Heart Dysfunction Associated with Pulmonary Vascular Disease

Melatonin effects on the left ventricular function in neonates with persistent pulmonary hypertension

Sarah M. Nofal, Abdel‑Rahman M. El‑Mashad, Asmaa M. Elmesiry, Amany M. Abouelenain, Mostafa M. AwnyTanta University.Egypt European Journal of PediatricsEur J Pediatr 2026; 185: DOI: 10.1007/s00431-026-06864-z AbstractThe aim of this study is to investigate the effects of melatonin on the left ventricular (LV) function in persistent pulmonary hypertension of the newborn (PPHN) and to assess its

Melatonin effects on the left ventricular function in neonates with persistent pulmonary hypertension Read More »

Lifesaving Compassionate-Use of Sotatercept in a 12-Year-old With Idiopathic Pulmonary Arterial Hypertension

Weronika Pelczar‐Płachta, Rafał Surmacz, Waldemar BobkowskiPoznan University of Medical Sciences.Poland Pulmonary CirculationPulm Circ 2026; 16DOI: 10.1002/pul2.70293 AbstractPediatric idiopathic pulmonary arterial hypertension (IPAH) refractory to maximal medical therapy is associated with high morbidity and mortality, and therapeutic options remain limited. We describe a 12-year-old girl with end-stage IPAH who developed acute decompensated right heart failure despite triple

Lifesaving Compassionate-Use of Sotatercept in a 12-Year-old With Idiopathic Pulmonary Arterial Hypertension Read More »

Clinical Utility of Stroke Volume Index in Children with Idiopathic and Heritable Pulmonary Arterial Hypertension

Shinichi Takatsuki, Kinjal Parikh, Mio Sato, Yuta Kawamura, Yurika Shimizu, Reiko Kawai, Dunbar IvyToho University Omori Medical Center. Inova Children’s Hospital. University of Colorado School of Medicine.Japan and United States Pediatric CardiologyPediatr Cardiol 2026; DOI: 10.1007/s00246-026-04241-z AbstractTo determine the prognostic value of stroke volume index (SVi) in children with idiopathic and heritable pulmonary arterial hypertension (PAH).

Clinical Utility of Stroke Volume Index in Children with Idiopathic and Heritable Pulmonary Arterial Hypertension Read More »

Relationships between lung ultrasound, chest CT, and echocardiographic findings in children with bronchopulmonary dysplasia: A multimodal imaging study

Andrea Maria Comisi, Giuseppe Fabio Parisi, Francesco Fabrizio Comisi, Salvatore Carnazzo, Pietro Sciacca, Alessandra Li Pomi, Sara Manti, Salvatore LeonardiSan Marco Hospital and University of Catania. Microcitemico Hospital “A. Cao” and University of Cagliari. University of Enna “Kore”. University of Messina. Italy Respiratory MedicineRespir Med 2026; DOI: 10.1016/j.rmed.2026.108775 AbstractThis study investigates the use of integrated imaging

Relationships between lung ultrasound, chest CT, and echocardiographic findings in children with bronchopulmonary dysplasia: A multimodal imaging study Read More »

Alternative Polyadenylation Signatures Distinguish Maladaptive Right Ventricular Remodeling in Pulmonary Hypertension: Implications for RNA-Based Diagnostics and Therapeutics

Janani Subramaniam, Venkata Jonnakuti, Scott D. Collum, Sandra Martineau, Kai-Lieh Huang, Sandra Breuils-Bonnet, Andrea L. Frump, Bindu H. Akkanti, Jayeshkumar A. Patel, Manish K. Patel, Ismael Salas de Armas, Isabella N. Lefebvre, Rajko Radovancevic, Elvin Blanco, Eric J. Wagner, Igor Gregoric, Sriram Nathan, Biswajit Kar, Steeve Provencher, Sebastien Bonnet, François Potus, Hari Krishna Yalamanchili, Harry

