Medical Therapy. Efficacy or Lack of Efficacy

Use of Dupilumab to Treat Cutaneous Complications of Continuous Prostacyclin Infusion in Pulmonary Hypertension: A Case Report and Review of Literature

Nidhy P. Varghese, Erin Ely, Rozmeen Fombin, Claire Champion, Elise WhalenBaylor College of Medicine and Texas Children’s Hospital.United States Pulmonary CirculationPulm Circ 2025; 15: DOI: 10.1002/pul2.70158 AbstractAdhesive reactions are common complications of continuous treprostinil infusions, limiting their recommended use as a treatment for severe pulmonary hypertension. We present the case of a 10-year-old male with recurrent […]

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Nebulized Treprostinil in Mechanically Ventilated Children

Sarah P. Cohen, Diane Paulus, Ashley Hattie, Beth Malehorn, Mary Irmen, Robert GajarskiOhio State University and Nationwide Children’s Hospital. United States Pediatric PulmonologyPediatr Pulmonol 2025; 60: DOI: 10.1002/ppul.71278 AbstractAbstract Not Available CategoryMedical Therapy. Efficacy or Lack of EfficacyMedical Therapy. Adverse Effects or Lack of Adverse EffectsMedical Therapy. Pharmacokinetics and Pharmacology Age Focus: Pediatric Pulmonary Vascular Disease

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Respiratory Outcomes Following Late Postnatal Dexamethasone Administration in Preterm Infants With Bronchopulmonary Dysplasia

Melissa House, James Rowe, Audrey Walters, Chunyan Liu, Shelley R. Ehrlich, Thomas Nienaber, Erik B. Hysinger, Paul Kingma, Shawn K. AhlfeldEmory University School of Medicine and Children’s Healthcare of Atlanta. Cincinnati Children’s Hospital Medical Center and University of Cincinnati College of Medicine.United States Pediatric PulmonologyPediatr Pulmonol 2025; 60: DOI: 10.1002/ppul.71275 AbstractObjective: To wean respiratory support, preterm infants

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Fetal therapies in congenital diaphragmatic hernia: a review of possibilities and practical challenges

Adriana Dekirmendjian, Fabian Doktor, Lina Antounians, Augusto ZaniUniversity of Toronto and Hospital for Sick Children. St. Louis Children’s Hospital and Washington University. Canada and United States Seminars in Fetal and Neonatal MedicineSemin Fetal Neonatal Med 2025; DOI: 10.1016/j.siny.2025.101656 AbstractCongenital diaphragmatic hernia (CDH) is characterized by pulmonary hypoplasia. CDH lungs exhibit an inflammatory signature with impaired growth,

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Less is More: ECMO Utilization and Outcomes in Congenital Diaphragmatic Hernia

Anastasia M. Kahan, Sommer Glasgow, Bradley A. Yoder, Michelle Yang, Christian C. Yost, Kelsea Peterson, Jack H. Scaife, Christopher E. Clinker, Erica Arnold, Stephen J. Fenton, Zachary J. Kastenberg, Robert A. Swendiman, Scott S. Short, Katie W. RussellUniversity of Utah.United States Journal of Pediatric SurgeryJ Pediatr Surg 2025; DOI: 10.1016/j.jpedsurg.2025.162571 AbstractPurpose: Infants with congenital diaphragmatic hernia (CDH)

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Utility of inhaled nitric oxide for pulmonary hypertension in cyanotic congenital heart disease: a cohort study with propensity score matching

Xiaofeng Wang, Chenyu Li, Shilin Wang, Zhiyuan Zhu, Qinnan Chen, Ruihuan Shen, Xu WangNational Center for Cardiovascular Disease and Fuwai Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College. Fuwai Yunnan Hospital, Chinese Academy of Medical Sciences amd Affiliated Cardiovascular Hospital of Kunming Medical University. Sir Run Run Shaw Hospital and Zhejiang University

Utility of inhaled nitric oxide for pulmonary hypertension in cyanotic congenital heart disease: a cohort study with propensity score matching Read More »

SUL-150 Limits Vascular Remodeling and Ventricular Failure in Pulmonary Arterial Hypertension

Lysanne M. Jorna, Dalibor Nakládal, Johannes N. van Heuveln, Diederik E. van der Feen, Quint A. J. Hagdorn, Guido P. L. Bossers, Annemieke van Oosten, Michel Weij, Ludmila Tkáciková, Sona Tkáciková, Robert H. Henning, Martin C. Harmsen, Rolf M. F. Berger, Guido KrenningUniversity Medical Center Groningen, University of Groningen. Comenius University Bratislava. University of Heidelberg.

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IDO-1 Promotes Pulmonary Vascular Remodeling Via Kynurenine Pathway in Pulmonary Arterial Hypertension

Zongye Cai, Ly Tu, Siyu Tian, Lin Deng, Yahong Fu, Carole Phan, Thierry P. P. van den Bosch, Karin Tran‐Lundmark, Bence M. Nagy, Horst Olschewski, Xiaoxuan Li, Sihao Wang, Danan Wang, Yi Yan, Lijun Fu, Karin A. Boomars, Christophe Guignabert, Daphne MerkusSecond Affiliated Hospital and Zhejiang University School of Medicine. Erasmus MC and University Medical Center. Pathophysiologie et Innovation Thérapeutique (HPPIT) and Université Paris-Saclay, School of Medicine. Eighth Affiliated Hospital of Sun Yat-sen University. Lund University and Skane University Hospital. Medical University

IDO-1 Promotes Pulmonary Vascular Remodeling Via Kynurenine Pathway in Pulmonary Arterial Hypertension Read More »

Targeted Therapy for Complex Lymphatic Anomalies in Patients with Noonan Syndrome and Related Disorders

Erika K. S. M. Leenders, Vera C. van den Brink, Lotte E. R. Kleimeier, Danielle T. J. Woutersen, Catelijne H. Coppens, Jeroen den Hertog, Willemijn M. Klein, Tuula Rinne, Sabine L. Vrancken, Saskia N. de Wildt, Jos M. T. Draaisma, Joris FuijkschotRadboud University Medical Center and Amalia Children’s Hospital. University Medical Center Utrecht. Leiden University.

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Pharmacological Treatment Practices for Patients with Congenital Heart Disease and Pulmonary Hypertension in Japan: Insights from the Japanese Association of Congenital Heart Disease Registry (JACPHR)

Taku Ishii, Keiko Uchida, Susumu Hosokawa, Reina Ishizaki, Naofumi F. Sumitomo, Yoshiyuki Furutani, Hidekazu Ishida, Shinichi Takatsuki, Kei Inai, Kunihiko Takahashi, Shigetoyo Kogaki, Hiroyuki Fukushima, Yuichi Tamura, Hiroyuki Yamagishi, Shozaburo Doi, Japanese Association of Congenital Heart Disease Registry (JACHDR) membersInstitute of Science Tokyo. Keio University School of Medicine, Tokyo Medical University. Japanese Red Cross Mushashino

Pharmacological Treatment Practices for Patients with Congenital Heart Disease and Pulmonary Hypertension in Japan: Insights from the Japanese Association of Congenital Heart Disease Registry (JACPHR) Read More »

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