Medical Sciences. Mirwais Regional Hospital.Pakistan and Afghanistan Radiology Case ReportsRadiol Case Rep 2026; 21: 2982-2987DOI: 10.1016/j.radcr.2026.03.021 AbstractScimitar syndrome is a rare congenital cardiopulmonary anomaly characterized by partial anomalous

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Pediatric autoimmune pancarditis complicated by congenital heart disease: a case of severe multivalvular dysfunction and fibrinous pericarditis

Pramod Kumar, Kumar Ratnjeet, Baiju Sasi Dharan, Rajalakshmi Poyuran, Arun GopalakrishnanSree Chitra Thirunal Institute for Medical Sciences and Technology. India Indian Journal of Thoracic and Cardiovascular SurgeryIndian J Thorac Cardiovasc Surg 2026; 42: 806-811DOI: 10.1007/s12055-026-02179-8 AbstractAutoimmune carditis in children is uncommon and often overlooked, particularly in regions where rheumatic fever is endemic. We report the case

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Early postoperative treprostinil in for severe pulmonary arterial hypertension in a high-risk pediatric patient with complete atrioventricular septal defect: a case report

Sha Zhao, Zhong-yuan Lu, Pantao Zhou, Li Xiong, Xiao-Bin LiAffiliated Traditional Chinese Medicine Hospital and Southwest Medical University. Beijing No.6 Hospital. Fuwai Hospital. Gulin Municipal Hospital of Traditional Chinese Medicine. China BioMedical Central Cardiovascular DisordersBMC Cardiovasc Disord 2026; DOI: 10.1186/s12872-026-05954-y AbstractBackground: Perioperative management of pediatric patients with congenital heart disease (CHD) and severe pulmonary arterial hypertension (PAH)

Early postoperative treprostinil in for severe pulmonary arterial hypertension in a high-risk pediatric patient with complete atrioventricular septal defect: a case report Read More »

Sotatercept administration in a young infant with severe pulmonary arterial hypertension: A case report

Arjith V. Rathakrishnan, Jenna Torgeson, Arij Beshish, Monica C. Bogenschutz, Vivek Balasubramaniam, Luke J. LamersUniversity of Wisconsin–Madison and UW Health Kids-Madison.United States Frontiers in PediatricsFront Pediatr 2026; DOI: 10.3389/fped.2026.1806079 AbstractIdiopathic pulmonary arterial hypertension (PAH) in infants is a rare, life-threatening condition characterized by elevated pulmonary artery pressure resulting from endothelial dysfunction, vasoconstriction, and vascular remodeling. The

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Amonafide Targeting NTSR1-PI3K/AKT/mTOR Signaling Attenuates Vascular Remodeling in Pulmonary Arterial Hypertension

Yong‐Jian Zhu, Jie‐Jian Kou, Ya‐Cong Bo, Meng‐Jie Zhang, Xin Fan, Lu‐Ling Zhao, Yi Yan, Hong Da Zhang, Wen‐Hui Wu, Ping Yuan, Yan Liu, Jun‐Zhuo Shi, Xiao‐Bin Pang, Yang‐Yang HeFirst Affiliated Hospital of Zhengzhou University. Huaihe Hospital and Henan University. Zhengzhou University. Shanghai Children’s Medical Center and Shanghai Jiao Tong University School of Medicine. Fuwai Hospital and Peking Union Medical College. Shanghai Pulmonary Hospital and School of Medicine Tongji University. China Journal of the American Heart AssociationJ Am Heart Assoc

Amonafide Targeting NTSR1-PI3K/AKT/mTOR Signaling Attenuates Vascular Remodeling in Pulmonary Arterial Hypertension Read More »

Descriptive study of the effects of treprostinil and/or epoprostenol in newborn infants with inhaled NO refractory persistent pulmonary hypertension of the newborn (PPHN)

Charlotte Mazepa, Sébastien Mur, Géraldine Gascoind, Laurent Storme, Nicolas Joram, Caroline Viard, Yves Dulac, Marine Butini, Sophie BreinigChildren’s Hospital, CHU de Toulouse and Université de Toulouse. Lille University Hospital. Jeanne-de-Flandre Hospital and CHU de Lille. Nantes University Hospital. Hôpital Femme-Mère-Enfant, Hospices civils de Lyon and Université Claude-Bernard-Lyon. France TherapeuticsTherapie 2026; DOI: 10.1016/j.therap.2026.03.001 AbstractBackground: Epoprostenol and treprostinil, prostacyclin

Descriptive study of the effects of treprostinil and/or epoprostenol in newborn infants with inhaled NO refractory persistent pulmonary hypertension of the newborn (PPHN) Read More »

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