Alternative Polyadenylation Signatures Distinguish Maladaptive Right Ventricular Remodeling in Pulmonary Hypertension: Implications for RNA-Based Diagnostics and Therapeutics Read More »

Myocardial work during various right ventricle load conditions in a paediatric population

Ramona Ghenghea, Pierrick Pyra, Yves Dulac, Aitor Guitarte, Paul Vignaud, Philippe Acar, Khaled Hadeed, Clement KarsentyChildren’s Hospital, CHU Toulouse and Paul Sabatier University. France Achives of Cardiovascular DiseaseArch Cardiovasc Dis 2026; DOI: 10.1016/j.acvd.2025.11.013 AbstractBackground: Assessing right ventricular (RV) function in children is challenging, particularly in RV overload, where conventional echocardiographic indices do not account for afterload.Aims: This prospective

Myocardial work during various right ventricle load conditions in a paediatric population Read More »

Pathophysiology and prevalence of high output heart failure in group 1 pulmonary hypertension

Yogesh N V Reddy 1, Robert P Frantz 2, William R Miranda 2, Revati Varma 2, Paul M Hassoun 3, Anna R Hemnes 4, Evelyn Horn 5, Jane A Leopold 6, Franz Rischard 7, Erika B Rosenzweig 8, Nicholas S Hill 9, Serpil C Erzurum 10, Gerald J Beck 11, Samar Farha 12, J Emanuel Finet 12, Christine Jellis 12, Deborah Kwon 12, Stephen Mathai 3, Margaret Park 12, W H Wilson Tang 12, Barry A Borlaug 2; PVDOMICS Study GroupMayo Clinic. Johns Hopkins University. Vanderbilt University Medical Center. Weill Cornell Medicine. Brigham and Women’s Hospital and

Pathophysiology and prevalence of high output heart failure in group 1 pulmonary hypertension Read More »

Current State of RV Multimodality Imaging in Pediatric Pulmonary Hypertension: Current Evidence, Knowledge Gaps, and Future Research Directions

Kimberley G. Miles, Dan M. Dorobantu, Johannes Menno Douwes, Benjamin S. Frank, Pei-Ni Jone, Vivek Muthurangu, D. Dunbar Ivy, Hythem Nawaytou, Mark K. FriedbergCincinnati Children’s Hospital and University of Cincinnati College of Medicine. Bristol Royal Hospital for Children and Heart Institute. Beatrix Children’s Hospital, University Medical Center Groningen and University of Groningen. University of Colorado Denver Anschutz

Current State of RV Multimodality Imaging in Pediatric Pulmonary Hypertension: Current Evidence, Knowledge Gaps, and Future Research Directions Read More »

Right ventricular adaptation in congenital heart disease: Does the type of right ventricular overload matter?

Renee S. Joosen, Gregor J. Krings, Heleen B. van der Zwaan, Nefise Karaman, Marco Guglielmo, Lucas R. Celant, Marco J. W. G€otte, Michael G. Dickinson, Michiel Voskuil, Marielle C. van de Veerdonk, Johannes M. P. J. BreurUniversity Medical Center Utrecht. Amsterdam University Medical Center and University of Amsterdam. Netherlands Journal of Thoracic and Cardiovascular Surgery

Right ventricular adaptation in congenital heart disease: Does the type of right ventricular overload matter? Read More »

AI learning for pediatric right ventricular assessment: development and validation across multiple centers

Charitha Reddy, Yi Yan, Min Qiu, Yi Tang, Bo Jin, Zhi Han, Yuhang Li, Sihan Zhou, Qiming Tang, Huan Xiao, Shu Yang, Qigui Wen, Lan-Ping Wu, Li-Jun Fu, Ze-Yu Jing, Yi-Jia Yang, Yu-Qi Zhang, Naoto Ozawa, Takumi Ichikawa, Ellen Ling, Ronald J. Wong, Nima Aghaeepour, Brice Gaudilliere, Martin S. Angst, Karl G. Sylvester, Harvey J.

AI learning for pediatric right ventricular assessment: development and validation across multiple centers Read More »

Scroll to Top