Heart Dysfunction Associated with Pulmonary Vascular Disease

SnRNA-seq identifies FN1-SDC4 axis triggering epicardial activation in right ventricular remodeling in pulmonary hypertension

Xiao-He Xu, Yi Shen, Min Chen, Yu-Xin Miao, Lin Cheng, Yang-Han-Yue Zhao, Yang Fang, Dai-Ji Jiang, Fang Yu, Yang-Yang He, Zhuo-Yuan Xu, Li-Jun Fu, Li-Wei Wu, Hao Zhang, Yi YanShanghai Children’s Medical Center, National Children’s Medical Center and Shanghai Jiao Tong University School of Medicine. Henan University. Second Affiliated Hospital, Yuying Children’s Hospital, Wenzhou Medical

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Association between hepatic vein Doppler and echocardiographic diastolic indices with invasively measured right ventricular filling pressures in pediatric pulmonary arterial hypertension

Tessa Palmeri, Wei Hui, Charles T. Simpkin, Andreea Dragulescu, Luc Mertens, Dunbar Ivy, Dale Burkett, Mark FriedbergHospital for Sick Children. University of Colorado Medical Campus.Canada and United States International Journal of CardiologyInt J Cardiol 2026; DOI: 10.1016/j.ijcard.2026.134619 AbstractBackground: Increased right ventricular filling pressures (RVFP) are associated with increased mortality risk in children with pulmonary arterial hypertension (PAH).

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Caring for the smallest hearts: cardiovascular phenotypes and assessment in tiny babies

Srirupa Hari Gopal, Shweta Parmekar, Eugene Dempsey, Mohan PammiSSM Health Cardinal Glennon Children’s Hospital and Saint Louis University. Baylor College of Medicine and Texas Children’s Hospital.  University College Cork.United States and Ireland Pediatric ResearchPediatr Res 2026; DOI: 10.1038/s41390-026-05164-4 AbstractWith improving survival, periviable neonates (≤25 weeks’ gestation) represent a dynamic, but under-studied population in neonatal care, with

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Pediatric heart failure: A focus on low-income countries

Sulafa Km AliUniversity of Sharjah.United Arab Emirates World Journal of Clinical PediatricsWorld J Clin Pediatr 2026; 15: DOI: 10.5409/wjcp.v15.i2.115168 AbstractHeart failure (HF) in the pediatric population is unique because it involves heterogeneous groups of diseases, including congenital and acquired conditions. The etiology of HF varies with age and sociodemographic origin. In low-income countries, unoperated congenital heart

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Case Report: Post-Total anomalous pulmonary venous connection pulmonary hypertension – novel treatment using sirolimus and atrial flow regulator implantation

Stasa Krasic, Antony Hermuzi, Ivan Dizdarevic, Vesna Topic, Nevena Djorovic, Mihail Basa, Vladislav VukomanovicMother and Child Health Institute of Serbia and University of Belgrade. Freeman Hospital and Newcastle upon Tyne Hospitals NHS Foundation Trust. Serbia and United Kingdom Frontiers in Cardiovascular MedicineFront Cardiovasc Med 2026; 13: DOI: 10.3389/fcvm.2026.1783773 AbstractObjective: In patients who have undergone surgical repair of

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Clinical Utility and Limitations of TAPSE in Pediatric Echocardiography: A Narrative Review

Matei Mselle, Ronald MbwasiHaydom Lutheran Hospital. Kilimanjaro Christian Medical Centre and Kilimanjaro Christian Medical University.Tanzania EchocardiographyEchocardiography 2026; 43: DOI: 10.1111/echo.70516 AbstractBackground: Tricuspid annular plane systolic excursion (TAPSE) is widely used to assess right ventricular (RV) longitudinal systolic function in pediatric echocardiography; however, its reliability is influenced by developmental physiology.Objective: To evaluate the clinical utility, age-dependent variability, and limitations

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Echocardiographic Detection of Pulmonary Hypertension and Right Ventricular Failure in Infants with Bronchopulmonary Dysplasia: A Survey of the BPD Collaborative

Shilpa Vyas-Read, Shazia Bhombal, Roopa Siddaiah, Clifford L. Cua, Amulya Buddhavarapu, Robin L. McKinney, Philip T. Levy, Amanda L. Hauck, Nicolas F. M. Porta, Kathleen A. Gibbs, Krithika Lingappan, Matthew S. Douglass, Eric D. Austin, Steven H. Abman, Ronald W. DayEmory University and Children’s Healthcare of Atlanta. Arkansas Children’s Hospital. Ohio State University and Nationwide

Echocardiographic Detection of Pulmonary Hypertension and Right Ventricular Failure in Infants with Bronchopulmonary Dysplasia: A Survey of the BPD Collaborative Read More »

The Right Ventricle, the Forgotten Chamber or Not

Ranjini Srinivasan, Alessandro Castiglione, Michael Antonchak, Ellen OstenfeldWeill Cornell School of Medicine. Lund University and Skåne University Hospital. New York University Grossman School of Medicine.United States and Sweden Magnetic Resonance Imaging Clinics of North AmericaMagn Reson Imaging Clin N Am 2026; 34: 217-230DOI: 10.1016/j.mric.2026.01.011 AbstractRight ventricular (RV) enlargement or dysfunction evaluation is the cornerstone for diagnosis, prognostications, and treatment planning in a variety

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Metabolomics of Right Ventricular Function in Pulmonary Hypertension

Jonathan Chacon-Barahona, Samuel J Chung, Jonah D Garry, Robert Frantz, Franz Rischard, Paul M Hassoun, Stephen C Mathai, Catherine E Simpson, Gerald Beck, Nicholas S Hill, Jane A Leopold, Aaron B Waxman, Erika B Rosenzweig, Barry A Borlaug, Monica Mukherjee, Rebecca Vanderpool, Miriam Jacob, Reena Mehra, Margaret M Park, J Emanuel Finet, Samar Farha, Gabriele Grunig, Deborah Kwon, Suzy Comhair, Serpil Erzurum, John Barnard, Bo Hu, Christine L Jellis, Alexandra Christin Racanelli, Jan Krumsiek, Evan L Brittain, Anna Hemnes, Evelyn Horn; PVDOMICS Study GroupWeill Cornell Medical College. Albert

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Identification of RUNX1 as a Biomarker for Right Ventricular Remodeling in Pulmonary Arterial Hypertension Using WGCNA

Wenjie Chen, Min Peng, Yusi Chen, Jun Luo, Jingyuan Chen, Haihua Qiu, Jiang LiSecond Xiangya Hospital of Central South University. Third Xiangya Hospital Central South University.China Pulmonary CirculationPulm Circ 2026; 16: DOI: 10.1002/pul2.70297 AbstractRight ventricle (RV) dysfunction is central to pulmonary arterial hypertension (PAH) yet its molecular mechanisms remain unclear. This study aimed to identify biomarkers

Identification of RUNX1 as a Biomarker for Right Ventricular Remodeling in Pulmonary Arterial Hypertension Using WGCNA Read More »

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