Vascular Cell Biology and Mechanisms of Pulmonary Vascular Disease

High Shear Stress Reduces ERG Causing Endothelial-Mesenchymal Transition and Pulmonary Arterial Hypertension

Tsutomo Shinohara, Jan-Ranier Moonen, Yoon Hong Chun, Yannick C. Lee-Yow, Kenichi Okamura, Jason M. Szafron, Jordan Kaplan, Aiqin Cao, Lingli Wang, Divya Guntur, Shalina Taylor, Sarasa Isobe, Melody Dong, Weiguang Yang, Katherine Guo, Benjamin D. Franco, Cholawat Pacharinsak, Laura J. Pisani, Shinji Saitoh, Yoshihide Mitani, Alison L. Marsden, Jesse M. Engreitz, Jakob Körbelin, Marlene RabinovitchLucile […]

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Alterations in Mitochondrial Function in Pulmonary Vascular Diseases

Samar Farha, Kewal Asosingh, Paul M. Hassoun, John Barnard, Suzy Comhair, Andrew Reichard, Nicholas Wanner, Milena Radeva, Micheala A. Aldred, Gerald J. Beck, Erika Berman-Rosenzweig, Barry A. Borlaug, J. Emanuel Finet, Robert P. Frantz, Gabriele Grunig, Anna R. Hemnes, Nicholas Hill, Evelyn M. Horn, Chistine Jellis, Jane A. Leopold, Reena Mehra, Margaret M. Park, Franz

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Cytochrome P450-derived Epoxyeicosatrienoic Acid, the Regulation of Cardiovascular-related Diseases, and the Implication for Pulmonary Hypertension

Run Lan, Meng-Jie Zhang, Ke Liu, Fang-Fang Meng, Xiao-He Xu, Chen-Chen Wang, Meng-Qi Zhang, Yi Yan, Jie-Jian Kou, Lu-Ling Zhao, Yang-Yang He, Hong-Da ZhangHuaihe Hospital and Henan University. Shanghai Children’s Medical Center, National Children’s Medical Center and Shanghai Jiao Tong University School of Medicine. Fuwai Hospital, National Center for Cardiovascular Diseases and Chinese Academy of

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THBS1 mediates hypoxia driven EndMT in pulmonary hypertension

Bingming Peng, Yingzhen Zhou, Xingmeng Fu, Li Chen, Zhengxia Pan, Qijian Yi, Tengteng Zhao, Zhou Fu, Ting WangChildren’s Hospital of Chongqing Medical University, National Clinical Research Center for Child Health and Disorders and Ministry of Education Key Laboratory of Child Development and Disorders. University of California, San Diego.China and United States Pulmonary CirculationPulm Circ 2024;

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T follicular helper cell is essential for M2 macrophage polarization and pulmonary vascular remodeling in hypoxia-induced pulmonary hypertension

Cheng Li, Pingping Liu, Hao Zhu, Huan Yang, Jun Zha, Huiling Yao, Shaoze Zhang, Jin Huang, Guang Li, Gang Jiang, Yongliang Jiang, Aiguo DaiHunan Provincial People’s Hospital and First Affiliated Hospital of Hunan Normal University. Hunan Children’s Hospital. Changsha Central Hospital and University of South China. Hunan University of Chinese Medicine. China Respiratory ResearchRespir Res

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The Glu86 Residue in TBX4 Proves Critical for Human Lung Development

Przemyslaw Szafranski, Tomasz Gambin, Gail Deutsch, Salma A. Nassef, Mary Clay Dailey, Debra L. Kearney, Pawel StankiewiczBaylor College of Medicine and Texas Children’s Hospital. Warsaw University of Technology. University of Washington School of Medicine. United States and Poland American Journal of Medical Genetics Part AAm J Med Genet A 2024; DOI: 10.1002/ajmg.a.63936 AbstractT-box transcription factors are

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Increased BMP-Responsive Transcription Factors in Distinct Endothelial and Mesenchymal Cells in PAH

Abam Michael Andruska, Rodrigo Cantu Valadez, Kenzo Ichimura, Pauline Chu, Tianyi Zhang, Katharina Schimmel, Lingli Wang, Aiqin Cao, Michaela A. Aldred, Edda SpiekerkoetterStanford University. University of California Berkeley. Indiana University School of Medicine.United States American Journal of Respiratory and Critical MedicineAm J Respir Crit Care Med 2024; DOI: 10.1164/rccm.202405-1039LE AbstractAbstract Not Available CategoryVascular Cell Biology and

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The molecular consequences of FOXF1 missense mutations associated with alveolar capillary dysplasia with misalignment of pulmonary veins

G. G. Edel, M. van Kempen, A. Boerema‑de Munck, C. N. Huisman, C. A. P. Naalden, R. W. W. Brouwer, S. Koornneef, W. F. J. van IJcken, R. M. H. Wijnen, R. J. RottierErasmus MC-Sophia. Netherlands Journal of Biomedical ScienceJ Biomed Sci 2024; 31: DOI: 10.1186/s12929-024-01088-5 AbstractBackground: Alveolar capillary dysplasia with misalignment of pulmonary veins (ACD/MPV) is

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A bovine model of hypoxia-induced pulmonary hypertension reveals a gradient of immune and matrisome response with a complement signature found in circulation

Jason Williams, Franklyn N. Iheagwam, Sean P. Maroney, Lauren R. Schmitt, R. Dale Brown, Greta M. Krafsur, Maria G. Frid, Maxwell C. McCabe, Aneta Gandjeva, Kurt J. Williams, James P. Luyendyk, . Anthony J. Saviola, Rubin M. Tuder, Kurt Stenmark, Kirk C. HansenUniversity of Colorado Denver and University of Colorado Anschutz Medical Campus. Michigan State

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Panorama of artery endothelial cell dysfunction in pulmonary arterial hypertension

Ying-Huizi Shen, Dong Ding, Tian-Yu Lian, Bao-Chen Qui, Yi Yan, Pei-Wen Wang, Wei-Hua Zhang, Zhi-Cheng JingFirst Hospital of Jilin University. Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College. Guangdong Provincial People’s Hospital and Guangdong Academy of Medical Sciences, Southern Medical University. Shanghai Children’s Medical Center, National Children’s Medical Center

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